Small Molecules News and Research

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Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

A new study evaluates the efficacy of SNX-5422 as a post-exposure prophylactic treatment.

23 Nov 2021

Novel technique solves structure of the HIV capsid alone and in complex with host factors

A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.

21 Nov 2021

Researchers identify compounds that tackle fungal infections in a new way

Current medications aren't particularly effective against fungi. The situation is becoming more challenging because these organisms are developing resistance to antimicrobial treatments, just as bacteria are.

17 Nov 2021

Scientists use advanced microscopes to delve deeper into protein degradation process

Proteins are the building blocks of all living things. A vast amount research takes place on how these proteins are made and what they do, from enzymes that carry out chemical reactions to messengers that transmit signals between cells.

17 Nov 2021

Researchers identify new group of antibacterial molecules

Researchers at Karolinska Institutet, Umeå University, and the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic-resistant bacteria.

17 Nov 2021

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

10 Nov 2021

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Among the populations most significantly affected by COVID-19 are the elderly and patients with preexisting medical conditions including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease and chronic lung diseases like COPD and asthma.

8 Nov 2021

Milestone study uncovers genetic risk factors for spine osteoarthritis

Scientists from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed), contributing as part of the 'Genetics of Osteoarthritis (GO)' consortium to the world's largest study of over 800,000 individuals, have identified genetic risk factors - variants associated with SOX5 and CHST3 genes, key regulators of the development of the intervertebral discs, to be implicated in spine osteoarthritis (OA).

8 Nov 2021

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

A new study describes a new small molecule compound that has shown impressive safety, tolerability, and bioavailability against SARS-CoV-2.

7 Nov 2021

Novel drug improves management of ulcerative colitis

A new drug improved management of ulcerative colitis, according to a study published in the New England Journal of Medicine.

2 Nov 2021

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Systemic lupus erythematosis (SLE) is an autoimmune disease in which the immune system targets tissues of the body, causing widespread inflammation and affecting multiple organs such as the kidney and the brain.

27 Oct 2021

New study reveals how gut microbes may contribute to the beneficial effects of breastfeeding

It is widely acknowledged that breastfeeding benefits the health of infants. However, there is still a lack of solid evidence to document what happens in the gut of breastfed babies and how gut microbes may contribute to these beneficial effects.

25 Oct 2021

Scientists scan 110 natural compounds for SARS-CoV-2 antiviral potential

Phytochemicals are plant-derived molecules from medicinal plants that act as a prominent reservoir for treating a wide range of viral infections. In a new study, published in the journal Scientific Reports, scientists adopted a computational approach to identify Mpro inhibitors.

19 Oct 2021

TTUHSC investigator evaluates the potential of neurolysin as a therapeutic target for stroke

Ischemic stroke, the second leading cause of death worldwide, occurs when a vessel to the brain is blocked, reducing blood flow to the brain and depriving it of critical supplies of oxygen and nutrients.

8 Oct 2021

UTHSC receives $3.2 million to upgrade the Regional Biocontainment Laboratory

The University of Tennessee Health Science Center has been awarded $3.2 million from the National Institute of Allergy and Infectious Diseases (NIAID) to upgrade the equipment and infrastructure in the UTHSC Regional Biocontainment Laboratory (RBL) on the Memphis campus to enhance the university's research of infectious diseases, including COVID-19.

6 Oct 2021

Small Molecules News and Research

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

Novel technique solves structure of the HIV capsid alone and in complex with host factors

Researchers identify compounds that tackle fungal infections in a new way

Scientists use advanced microscopes to delve deeper into protein degradation process

Researchers identify new group of antibacterial molecules

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Milestone study uncovers genetic risk factors for spine osteoarthritis

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

Novel drug improves management of ulcerative colitis

Research reveals the microbial landscape of patients with systemic lupus erythematosus

New study reveals how gut microbes may contribute to the beneficial effects of breastfeeding

Scientists scan 110 natural compounds for SARS-CoV-2 antiviral potential

TTUHSC investigator evaluates the potential of neurolysin as a therapeutic target for stroke

UTHSC receives $3.2 million to upgrade the Regional Biocontainment Laboratory

A possible protective genetic polymorphism in COVID-19

SARS-CoV-2 entry inhibitors show antiviral activity

Discovery points toward a new strategy for treating Parkinson's disease

Discovery points toward a new strategy for treating Parkinson’s disease

Genetic capacity of the gut microbiome determines weight loss success or failure

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

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