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New cryo-EM method may be able to shortcut a big step in modern vaccine development

Scientists at Scripps Research have devised a method that may be able to shortcut one of the big steps in modern vaccine development.

20 Jan 2022

Study identifies a new potential pathway for developing therapeutics against Epstein-Barr virus

A new study by researchers at The Wistar Institute, an international biomedical research leader in cancer, immunology, infectious disease, and vaccine development, has identified a new potential pathway for developing therapeutics that target Epstein-Barr virus (EBV).

19 Jan 2022

Rapid DNA sequencing technique used to diagnose rare genetic disease in short time

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours — a feat that's nearly unheard of in standard clinical care.

19 Jan 2022

Earth BioGenome Project moves from pilot projects to full-scale sequencing

A global effort to map the genomes of all plants, animals, fungi and other microbial life on Earth, is entering a new phase as it moves from pilot projects to full-scale production sequencing.

18 Jan 2022

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours - a feat that's nearly unheard of in standard clinical care.

13 Jan 2022

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

Biliary atresia is a rare disease that occurs when a delicate tree-like set of ducts that carry bile from the liver to the intestine becomes scarred and blocked. While some treatments can slow the damage, most children who develop biliary atresia will die without a liver transplant.

10 Jan 2022

Genomic variant may help predict which patients will experience chemotherapy-induced cardiotoxicity

A team of investigators have discovered a genomic variant that may help clinicians predict which patients will experience cardiotoxicity from a widely used chemotherapy drug, according to a Northwestern Medicine study published in Circulation.

3 Jan 2022

Strains - not species - of gut bacteria may provide better insights into the microbiome

Every day, the billions of bacteria that inhabit your digestive system change; the food you eat, medications you take, and germs you're exposed to make some bacteria flourish more than others.

24 Dec 2021

Cheap and accessible methods for genome sequencing will help tackle future pandemics

A worldwide consortium of scientists, led by the Earlham Institute and the University of Liverpool in the UK, mark a significant milestone in equipping researchers in low- and middle-income countries (LMICs) with cheap and accessible methods for sequencing large collections of bacterial pathogens - at a cost of less than $10USD per genome.

21 Dec 2021

Genome-wide ancient human DNA data from Sudan reveals new insights into the Nile Valley past

The first genome-wide ancient human DNA data from Sudan reveals new insights into the ancestry and social organization of people who lived more than 1,000 years ago in the Nile Valley, an important genetic and cultural crossroads.

20 Dec 2021

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

A recent study investigates histone mimicry as a mechanism by SARS-CoV-2 for disrupting epigenetic regulation to evade host cell responses to infection.

15 Nov 2021

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Scientists studying the most common and aggressive type of brain tumor in adults have discovered a new way of analyzing diseased and healthy cells from the same patient.

22 Oct 2021

Research reveals how daily circadian rhythms help to change heart function

A new study has shown how circadian rhythms in heart cells help to change heart function over the course of the day and may explain why shift workers are more vulnerable to heart problems.

18 Oct 2021

Study offers evolutionary insights into pineal color detection system of the lamprey

Most non-mammalian vertebrates have a color detection system in the pineal organ of the brain that is located in a single cell.

17 Sep 2021

$New tool can rapidly quantify T cell fraction and predict immunotherapy response$

New tool can rapidly quantify T cell fraction and predict immunotherapy response

Scientists at UCL and the Francis Crick Institute, London, have developed a new tool, which can rapidly estimate the number of T cells (immune cells) in a cancerous tumor; with T cell abundance helping predict a patient's response to immunotherapy, researchers are hopeful this could enable more targeted and effective cancer therapies.

8 Sep 2021

Research offers new insight into how to treat endometriosis

Endometriosis is a painful, chronic condition in which tissue from the uterus inappropriately grows outside the uterus.

26 Aug 2021

Next-Generation Sequencing and the Diagnosis of Disease

In this interview, Professor John Rossen talks about next-generation sequencing and it's implications for the diagnosis of disease.

From Tecan 4 Aug 2021

DNA sequencing from water and leech bloodmeals helps identify novel mammalian viruses

In a new scientific investigation headed by the German Leibniz Institute for Zoo and Wildlife Research, water from African and Mongolian waterholes as well as bloodmeals from Southeast Asian leeches were assessed for the ability to retrieve mammalian viruses without the need to find and catch the mammals.

28 Jun 2021

RAMBO can cut indexing times for huge DNA databases

Rice University computer scientists are sending RAMBO to rescue genomic researchers who sometimes wait days or weeks for search results from enormous DNA databases.