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The Acoustics of the Brain: Random-access 3D Microscopy in Neuroscience

Máté Marosi and Zsolt Iván discuss the use of acousto-optic microscopes to study neural networks in the brain, from cell bodies to dendrites, to tiny spines.

From Femtonics Ltd. 17 Dec 2019

Study provides new insight into learning mechanisms of the cerebellum

In mere milliseconds trillions of chemical reactions ignite signals that travel across the billions of neurons in our brain. As we go through our daily lives and absorb new knowledge these neurons begin to modify themselves and change their signaling properties.

6 Dec 2019

Metrion and LifeArc extend neuroscience-focused ion channel drug discovery collaboration

Metrion Biosciences Limited, the specialist ion channel CRO and drug discovery company, and LifeArc, a leading UK independent medical research charity, today announced an extension of their neuroscience-focused ion channel drug discovery collaboration, following the success of the initial twelve-month agreement.

From Metrion Biosciences Limited 4 Dec 2019

New human colon-on-a-chip enables in vitro study of mucus physiology

We have a mutualistic but complicated relationship with the collection of microbes in our gut known as the intestinal microbiome.

3 Dec 2019

BGU researchers discover gene that causes nighttime atrial fibrillation

Genetic studies spanning three generations of a Persian Jewish family by researchers at Ben-Gurion University of the Negev. have identified a gene that causes nighttime atrial fibrillation (AFib).

18 Nov 2019

Understanding how pressure is regulated in the eye could lead to new treatments for glaucoma

Scientists in the University of Arizona Department of Physiology have identified a potential molecular mechanism that may hold the key to understanding how pressure is regulated in the eye.

14 Nov 2019

Cleveland Clinic researchers identify novel target for anti-fibrotic therapies

In a new study published in Science Signaling, Cleveland Clinic researchers have identified a novel target for new therapies that may help to treat or prevent a host of fibrotic conditions, which contribute to nearly half of overall mortality in the United States.

13 Nov 2019

Tulane virus needs intracellular calcium to replicate

Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome replication and building new viruses to invade other cells. The cells invaded by viruses also use calcium. They use it as signals to regulate many of the cells' own processes, but viruses can takeover cellular calcium signaling to satisfy their own needs.

13 Nov 2019

Scientists identify new mechanism for the development of Parkinson's disease

An international research team including scientists from the University of Cologne have identified a new mechanism for the development of Parkinson's disease, which could prove to be the starting point for the development of a more targeted therapy.

12 Nov 2019

How venom from marine cone snails can be used in pain therapy

Conotoxins are bioactive peptides found in the venom that marine cone snails produce for prey capture and defense.

4 Nov 2019

Columbia researchers capture new detailed images of a temperature-sensing molecule

Columbia University researchers have captured new detailed images of a temperature-sensing molecule in its open, intermediate, and closed states.

21 Oct 2019

More sensitive electrophysiology tools needed to study cancer cell populations

Bioelectricity of Cancer, a special issue of the peer-reviewed journal Bioelectricity, has just been published. Two promising discoveries are well delineated: an ultra-sensitive tool to detect cancer and a new therapeutic target for cancer immunotherapy.

9 Oct 2019

KIT researchers develop close-to-reality computer models of the heart

Digital simulations of human organs can be used to study the development of diseases and to customize therapies for patients.

4 Oct 2019

Researchers observe the working of protein associated with numerous health problems

For the first time, researchers have observed at the molecular level how a protein associated with numerous health problems works.

3 Oct 2019

UC Davis research team receives NIH grant to develop novel drugs for treating pain

A UC Davis research team, led by Vladimir Yarov-Yarovoy and Heike Wulff, will receive a $1.5 million grant from the National Institutes of Health to develop a novel class of peptides that are better at treating pain and don't have the side effects of opioids.

1 Oct 2019

Physiologists, researchers to discuss factors underlying cardiovascular disease at APS conference

International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

25 Sep 2019