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Merck presents data on investigational cladribine tablets in relapsing multiple sclerosis

Merck announced the presentation of new analyses of efficacy and safety data for investigational Cladribine Tablets in poster presentations at the Annual Meeting of the American Academy of Neurology (AAN), that took place April 22 – 28, 2017, in Boston, Massachusetts.

3 May 2017

NIST chemists publish new data on important compound’s thermodynamic properties

Amantadine hydrochloride may be the most common medication you've never heard of. This compound has been around for decades as the basis for antiviral and other medications, from flu therapy to treatments for brain disorders such as Parkinson's disease and the fatigue associated with multiple sclerosis.

2 May 2017

Infantile spasms and multiple sclerosis relapse data presented at AAN

Mallinckrodt plc, a specialty pharmaceutical company, announced new results from two company-sponsored studies: one study on use of H.P. Acthar® Gel (repository corticotropin injection) in patients with infantile spasms (IS) and a second study on the economic burden of moderate-to-severe multiple sclerosis (MS) relapse.

2 May 2017

Study highlights risk factors for widespread vitamin D deficiency

Results from a clinical review published in The Journal of the American Osteopathic Association find nearly 1 billion people worldwide may have deficient or insufficient levels of vitamin D due to chronic disease and inadequate sun exposure related to sunscreen use.

2 May 2017

Nose2Brain project aims to develop better therapy for multiple sclerosis

Medically active substances are normally distributed via the blood - either directly by injection into the bloodstream or indirectly, for example through the digestive tract after oral administration.

27 Apr 2017

Antidepressant improves drug delivery across the blood-brain barrier, rat study shows

NIH rat study suggests amitriptyline temporarily inhibits the blood-brain barrier, allowing drugs to enter the brain.

27 Apr 2017

Simple eye test can diagnose early signs of glaucoma

A SIMPLE eye test could help solve the biggest global cause of irreversible blindness, glaucoma. In clinical trials, the pioneering diagnostic -- developed by researchers at University College London and the Western Eye Hospital -- allowed doctors to see individual nerve cell death in the back of the eye.

27 Apr 2017

Improvements to animal testing protocols could yield more useful clinical results

The use of animals in biomedical research has long been the focus of campaigns by animal rights activists. Two leading scientists writing in the European Journal of Internal Medicine give their expert view of the importance of animal testing to medical progress and present ways it could be further improved to yield more useful clinical results.

27 Apr 2017

Study provides preliminary evidence that Parkinson's disease may start in the gut

Parkinson's disease may start in the gut and spread to the brain via the vagus nerve, according to a study published in the April 26, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology. The vagus nerve extends from the brainstem to the abdomen and controls unconscious body processes like heart rate and food digestion.

27 Apr 2017

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

Regenerative medicine using human pluripotent stem cells to grow transplantable tissue outside the body carries the promise to treat a range of intractable disorders, such as diabetes and Parkinson's disease.

26 Apr 2017

Brain’s ability to rewire after injury can lead to long-term strains

Like air-traffic controllers scrambling to reconnect flights when a major hub goes down, the brain has a remarkable ability to rewire itself after suffering an injury.

25 Apr 2017

New guidelines provide practical information on sudden unexpected death in epilepsy

There is an uncommon risk of death that people with epilepsy and their loved ones may not know about. The risk is called sudden unexpected death in epilepsy, or SUDEP. Now the American Academy of Neurology and the American Epilepsy Society have co-developed a new guideline on SUDEP, published in the April 24, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology, and presented at the 69th AAN Annual Meeting in Boston, April 22 to 28, 2017.

25 Apr 2017

Researchers discover new cellular mechanism that may cause multiple sclerosis

A new study has made a major new discovery towards finding the cause of multiple sclerosis (MS), potentially paving the way for research to investigate new treatments.

24 Apr 2017

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Biogen today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion recommending the granting of a marketing authorization for SPINRAZA to treat patients with spinal muscular atrophy (SMA).

21 Apr 2017

Latest advances in antibody delivery mediated by rAAV for treatment of chronic and infectious diseases

Monoclonal antibody-based therapies have revolutionized treatments of cancer and autoimmune diseases because of their specificity and limited toxicity.

21 Apr 2017

People with multiple sclerosis begin to show symptoms much earlier than previously thought

People with multiple sclerosis can show signs of something wrong five years before the onset of disease, much earlier than previously thought, according to a new analysis of health records from people with the condition.

21 Apr 2017

Research shows potential way to limit damage to the brain caused by seizure disorder

Tiny vesicles isolated from adult mesenchymal stem cells and administered intranasally can limit the damage to the brain of animal models caused by a seizure disorder called status epilepticus, according to research published this week in the Proceedings of the National Academy of Sciences.

21 Apr 2017

Sclerosis News and Research

Merck presents data on investigational cladribine tablets in relapsing multiple sclerosis

NIST chemists publish new data on important compound’s thermodynamic properties

Infantile spasms and multiple sclerosis relapse data presented at AAN

Study highlights risk factors for widespread vitamin D deficiency

Nose2Brain project aims to develop better therapy for multiple sclerosis

Antidepressant improves drug delivery across the blood-brain barrier, rat study shows

Simple eye test can diagnose early signs of glaucoma

Improvements to animal testing protocols could yield more useful clinical results

Study provides preliminary evidence that Parkinson's disease may start in the gut

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

Brain’s ability to rewire after injury can lead to long-term strains

New guidelines provide practical information on sudden unexpected death in epilepsy

Researchers discover new cellular mechanism that may cause multiple sclerosis

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Latest advances in antibody delivery mediated by rAAV for treatment of chronic and infectious diseases

People with multiple sclerosis begin to show symptoms much earlier than previously thought

Research shows potential way to limit damage to the brain caused by seizure disorder

Preliminary study reveals promising results of new treatment for progressive MS

Study provides evidence that virtual reality could help prevent falls in elderly people

Researchers develop sensor-equipped gloves to accurately measure muscle stiffness

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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