Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Unrecognized hypertension is common among emergency room patients, especially African Americans

Half of the study participants with high blood pressure reported that they were not under medical care for the condition. Further, the majority of this group stated that they had never been told that they had high blood pressure.

1 Sep 2005

New drug that selectively blocks immune responses protects kidneys after transplant

In an international clinical trial, a new drug that selectively blocks immune responses has proved as effective in preventing acute kidney transplant rejection as cyclosporine, the standard anti-rejection treatment.

24 Aug 2005

Decline in energy production by mitochondria appears to be a key problem leading to insulin resistance

A detectable decline in energy production by mitochondria - the organelles that are the cell's furnace for energy production - seems to be a key problem leading to insulin resistance, and thus to type 2 diabetes, according to studies by Howard Hughes Medical Institute researchers.

16 Aug 2005

Oral medications may control symptoms of Type II diabetes in children just as well as insulin injections

According to the medical records of 26 children diagnosed with the disease, oral medications reduced levels of a compound in the blood called hemoglobin A1C by an average of 2 percentage points.

15 Aug 2005

Study finds risk of death increases with peritoneal dialysis over hemodialysis

Researchers at Johns Hopkins have found that in people with end-stage kidney disease (ESRD), choosing peritoneal dialysis over hemodialysis increases their risk of dying by 50 percent.

2 Aug 2005

New research into muscle contraction will give scientists a better understanding of bladder problems and pain during childbirth

Professor Susan Wray, who heads the UK's top rated Department of Physiology, and Dr. Ted Burdyga, are studying muscles in the wall of the ureter, which connects the kidney to the bladder, to understand how muscles respond to signals in the body telling them to contract or relax.

1 Aug 2005

Nationwide survey reports a high rate of concern about body image in both boys and girls

A nationwide survey of more than 10,000 adolescents, published in the August issue of Pediatrics, reports a high rate of concern about body image in both boys and girls, and finds that adolescents with such concerns are much more likely to use hormones and dietary supplements to enhance their physique.

1 Aug 2005

Defect in the mechanics of motors that build tiny cellular hairs is the basis of Bardet-Biedl syndrome

A defect in the mechanics of motors that build tiny cellular hairs is the basis of a serious genetic disorder, according to researchers at UC Davis and Simon Fraser University, Canada.

1 Aug 2005

Diagnosing diabetes early saves lives

Australian Medical Association (AMA) President, Dr Mukesh Haikerwal, said today that while 520,000 Australians have been diagnosed with diabetes, there are probably as many again who remain undiagnosed, exposing them to serious complications caused by the disease, including kidney disease, heart attacks and eye problems.

19 Jul 2005

Sirna Therapeutics granted new UK patents

Sirna Therapeutics has announced that the United Kingdom (UK) Patent Office has granted the Company two additional short interfering RNA (siRNA) target patents. The first patent covers any siRNA with one or more chemical modifications targeting Vascular Endothelial Growth Factor (VEGF).

12 Jul 2005

Kidney disease associated with 'benign' prostate obstruction

Men who experience signs and symptoms of a prostate obstruction resulting from benign prostatic hyperplasia (BPH) are three times more likely than other men to develop chronic kidney disease, according to findings of a Mayo Clinic study published in this month's edition of Kidney International.

29 Jun 2005

If global efforts to prevent HIV/AIDS are to work long term, they must avoid suspicions of being unfair

Johns Hopkins infectious disease specialists who have spent more than two decades leading efforts to combat HIV and AIDS worldwide are warning that limited international relief supplies of antiretroviral therapies currently being distributed in Africa, Asia and the Caribbean will not get to those who can least afford to pay for them.

28 Jun 2005

Two common gene variations are associated with the risk for developing chronic kidney disease

Two common gene variations are associated with the risk for developing chronic kidney disease, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions. One variant increases risk and the other decreases risk with a similar effect in whites, African-Americans, diabetic and non-diabetic individuals.

14 Jun 2005

Fewer diabetics end up in hospital

According to new research from the U.S. Centers for Disease Control and Prevention (CDC), Americans with diabetes are less likely than they were a decade ago, to need hospitalization for serious complications such as kidney failure.

14 Jun 2005

Tight glucose control lowers CVD by about 50 percent in diabetes

A significantly lower risk of heart disease can now be added to the list of proven long-term benefits of tight glucose control in people with type 1 diabetes.

12 Jun 2005

Ruboxistaurin shows favorable effects on kidney damage and function in people with type 2 diabetes and nephropathy

Eli Lilly and Company today announced encouraging results from a one-year pilot study examining the effect of ruboxistaurin mesylate in persons with type 2 diabetes and kidney disease (also known as "diabetic nephropathy").

12 Jun 2005

Muraglitazar lowers blood glucose and helps dyslipidemia seen in diabetes

A novel compound provides long-term lowering of blood glucose levels and improves plasma lipids (fats) that are often a problem in people with type 2 diabetes -- all in a once-daily pill, according to a report presented today at the American Diabetes Association's 65th Annual Scientific Sessions.

12 Jun 2005

Nephropathy News and Research

Further Reading

Unrecognized hypertension is common among emergency room patients, especially African Americans

New drug that selectively blocks immune responses protects kidneys after transplant

Decline in energy production by mitochondria appears to be a key problem leading to insulin resistance

Oral medications may control symptoms of Type II diabetes in children just as well as insulin injections

Study finds risk of death increases with peritoneal dialysis over hemodialysis

New research into muscle contraction will give scientists a better understanding of bladder problems and pain during childbirth

Nationwide survey reports a high rate of concern about body image in both boys and girls

Defect in the mechanics of motors that build tiny cellular hairs is the basis of Bardet-Biedl syndrome

Diagnosing diabetes early saves lives

Sirna Therapeutics granted new UK patents

Kidney disease associated with 'benign' prostate obstruction

If global efforts to prevent HIV/AIDS are to work long term, they must avoid suspicions of being unfair

Two common gene variations are associated with the risk for developing chronic kidney disease

Fewer diabetics end up in hospital

Tight glucose control lowers CVD by about 50 percent in diabetes

Ruboxistaurin shows favorable effects on kidney damage and function in people with type 2 diabetes and nephropathy

Muraglitazar lowers blood glucose and helps dyslipidemia seen in diabetes

Patients with newly diagnosed type 2 diabetes should be screened for retinopathy

Link between PKC enzyme and kidney disease in diabetes confirmed

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

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