DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

New method could provide additional insight into brain tumors

A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the most effective treatments.

19 Jan 2021

Researchers identify biomarkers in sperm for paternal offspring autism susceptibility

Biomarkers in human sperm have been identified that can indicate a propensity to father children with autism spectrum disorder.

11 Jan 2021

Epigenetic modulators have a rapid antidepressant-like effect, study shows

Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants.

4 Jan 2021

Study clarifies the effect of aging on hematopoietic stem cells

By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem cells.

24 Dec 2020

Deep Longevity releases first AI-powered psychological aging clocks

Today, Deep Longevity, a company developing artificial intelligence to track human aging and extend productive longevity, released the first AI-powered psychological aging clocks to analyze and interpret psychosocial factors in the context of aging.

16 Dec 2020

Texas Biomed to investigate the effects of cannabinoids on HIV-associated neurocognitive disorder

The National Institutes of Health (NIH) awarded Professor Mahesh Mohan, D.V.M., Ph.D., and collaborators more than $3.5 million over five years to investigate the effects of cannabinoids on Human Immunodeficiency Virus (HIV) associated neurocognitive disorder (HAND).

11 Dec 2020

Study describes novel aging clock trained to predict human age

Deep Longevity, a Hong-Kong based longevity startup, has published their research on the epigenetics of aging in the Aging and Disease journal.

9 Dec 2020

Study elucidates the link between oxytocin gene methylation and parental empathy

Parenting behavior is deeply linked to the ability to empathize with one’s children. Thus, to better understand why certain parents react to certain situations in a certain way, it is crucial to gain insight into how empathy is shaped.

8 Dec 2020

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

An analysis of lung tissues from patients with different types of pulmonary fibrosis - including cases triggered by COVID-19 - has revealed a promising molecular target to ameliorate the chronic and irreversible disease.

5 Dec 2020

TB researchers uncover crucial clue that explains antibiotic resistance in bacteria

For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a matter of weeks to months.

18 Nov 2020

Researchers use single-cell analysis to assess effects of aging on mice’s egg cells

Using the power of single-cell analysis, researchers at the Babraham Institute have assessed the effects of age on egg cells (oocytes) in mice, particularly looking to identify genomic and epigenetic factors that relate to reduced developmental competence.

18 Nov 2020

Accelerated biological aging not a risk factor for severe COVID-19, say researchers

A new study conducted by researchers at RWTH Aachen University in Germany has found no evidence to support the hypothesis that severe outcomes in cases of coronavirus disease 2019 (COVID-19) may be linked to accelerated biological aging.

17 Nov 2020

Study indicates the role of Polβ enzyme in cognitive development

It's a fact of life that things break down. And when they do, whether it's your car, the roof, or a blocked artery, there are people who we can call to help with the repairs.

11 Nov 2020

Consumption of tree nuts impacts sperm DNA methylation

Many environmental and lifestyle factors have been implicated in the decline of sperm quality, with diet being one of the most plausible factors identified in recent years.

9 Nov 2020

Improved diet and more physical activity during pregnancy modifies infants’ DNA

A new study has shown pregnant women with obesity could reduce the health risks for their infants through improved diet and more physical activity.

6 Nov 2020

Inflammasome may play a key role in triggering immune response to cancer

The inflammasome — a protein signaling network that is activated to rid the body of virus or bacteria-infected cells — may play an important role in triggering an immune response to cancer and causing an existing class of drugs to work better against cancers.

27 Oct 2020

Distinct DNA methylation signature found in the cord blood of newborns diagnosed with ASD

A new study led by UC Davis MIND Institute researchers found a distinct DNA methylation signature in the cord blood of newborns who were eventually diagnosed with autism spectrum disorder (ASD).

22 Oct 2020

Scientists develop a way to accurately detect and monitor common pediatric brain cancer

A team of scientists at Texas A&M University, Baylor College of Medicine and Texas Children's Hospital have developed a way to more accurately both detect and monitor a common type of pediatric brain cancer, setting the stage for giving clinicians a real-time view into how the cancer responds to treatment.

21 Oct 2020

Researchers find distinct effects of adversity in the genomes of men than women born preterm

Researchers at McMaster University have found distinct effects of adversity early in life in the genomes of men compared to women who were born extremely preterm.