Genetic Engineering News and Research

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Zebrafish can provide genetic clues to the evolution of social behaviors in humans, domesticated species

Researchers at Queen Mary University of London have shown that zebrafish can provide genetic baz1b clues to the evolution of social behaviors in humans and domesticated species.

3 Jan 2023

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

Scientists have described the utility of gram-negative bacteria-derived outer membrane vesicles as vaccines and methods to expand their applications.

3 Jan 2023

Novel approach may prevent antibodies from triggering immune rejection of transplant cells

Researchers at UCSF have developed a novel, potentially life-saving approach that may prevent antibodies from triggering immune rejection of engineered therapeutic and transplant cells.

2 Jan 2023

Targeting defective tau proteins may be needed to treat Alzheimer’s patients

In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to be able to affect the course of this relentless, incurable disease.

26 Dec 2022

'Stem cell plasters' could revolutionize treatment for children with congenital heart disease

Researchers at the University of Bristol funded by the British Heart Foundation (BHF) have developed 'stem cell plasters' to revolutionize the way surgeons treat children living with congenital heart disease, so they don't need as many open-heart operations.

20 Dec 2022

Probiotic bacterium prevents neurodegeneration in animal model of ALS

A probiotic bacterium called Lacticaseibacillus rhamnosus HA-114 prevents neurodegeneration in the C. elegans worm, an animal model used to study amyotrophic lateral sclerosis (ALS).

20 Dec 2022

An epigenetic modification improves the defense against infections, research shows

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens.

9 Dec 2022

Scaling up the production of customized immune cells for drug development and testing

To prevent testing on animals and create even more precise ways of testing therapeutics, the pharmaceutical industry is increasingly turning to human immune cells.

1 Dec 2022

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Dec 2022

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

A change in the DNA code (mutation) of a gene that plays a key role in the brain's immune defenses may prevent related cells from clearing away protein-filled clumps, a new study in mice shows.

30 Nov 2022

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

A new study links a gene concentrated in the brain's cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer's disease.

30 Nov 2022

Miracles Start in the Lab: The quest to find a vaccine to cure AIDS

To commemorate World AIDS Day, News Medical spoke to Dr. Larry Corey, an internationally renowned expert in virology, immunology, and vaccine development, and the former president and director of Fred Hutch, about his work within the field of HIV/AIDS research and vaccine development.

30 Nov 2022

Upcycling polyethylene waste into pharmacologically useful natural products

Plastic waste is one of the most significant ecological and economic problems of our time. In the journal Angewandte Chemie, a research team has now introduced a chemical–biological method for upcycling polyethylene waste: catalytic cleavage is used to make carboxylic diacids that are subsequently converted into pharmacologically useful natural products by genetically engineered fungi.

30 Nov 2022

Exploring synthetic engineering of bacteriophages

In a new study, researchers demonstrated biological bacteriophage containment and synthetic engineering.

24 Nov 2022

CAR T therapy extends its reach beyond oncology

Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers.

23 Nov 2022

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

We speak to Matthew Dunne, Director for Drug Discovery at Micreos Pharmaceuticals, about the importance of creating new targeted antibacterial products.

22 Nov 2022

CAR T-cell therapy in colorectal cancer

Researchers assessed the efficacy of CAR T-cells in the immunotherapy of colorectal cancer.

21 Nov 2022

Study demonstrates unexpected electrical changes in first successful transplant of genetically-modified pig heart

Ten months after transplanting the first genetically-modified pig heart into a human patient, University of Maryland School of Medicine researchers continue to report on new findings from the landmark transplant.

14 Nov 2022

Novel drug could help to fight both COVID-19 and cancer

While vaccination can provide life-saving protection against COVID-19, scientists are still searching for ways to treat severe infections, including in people who cannot get vaccinated or in the event that dangerous new strains of the virus arise that could bypass vaccine protection.

14 Nov 2022

Serbia’s high-throughput genetic sequencing implementation | BGI Perspectives

On the occasion of the 17th International Conference of Genomics (ICG-17) jointly organized by BGI Genomics in Riga, Dr. Ivana Morić, a research professor from the Institute of Molecular Genetic and Genetic Engineering (IMGGE) at the University of Belgrade shared first-hand insights about the implementation of high-throughput sequencing in Serbia and its exciting future.

From BGI Genomics 14 Nov 2022

Genetic Engineering News and Research

Zebrafish can provide genetic clues to the evolution of social behaviors in humans, domesticated species

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

Novel approach may prevent antibodies from triggering immune rejection of transplant cells

Targeting defective tau proteins may be needed to treat Alzheimer’s patients

'Stem cell plasters' could revolutionize treatment for children with congenital heart disease

Probiotic bacterium prevents neurodegeneration in animal model of ALS

An epigenetic modification improves the defense against infections, research shows

Scaling up the production of customized immune cells for drug development and testing

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

Miracles Start in the Lab: The quest to find a vaccine to cure AIDS

Upcycling polyethylene waste into pharmacologically useful natural products

Exploring synthetic engineering of bacteriophages

CAR T therapy extends its reach beyond oncology

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

CAR T-cell therapy in colorectal cancer

Study demonstrates unexpected electrical changes in first successful transplant of genetically-modified pig heart

Novel drug could help to fight both COVID-19 and cancer

Serbia’s high-throughput genetic sequencing implementation | BGI Perspectives

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