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Oncologists find new biomarker for breast cancer having poor prognosis

With the support of the FWF, an oncologist found a biomarker for breast cancer having a poor prognosis and developed two viable methods to detect it in tissue samples.

22 Nov 2017

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

A popular drug commonly used to treat Alzheimer's disease has shown promise in laboratory and clinical trials for treating patients with sickle cell disease (SCD).

7 Nov 2017

UTHealth professor receives $2.6 million NIH award for brain research

The National Institutes of Health has presented its Maximizing Investigators' Research Award to Vasanthi Jayaraman, Ph.D., a professor of biochemistry and molecular biology with McGovern Medical School at The University of Texas Health Science Center at Houston. It is a $2.6 million, five-year award.

30 Oct 2017

New concise guide to pharmacology offers key information on major drug targets

The Concise Guide to PHARMACOLOGY 2017/18 is now available in the British Journal of Pharmacology. Published by Wiley on behalf of the British Pharmacological Society, the 440 page guide includes overviews of key properties for close to 1,700 human drug targets, identifies 3,500 ligands including more than 2,400 synthetic organic molecules and over 50 antibodies.

27 Oct 2017

Researchers uncover new molecular binding site that can influence electrical impulses in nerves

Researchers at Linköping University in Sweden have discovered a previously unknown molecular binding site that can influence electrical impulses in nerves.

27 Oct 2017

KU Leuven researchers identify new rapid response mechanism against bacterial infections

When bacteria enter our body, they kick-start a powerful immune response. But this chain of reactions doesn't fully account for our immediate responses. Researchers at KU Leuven, Belgium, show that so-called ion channels play a key role as 'first responders'.

23 Oct 2017

Dietary supplement could be promising therapeutic target for seizure disorders

Seizure disorders -- including epilepsy -- are associated with pathological hyperexcitability in brain neurons. Unfortunately, there are limited available treatments that can prevent this hyperexcitability.

13 Oct 2017

Fever in first trimester of pregnancy increases risk for birth defects, study shows

Fevers in a mother's first trimester of pregnancy increase the baby's risk for some heart defects and facial deformities such as cleft lip or palate, but exactly how this happens is unclear. Scientists have debated whether a virus or other infection causes the defects, or if fever alone is the problem.

12 Oct 2017

Duke researchers unravel how fever in early pregnancy increases risk for heart, facial birth defects

Researchers have known for decades that fevers in the first trimester of pregnancy increase risk for some heart defects and facial deformities such as cleft lip or palate. Exactly how this happens is unclear. Scientists have debated whether a virus or other infection source causes the defects, or if fever alone is the underlying problem.

10 Oct 2017

Brain shapes normal body patterning much earlier than previously thought

The brain plays an active and essential role much earlier than previously thought, according to new research from Tufts University scientists which shows that long before movement or other behaviors occur, the brain of an embryonic frog influences muscle and nerve development and protects the embryo from agents that cause developmental defects.

25 Sep 2017

IUPUI cell biologist receives $1.9 million grant to tackle age-related hearing loss

Cell biologist Benjamin J. Perrin of the School of Science at Indiana University-Purdue University Indianapolis is advancing knowledge of age-related hearing loss with the goal of informing possible therapeutic cell-regeneration approaches to the often-debilitating problem.

14 Sep 2017

Sodium channels play important role in keeping tiny lung capillaries from leaking, worsening pneumonia

Sodium channels in the cells that line the tiny capillaries in our lungs play an important role in keeping those capillaries from leaking and potentially worsening conditions like pneumonia, scientists report.

6 Sep 2017

Scientists use magnetic nanoparticles to trigger activity deep inside the brain

Scientists have used magnetism to activate tiny groups of cells in the brain, inducing bodily movements that include running, rotating and losing control of the extremities -- an achievement that could lead to advances in studying and treating neurological disease.

17 Aug 2017

CUMC researchers capture first snapshot of key brain receptor in action

Columbia University Medical Center researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, is involved in several important brain activities, including memory and learning.

24 Jul 2017

Ion Channel News and Research

Oncologists find new biomarker for breast cancer having poor prognosis

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

UTHealth professor receives $2.6 million NIH award for brain research

New concise guide to pharmacology offers key information on major drug targets

Researchers uncover new molecular binding site that can influence electrical impulses in nerves

KU Leuven researchers identify new rapid response mechanism against bacterial infections

Dietary supplement could be promising therapeutic target for seizure disorders

Fever in first trimester of pregnancy increases risk for birth defects, study shows

Duke researchers unravel how fever in early pregnancy increases risk for heart, facial birth defects

Brain shapes normal body patterning much earlier than previously thought

IUPUI cell biologist receives $1.9 million grant to tackle age-related hearing loss

Sodium channels play important role in keeping tiny lung capillaries from leaking, worsening pneumonia

Scientists use magnetic nanoparticles to trigger activity deep inside the brain

CUMC researchers capture first snapshot of key brain receptor in action

Discovery of ‘protective shield’ for b-cells could provide new option for treating diabetes

IBS researchers devise nanochannels for iodide transport in cell membranes

Salk scientist uses mathematical framework to better understand how cell types divide work

Scientists discover unexpected mechanism behind chronic nerve pain

Supercomputer study of the brain could lead to safer and more effective anesthetics

Researchers show how diesel fumes could potentially worsen underlying respiratory conditions

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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