Tau Protein News and Research

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Tau proteins are microtubule-associated proteins found in neurons in the brain.

Insight into cellular waste disposal could lead to new treatments for neurodegenerative diseases

A 'waste collection' tidies up our cells. If something does not go according to plan, serious diseases such as Alzheimer's or Parkinson's may develop.

20 Feb 2022

Regulating inflammation in Alzheimer's disease using a nanocleaner

In this new article publication from Acta Pharmaceutica Sinica B, authors Ting Lei, Zhihang Yang, Xue Xia, Yuxiu Chen, Xiaotong Yang, Rou Xie, Fan Tong, Xiaolin Wang, Huile Gao from Sichuan University, Chengdu, China and Macau University of Science and Technology, Macau, China discuss how nanocleaners can specifically penetrate the blood‒brain barrier at lesions to clean toxic proteins and regulate inflammation in Alzheimer's disease.

14 Feb 2022

Progression of Alzheimer's disease is linked to oxidative brain damage, research confirms

Increased oxidative damage is linked to neurodegenerative disorders such as Alzheimer's disease (AD). Even though the pathophysiology of AD has been widely investigated, the likely relationship between mitochondrial dysfunction and the disease remains largely unknown.

14 Feb 2022

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

In a new study, researchers investigated a link between the body’s inflammatory response to SARS-CoV-2 infection within the neuropathological pathways and tau hyperphosphorylation.

7 Feb 2022

Beta-amyloid deposits found in young patients with COVID-19

A new study describes the finding that patients of COVID-19 exhibit large amounts of focal β-amyloid deposits in their neocortical tissues.

25 Jan 2022

Tau mapping offers potential treatment targets and biomarkers for dementia and Alzheimer disease

By mapping all the protein interactions of a dementia-linked protein in the brain called Tau, a team of Weill Cornell Medicine investigators has created a road map for identifying potential new treatment targets for Alzheimer's disease and related dementia.

21 Jan 2022

New research identifies the cause of Alzheimer’s progression

In this interview, we spoke to Dr. Georg Meisl about his latest research that helped to identify the cause of Alzheimer’s progression.

13 Dec 2021

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses like human immunodeficiency virus (HIV).

9 Dec 2021

Brain injury markers associated with dysregulated immunological responses in COVID-19

Study shows that during hospitalization, patients with COVID-19 demonstrated elevated NfL and GFAP in a severity-dependant manner, as well as evidence of ongoing active brain injury 4 months later.

8 Dec 2021

Brain scans of athletes exposed to repetitive head impacts show white matter hyperintensities

Certain markers of injury to the brain's white matter, called white matter hyperintensities, can be seen on brain scans.

25 Nov 2021

Study offers new insight into the role of tau proteins in ALS pathogenesis

A team led by investigators at Massachusetts General Hospital has shown that people living with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, who carry a mutation in the C9orf72 gene exhibit elevated levels of tau and phosphorylated tau protein in the motor cortex region of the brain.

15 Nov 2021

International Alzheimer’s trial to evaluate a combination of drugs targeting two brain proteins

Trial participant Rachel Habiger meets in 2018 with Randall J. Bateman, MD, the director of the Dominantly Inherited Alzheimer Network Trials Unit at Washington University School of Medicine in St. Louis.

8 Nov 2021

MIT researchers identify link between MEF2 gene and cognitive resilience in older individuals

Many people develop Alzheimer's or other forms of dementia as they get older. However, others remain sharp well into old age, even if their brains show underlying signs of neurodegeneration.

3 Nov 2021

Specific amino acid supplementation could prevent the development of dementia

Dementia- a condition involving the extreme loss of cognitive function- is caused by a variety of disorders, including Alzheimer's disease.

22 Oct 2021

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer's disease pathology, a preclinical study led by University of South Florida Health (USF Health) researchers suggests.

5 Oct 2021

Researchers develop new mouse model for studying non-Demented with Alzheimer’s disease

Alzheimer's is a neurodegenerative disease that features the accumulation of the beta-amyloid peptide and Tau protein in the brain, which are associated with deficits in the neuronal connections and with dementia.

28 Sep 2021

Study establishes a new resource for exploring and understanding Alzheimer's disease

A study led by researchers from Brigham and Women's Hospital has established a new resource for exploring and understanding Alzheimer's disease (AD) on an individualized level.

2 Sep 2021

Research analyzes the role of RNA tags in Alzheimer’s disease

Understanding the role of tau protein in Alzheimer's disease (AD) has led to new ways to diagnose it as well as the creation of medicines now in clinical trials to treat it.

28 Aug 2021

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School of Medicine reveal in a paper published today in Nature Medicine.

26 Aug 2021

Quanterix Simoa® Technology Powers Breakthrough Alzheimer’s Disease Research Presented by Eli Lilly and Company at Alzheimer’s Association International Conference (AAIC) 2021

Ultra-sensitive Simoa® HD-X technology powers new findings that detect rapid reduction of plasma P-tau217 from donanemab, Lilly’s investigational antibody therapy for Alzheimer's disease at 12 weeks

From Quanterix 9 Aug 2021

Tau Protein News and Research

Further Reading

Insight into cellular waste disposal could lead to new treatments for neurodegenerative diseases

Regulating inflammation in Alzheimer's disease using a nanocleaner

Progression of Alzheimer's disease is linked to oxidative brain damage, research confirms

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

Beta-amyloid deposits found in young patients with COVID-19

Tau mapping offers potential treatment targets and biomarkers for dementia and Alzheimer disease

New research identifies the cause of Alzheimer’s progression

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Brain injury markers associated with dysregulated immunological responses in COVID-19

Brain scans of athletes exposed to repetitive head impacts show white matter hyperintensities

Study offers new insight into the role of tau proteins in ALS pathogenesis

International Alzheimer’s trial to evaluate a combination of drugs targeting two brain proteins

MIT researchers identify link between MEF2 gene and cognitive resilience in older individuals

Specific amino acid supplementation could prevent the development of dementia

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

Researchers develop new mouse model for studying non-Demented with Alzheimer’s disease

Study establishes a new resource for exploring and understanding Alzheimer's disease

Research analyzes the role of RNA tags in Alzheimer’s disease

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Quanterix Simoa® Technology Powers Breakthrough Alzheimer’s Disease Research Presented by Eli Lilly and Company at Alzheimer’s Association International Conference (AAIC) 2021

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