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Embryonic immune sensor could key to creating patient-derived blood stem cells

A microbial sensor that helps identify and fight bacterial infections also plays a key role in the development of blood stem cells, valuable new insight in the effort to create patient-derived blood stem cells that could eliminate the need for bone marrow transplants.

19 Dec 2023

Kyoto scientists map double whammy gene clusters for anxiety disorders

Anxiety disorders (ADs) affect more than 280 million people worldwide, making them one of the most common mental health conditions. ADs have a genetic basis as seen from inheritance in families, and people with one subtype of AD tend to have another subtype, suggesting a shared genetic basis.

19 Dec 2023

Scientists design non-hallucinogenic psychedelic treatments potentially accelerating research on mental health benefits

Researchers identified 5-hydroxytryptamine 2A (5-HT2A) receptor (5-HT2AR) signaling pathways associated with psychedelic potential.

19 Dec 2023

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Researchers investigated the anticancer effects of drugs targeting human tumor-associated macrophages (TAMs) in vivo. In humanized murine models, they tested the effectiveness of an antibody to human signal regulatory protein alpha (SIRPα) for cancer immunotherapy.

19 Dec 2023

Common heart medication causes false positives on Alzheimer's blood test

Researchers from the University of Gothenburg, in collaboration with colleagues from University of Glasgow, present data that the drug Entresto (sacubitril/valsartan) which is commonly used for the treatment of cardiac failure leads to a marked reduction in plasma Aβ ratio, a candidate blood test for Alzheimer's disease (AD).

18 Dec 2023

Cinnamon extract shows promise in reducing obesity by inhibiting fat cell growth and boosting fat breakdown

Study reveals that cinnamon extract significantly inhibits adipocyte differentiation and lipid accumulation, offering potential benefits against obesity by reducing fat production and enhancing lipolysis in both cell models and mice.

18 Dec 2023

Shattering myths: Study reveals new insights on type 1 diabetes and obesity link

Review examines the relationship between type 1 diabetes and weight disorders, debunking myths about T1D and offering recommendations for future research and therapeutic interventions.

18 Dec 2023

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine.

18 Dec 2023

Study reveals similarity between the memory processing of AI models and the brain's hippocampus

An interdisciplinary team consisting of researchers from the Center for Cognition and Sociality and the Data Science Group within the Institute for Basic Science (IBS) revealed a striking similarity between the memory processing of artificial intelligence (AI) models and the hippocampus of the human brain.

18 Dec 2023

Psilocybin may benefit individuals with cancer and major depression

Results from a phase II clinical trial indicate that psilocybin, a hallucinogenic chemical found in certain mushrooms of the genus Psiloybe, may benefit individuals with cancer and major depression.

18 Dec 2023

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

In a clinical trial of patients with chronic kidney disease, an experimental drug significantly reduced albuminuria - albumin in urine, a sign of kidney damage - for 50% of participants.

15 Dec 2023

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells.

15 Dec 2023

QUT scientists discover promising treatment for fatal endometrial cancer

QUT scientists have discovered a promising new therapy for a deadly type of endometrial cancer that has a poor prognosis if the cancer spreads or returns after initial treatment, a plight that affects 15-20 per cent of endometrial cancer patients.

15 Dec 2023

Research shows how the immune system keeps Herpes simplex virus at bay

Herpes simplex virus (HSV) is extremely common, affecting nearly two-thirds of the world's population, according to the World Health Organization.

14 Dec 2023

NIAID study identifies critical T-cell function missing in prior HIV vaccine candidates

An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleagues.

14 Dec 2023

How safe are GLP-1R agonists in early pregnancy?

JAMA Internal Medicine study examines the safety of GLP-1 receptor agonists and other second-line antidiabetic medications during early pregnancy, finding no significant increase in congenital anomalies compared to insulin use.

14 Dec 2023

Internationally renowned breast medical oncologist joins the David Geffen School of Medicine at UCLA

Dr. Aditya Bardia, a renowned breast medical oncologist and physician scientist who specializes in developing novel targeted and personalized therapies, has joined the David Geffen School of Medicine at UCLA and the UCLA Health Jonsson Comprehensive Cancer Center where he will assume several leadership roles across the institution.

14 Dec 2023

Receptor News and Research

Embryonic immune sensor could key to creating patient-derived blood stem cells

Kyoto scientists map double whammy gene clusters for anxiety disorders

Scientists design non-hallucinogenic psychedelic treatments potentially accelerating research on mental health benefits

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Common heart medication causes false positives on Alzheimer's blood test

Cinnamon extract shows promise in reducing obesity by inhibiting fat cell growth and boosting fat breakdown

Shattering myths: Study reveals new insights on type 1 diabetes and obesity link

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Study reveals similarity between the memory processing of AI models and the brain's hippocampus

Psilocybin may benefit individuals with cancer and major depression

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

QUT scientists discover promising treatment for fatal endometrial cancer

Research shows how the immune system keeps Herpes simplex virus at bay

NIAID study identifies critical T-cell function missing in prior HIV vaccine candidates

How safe are GLP-1R agonists in early pregnancy?

Internationally renowned breast medical oncologist joins the David Geffen School of Medicine at UCLA

Atezolizumab plus carboplatin: A winning combination for metastatic triple-negative breast cancer

Novel machine learning tool predicts gain- and loss-of-function variants across the genome

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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