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Engineered immune cells help eliminate severe bacterial infections effectively

Severe bacterial infections remain a major global health challenge because antibiotics alone often fail when the host immune system becomes dysfunctional.

17 Aug 2026

Immune signaling pathway protects newborn heart cells from injury

Researchers at the University Hospital of Bonn (UKB) and the University of Bonn have identified a previously unknown signaling pathway in the immune system that helps newborn heart cells survive and regenerate after injury.

17 Aug 2026

What happens to body fat when people follow the Eatwell Guide?

Higher adherence to the UK Eatwell Guide was associated with lower BMI, waist circumference, total body fat, and trunk fat in more than 156,000 UK Biobank participants. The associations persisted prospectively across demographic, physical activity, and genetic-risk groups, supporting the role of diet quality in weight management.

16 Aug 2026

Placental biology breakthrough could make biologic medicines safer during pregnancy

Biologic medicines have transformed the treatment of cancer, autoimmune diseases, migraine, inflammatory disorders and many other diseases.

14 Aug 2026

Würzburg researchers discover alternative approach to preventing thrombosis

Glycoprotein VI, or GPVI for short, is a surface receptor found exclusively on platelets and their precursor cells, megakaryocytes in the bone marrow.

14 Aug 2026

Advanced wastewater treatments may create unexpected environmental risks

Advanced wastewater treatment technologies are widely used to remove pollutants and pathogens before treated water is discharged or reused.

14 Aug 2026

Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis

Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence of estrogen receptor, progesterone receptor, and HER2 expression, rendering it insensitive to conventional endocrine and targeted therapies.

12 Aug 2026

Aging clock analysis identifies key genes in opioid dependence

A new research paper was published in Volume 18 of Aging on July 27, 2026, titled "Transcriptomic aging clock analysis identifies key genes in opioid dependence."

12 Aug 2026

Cannabis compounds may weaken glioblastoma response to chemotherapy and radiation

Several cannabinoids reduced chemotherapy- and radiation-induced apoptosis in glioblastoma cell models, with effects linked to reduced apoptotic priming, increased pro-survival signaling, and G1 cell-cycle arrest. The findings raise concern that cannabinoid exposure could interfere with some cancer treatments, although the results are limited to laboratory models and require in vivo and clinical validation.

12 Aug 2026

Genetic tool turns soft cancer cells into immune targets

Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a remarkable genetic tool that addresses one of the most persistent obstacles in cancer immunotherapy: the physical softness of tumors.

11 Aug 2026

New study identifies key pathway for delivering antisense cancer drugs

Antisense oligonucleotides (ASOs) have been proposed as a therapeutic approach to shut down the production of faulty proteins in a wide variety of diseases, including cancer.

11 Aug 2026

Semaglutide slows blood protein signature linked to future dementia risk

A post hoc analysis of 2,970 older SELECT participants found that semaglutide slowed worsening of a 25-protein blood signature that predicts future dementia risk. Over 104 weeks, semaglutide produced larger effects on modeled 5-year than 20-year dementia risk, but whether these biomarker changes translate into less cognitive decline or dementia remains unknown.

10 Aug 2026

Study links delayed Ewing sarcoma growth to reduced Trk and IGF1R pathway markers

A new research paper was published in Volume 17 of Oncotarget on August 7, 2026, titled "Delayed growth of SK-ES-1 Ewing sarcoma tumor xenografts is associated with reduced Trk and IGF1R pathway markers."

10 Aug 2026

Tirzepatide lowers heart attack and cardiovascular event risk in adults with type 2 diabetes

In a US cohort of 52,971 adults with type 2 diabetes and established atherosclerotic cardiovascular disease, tirzepatide initiation was associated with a lower one-year risk of major adverse cardiovascular events than sitagliptin. The benefit was driven mainly by lower myocardial infarction and all-cause mortality hazards, although the authors cautioned that mortality findings may be influenced by residual confounding.

10 Aug 2026

Single-dose psilocybin shows promise for treatment-resistant depression in NHS trial

A single 25-mg dose of psilocybin with psychological support was feasible to deliver within an NHS setting and produced large preliminary reductions in depressive symptoms among adults with treatment-resistant depression. The Phase 2 feasibility trial also found the treatment was generally well tolerated, although functional unblinding and expectancy effects mean larger, longer efficacy studies are needed.

10 Aug 2026

Why pulses could play a bigger role in healthy and sustainable diets

A narrative review finds that pulses may support gut and metabolic health through their fiber, protein, phytochemicals, and interactions with the gut microbiota, while offering a lower environmental footprint than many animal protein sources. Human evidence is strongest for selected cardiometabolic outcomes, while many microbiome and fermentation-related benefits remain supported mainly by animal and laboratory studies.

9 Aug 2026

New computer model connects brain chemistry to neural activity patterns

Researchers have developed a computer model of the human cortex that links its microscopic chemistry to its brain-wide patterns of activity, providing new evidence that regional differences in receptor density help shape how activity and information move across the brain.

7 Aug 2026

New review explores purinergic signaling pathways in osteoarthritis progression

A growing understanding of purinergic signaling is reshaping how scientists view osteoarthritis (OA), revealing an intricate communication network that influences joint inflammation, cartilage degeneration, bone remodeling, and chronic pain.

7 Aug 2026

Nicotine gum may make smokeless tobacco withdrawal easier to manage

A randomized trial found that 2 mg nicotine gum controlled craving, anxiety, and sleep problems more effectively than behavioral counselling during smokeless tobacco cessation. Although abstinence rates were numerically higher with nicotine gum, the differences were not statistically significant, highlighting the need for larger studies.

6 Aug 2026

IL-6 receptor blockers show promise for preventing MOGAD relapses

An international study led by Mayo Clinic researchers has identified interleukin-6 (IL-6) receptor blockers as a promising option for preventing relapses in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). MOGAD is a rare autoimmune neurological disorder that can cause vision loss, paralysis and other serious neurological complications.

6 Aug 2026