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Effective therapy enables immune system recovery in majority of children

Most children with HIV who have low levels of a key immune cell eventually recover levels of this cell after they begin treatment, according to a new study conducted by researchers at UCLA and other institutions in the U.S. and Brazil.

30 Mar 2015

Avoiding surgery may be better option for treating Type V AC joint injuries

Early surgery may not be the best treatment option for patients with Type V AC joint injuries, according to new research from Tripler Army Medical Center. The study, presented today at the American Orthopaedic Society for Sports Medicine's (AOSSM) Specialty Day, showed military personnel returned to duty faster when surgery was not performed.

30 Mar 2015

Synageva announces submission of Kanuma application to Cofepris for treatment of LAL Deficiency

Synageva BioPharma Corp., a biopharmaceutical company developing therapeutic products for rare disorders, announced today the submission to the Comisión Federal para la Protección contra Riesgos Sanitarios in Mexico for Kanuma as a treatment for patients with lysosomal acid lipase deficiency (LAL Deficiency), a rare genetic disease with significant morbidity and early mortality.

30 Mar 2015

Society for Reproductive Investigation awards two top honors to Dr. Ayman Al-Hendy

Dr. Ayman Al-Hendy, an obstetrician-gynecologist and molecular biologist at the Medical College of Georgia at Georgia Regents University and GRHealth, has received two top honors from the Society for Reproductive Investigation.

30 Mar 2015

MTI Expo 2015 to focus on engineering requirements in the medical technology sector

April 29-30, Ricoh Stadium, Coventry sees the next edition of the Med-Tech Innovation exhibition take place – engineering is the thread that runs through the whole show.

30 Mar 2015

$FLS could reduce healthcare costs associated with osteoporotic fractures$

FLS could reduce healthcare costs associated with osteoporotic fractures

Using a simulation model, Swedish researchers have shown that the implementation of Fracture Liaison Services (FLS) could considerably reduce the human and healthcare costs associated with osteoporotic fractures. The results from the model were presented today at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases in Milan.

30 Mar 2015

Study compares cost, benefits, complications of uterine-sparing treatments for fibroids

The relative cost, benefits, and complications of three minimally invasive techniques for reducing or eliminating symptomatic uterine fibroids are being compared in women who don't have cancer and want to preserve their uterus.

30 Mar 2015

Naldemedine meets primary and secondary endpoints in phase III study for OIC treatment

Naldemedine, an investigational peripherally acting mu-opioid receptor antagonist (PAMORA) under development by Shionogi & Co., Ltd., met its primary and secondary endpoints in a phase III study (COMPOSE I) for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain receiving opioid therapy.

30 Mar 2015

MDC scientists find solution to increase efficiency of precise genetic modifications

CRISPR-Cas9 is a powerful new tool for editing the genome. For researchers around the world, the CRISPR-Cas9 technique is an exciting innovation because it is faster and cheaper than previous methods. Now, using a molecular trick, Dr. Van Trung Chu and Professor Klaus Rajewsky of the Max Delbrück Center for Molecular Medicine Berlin-Buch and Dr. Ralf Kühn, MDC and Berlin Institute of Health, have found a solution to considerably increase the efficiency of precise genetic modifications by up to eightfold.

30 Mar 2015

Researchers evaluate decision aids for patient's choice of localised prostate cancer treatment

Doctors strive to make treatment decisions together with their patients - but is the decision really shared? According to adjunct professor Kari Tikkinen, shared decision-making isn't easy, and clinicians need help. The international research group led by Tikkinen has studied the decision aids for treatment choice of localised prostate cancer

30 Mar 2015

Experimental nanoparticle therapy speeds healing of all sorts of wounds

An experimental therapy developed by researchers at Albert Einstein College of Medicine of Yeshiva University cut in half the time it takes to heal wounds compared to no treatment at all. Details of the therapy, which was successfully tested in mice, were published online in the Journal of Investigative Dermatology.

30 Mar 2015

Penn State surgeon provides guidelines for diagnosis, management of endometriosis

Endometriosis is difficult to diagnose, with women often being told for years that they are experiencing their 'normal period.' According to the Endometriosis Foundation of America, it affects one in ten women.

30 Mar 2015

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

According to our understanding, mitochondria undergo cycles of fusion-fission, i.e. they divide within the constraints of a cell and, upon cell division, each of the two daughter cells gets its ‘share’ of mitochondria.

29 Mar 2015

Moffitt researchers use integrative approaches to study cancer heterogeneity

Moffitt Cancer Center researchers are using integrative approaches to study cancer by combining mathematical and computational modeling with experimental and clinical data. The use of integrative approaches enables scientists to study and model cancer progression in a manner that conventional experimental systems are unable to do.

29 Mar 2015

AACR to honor Lewis C. Cantley with Princess Takamatsu Memorial Lectureship

The American Association for Cancer Research will honor Lewis C. Cantley, PhD, with the ninth annual Princess Takamatsu Memorial Lectureship at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22.

29 Mar 2015

NCCC at Dartmouth designated again as Comprehensive Cancer Center by NCI

The National Cancer Institute has renewed its Cancer Center Support Grant to Norris Cotton Cancer Center at Dartmouth, continuing NCCC's designation as a Comprehensive Cancer Center.

29 Mar 2015

Radiation resistance in leukemia can be overcome by using new precision medicine, say researchers

A team of researchers led by Fatih M. Uckun, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles and Professor at the University of Southern California Keck School of Medicine has determined that radiation resistance in leukemia can be overcome by using an engineered protein they recently designed and developed as a new precision medicine against leukemia.

27 Mar 2015

Roseroot extract may be beneficial for treating major depressive disorder

Rhodiola rosea (R. rosea), or roseroot, may be a beneficial treatment option for major depressive disorder (MDD), according to results of a study in the journal Phytomedicine led by Jun J. Mao, MD, MSCE, associate professor of Family Medicine, Community Health and Epidemiology and colleagues at the Perelman School of Medicine of University of Pennsylvania.

27 Mar 2015

apceth begins Agenmestencel-T Phase II clinical trial in gastrointestinal cancer patients

apceth, a global leader in engineered cell therapies, today announced the successful completion of the Phase I and initiation of the Phase II part of its ongoing monocentric Phase I/II clinical trial TREAT-ME 1 with the engineered cell therapeutic product Agenmestencel-T, at the Klinikum Grosshadern in Munich.

27 Mar 2015

Regeneron announces FDA approval of EYLEA (aflibercept) Injection for diabetic retinopathy

Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has approved EYLEA (aflibercept) Injection for the treatment of diabetic retinopathy in patients with diabetic macular edema (DME). In 2014, the FDA granted EYLEA Breakthrough Therapy designation and Priority Review for the treatment of diabetic retinopathy in patients with DME.

27 Mar 2015

Therapy News and Research

Effective therapy enables immune system recovery in majority of children

Avoiding surgery may be better option for treating Type V AC joint injuries

Synageva announces submission of Kanuma application to Cofepris for treatment of LAL Deficiency

Society for Reproductive Investigation awards two top honors to Dr. Ayman Al-Hendy

MTI Expo 2015 to focus on engineering requirements in the medical technology sector

FLS could reduce healthcare costs associated with osteoporotic fractures

Study compares cost, benefits, complications of uterine-sparing treatments for fibroids

Naldemedine meets primary and secondary endpoints in phase III study for OIC treatment

MDC scientists find solution to increase efficiency of precise genetic modifications

Researchers evaluate decision aids for patient's choice of localised prostate cancer treatment

Experimental nanoparticle therapy speeds healing of all sorts of wounds

Penn State surgeon provides guidelines for diagnosis, management of endometriosis

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

Moffitt researchers use integrative approaches to study cancer heterogeneity

AACR to honor Lewis C. Cantley with Princess Takamatsu Memorial Lectureship

NCCC at Dartmouth designated again as Comprehensive Cancer Center by NCI

Radiation resistance in leukemia can be overcome by using new precision medicine, say researchers

Roseroot extract may be beneficial for treating major depressive disorder

apceth begins Agenmestencel-T Phase II clinical trial in gastrointestinal cancer patients

Regeneron announces FDA approval of EYLEA (aflibercept) Injection for diabetic retinopathy

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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