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Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

Mutations in the MAGEL2 gene, which cause Schaaf-Yan syndrome (SYS) —an ultra-rare disease that affects neuronal and cognitive development— generate truncated, non-functional proteins that tend to accumulate in the cell nucleus.

8 May 2024

Examining the causal link between long-term PM1 exposure and hypertension hospitalization risk

Hypertension is among the leading cardiovascular diseases. Despite extensive research, evidence concerning the relationship between long-term exposure to ambient particulate matter and hypertension remains limited and inconsistent, particularly with regard to submicron particulate matter (PM1).

8 May 2024

Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

A recent study published in The New England Journal of Medicine investigated the potential use of gene editing to correct a congenital retinal degeneration called CEP290 that causes early-onset vision loss.

8 May 2024

New technique enables detailed mapping of proteins in individual cells

Researchers from Karolinska Institutet, together with Pixelgen Technologies, have developed and applied a technique that makes it possible to map proteins in individual cells in a completely new way, according to a new study in Nature Methods.

8 May 2024

FAU researchers receive grants to tackle Alzheimer's disease

Three Florida Atlantic University researchers at the forefront of Alzheimer's disease (AD) research have each received a $350,000 grant from the Florida Department of Health's "Ed and Ethel Moore Alzheimer's Disease Research Program."

8 May 2024

THC detected in breast milk of cannabis-using mothers, study shows

When breastfeeding mothers in a recent study used cannabis, its psychoactive component THC showed up in the milk they produced.

8 May 2024

Intermittent fasting halts liver disease progression and reduces cancer risk

Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists from the German Cancer Research Center (DKFZ) and the University of Tübingen have now shown in mice that intermittent fasting on a 5:2 schedule can halt this development.

8 May 2024

Meta-analysis unveils connection between insulin-dependent diabetes and eating disorders

One in four patients with insulin-dependent diabetes aged 16 years and older also exhibit some kind of eating disorder symptoms, according to a recent meta-analysis conducted at the University of Eastern Finland.

8 May 2024

Mathematical microscope sheds light on efficient memory formation even during sleep

UCLA Health researchers have discovered a mechanism that creates memories while reducing metabolic cost, even during sleep.

8 May 2024

Compound 12: A promising candidate for heart failure therapy with reduced glucose-lowering activity

Prior research showed that thoughtful structural modifications can dissociate the anti-heart failure activity from glucose-lowering effects.

8 May 2024

New family of compounds shows promise as treatment for parasitic worms

An international team led by researchers at the University of Toronto has found a family of natural compounds with potential as new and more effective treatments for parasitic worms.

8 May 2024

Study sheds new light on the links between infections with inflammation and empathy for pain

When people are ill, they feel less empathy for others than when they are healthy. This has been confirmed by a study conducted by Ruhr University Bochum and the University of Duisburg-Essen, Germany.

8 May 2024

Pressure to be "perfect" leads to unhealthy impacts on both parents and children, study finds

Is the status of "perfect parent" attainable? Researchers leading a national dialogue about parental burnout from The Ohio State University College of Nursing and the university's Office of the Chief Wellness Officer say "no," and a new study finds that pressure to try to be "perfect" leads to unhealthy impacts on both parents and their children.

8 May 2024

Research News and Research

Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

Examining the causal link between long-term PM1 exposure and hypertension hospitalization risk

Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

New technique enables detailed mapping of proteins in individual cells

FAU researchers receive grants to tackle Alzheimer's disease

THC detected in breast milk of cannabis-using mothers, study shows

Intermittent fasting halts liver disease progression and reduces cancer risk

Meta-analysis unveils connection between insulin-dependent diabetes and eating disorders

Mathematical microscope sheds light on efficient memory formation even during sleep

Compound 12: A promising candidate for heart failure therapy with reduced glucose-lowering activity

New family of compounds shows promise as treatment for parasitic worms

Study sheds new light on the links between infections with inflammation and empathy for pain

Pressure to be "perfect" leads to unhealthy impacts on both parents and children, study finds

Gene linked to intellectual disability can regulate learning and memory

Novel head-mounted device shows promise in alleviating depression symptoms

High salt consumption linked to 40% higher stomach cancer risk

They were shot at the super bowl parade — and might have bullets in their bodies forever

Forget ringing the button for the nurse. Patients now stay connected by wearing one.

Study identifies strong link between red, processed meat intake and severe kidney damage in diabetic women

Health impacts and demographic inequities from nitrogen dioxide emissions in US homes using gas and propane stoves

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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Bringing real-time analytics to downstream bioprocess monitoring

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Evaluating new approaches for rare disease genomics