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Antidotes effective for treating acute liver failure patients in early stages of disease

The antidote for acute liver failure caused by acetaminophen poisoning also can treat acute liver failure due to most other causes if given before severe injury occurs, UT Southwestern Medical Center researchers and their colleagues at 21 other institutions have found.

8 Oct 2009

Researchers engineer antidotes for blood-thinner aptamers

Imagine a surgical patient on a blood-thinning drug who starts bleeding more than expected, and an antidote that works immediately - because the blood thinner and antidote were designed to work together. Researchers at Duke University Medical Center have engineered a way to do this for an entire, versatile class of drugs called aptamers and published their findings in Nature Medicine.

4 Oct 2009

MicroDose initiates Phase 1 clinical trial investigating the pharmacokinetics of atropine inhalation

MicroDose Therapeutx Inc. (formerly MicroDose Technologies) today announced that it has initiated a Phase I study at the University of Pittsburgh Medical Center with atropine sulfate delivered from the MicroDose proprietary dry powder inhaler (DPI). The study is a further step in the development program for an atropine inhaler to treat nerve agent poisoning in military and civil defense applications.

24 Sep 2009

Cyanide toxicity in smoke inhalation victims

"If commercial flying had as many civilian fatalities as those relating to smoke and fire, there would be a public revolt," said Rob Schnepp, CPTC president and assistant chief of special operations for the Alameda County Fire Department in California. "The numbers aren't going down, and this tells me that we aren't addressing the problem adequately.

18 Aug 2009

Akorn reports Q2 2009 financials

Akorn, Inc. (NASDAQ:AKRX) a specialty pharmaceutical company, today reported financial results for the second quarter ended June 30, 2009.

11 Aug 2009

Dodd stretched thin on finance and health roles

Critics are saying that Sen. Chris Dodd, D-Conn., cannot handle his role in financial regulatory reform while he sits in for ailing Sen. Edward Kennedy on the House's health committee, Politico reports.

23 Jun 2009

Many key lawmakers hold stakes in health industry

"Almost 30 key lawmakers helping draft landmark health-care legislation have financial holdings in the industry, totaling nearly $11 million worth of personal investments in a sector that could be dramatically reshaped by this summer's debate," The Washington Post reports.

15 Jun 2009

Stem cells could halt osteoporosis, promote bone growth

While interferon gamma sounds like an outer space weapon, it's actually a hormone produced by our own bodies, and it holds great promise to repair bones affected by osteoporosis.

4 Mar 2009

Health IT associated with better outcomes, lower costs

Patients at Texas hospitals that have automated some aspects of their health information systems appear to have fewer complications, lower death rates and reduced costs, according to a report in the January 26 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

27 Jan 2009

Party drug GHB a growing problem in Australia

Drug experts say use of the party drug GHB has escalated over the last four years and this is a cause for concern.

16 Jun 2008

Scientists determine drug target for the most potent botulinum neurotoxin

Botulinum neurotoxin - responsible for the deadly food poisoning disease botulism and for the beneficial effects of smoothing out facial wrinkles - can also be used as a dreaded biological weapon. When ingested or inhaled, less than a billionth of an ounce can cause muscle paralysis and eventual death. Although experimental vaccines administered prior to exposure can inhibit the destructive action of this neurotoxin - the most deadly protein known to humans - no effective pharmacological treatment exists.

29 Apr 2008

Humble cup of tea inhibits anthrax

A cup of black tea could be the next line of defence in the threat of bio-terrorism according to new international research.

13 Mar 2008

PNG black market in snake venom means over 600 die needlessly

Recent exposure by the Australian media has revealed that more than 600 people die needlessly in Papua New Guinea (PNG) from snake bites each year because corruption keeps stocks of anti-venom so low.

21 Feb 2008

Treatment with N-acetylcysteine is associated with better outcomes for children with liver failure

A new retrospective study on the effects of N-acetylcysteine (NAC) on children with acute liver failure not caused by acetaminophen poisoning has found that the treatment was associated with a shorter hospital stay, higher incidence of liver recovery, and better survival after transplantation.

4 Jan 2008

New fast-acting antidote to cyanide poisoning

University of Minnesota Center for Drug Design and Minneapolis VA Medical Center researchers have discovered a new fast-acting antidote to cyanide poisoning.

28 Dec 2007

Merck Serono's Cyanokit approved in Europe

Merck Serono, a division of Merck KGaA, announced today that the European Commission has granted marketing authorization for its product Cyanokit (active substance: hydroxocobalamin) for the treatment of known or suspected cyanide poisoning in both adults and the pediatric population.

3 Dec 2007