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Novel mutation identified in SARS-CoV-2 spike protein from Sweden

Researchers from Sweden and Brazil have identified a novel mutation in a strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) obtained from a patient in Stockholm, Sweden, in late April.

4 Aug 2020

Zika virus mutation responsible for quick spread, birth defects uncovered

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a Zika virus mutation that may be responsible for the explosive viral transmission in 2015/2016 and for the cause of microcephaly (babies with small heads) born to infected pregnant women.

3 Aug 2020

Extensive study of SARS-CoV-2 sequencing reveals six strains of the virus

The virus causing the COVID-19 pandemic, SARS-CoV-2, presents at least six strains. Despite its mutations, the virus shows little variability, and this is good news for the researchers working on a viable vaccine.

3 Aug 2020

School children unlikely to play a significant role in COVID-19 spread, says Finnish study

A study conducted by researchers in Finland suggests that children who are exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in schools are unlikely to transmit the virus further and play any significant role in the spread of coronavirus disease 2019 (COVID-19).

2 Aug 2020

New bivalent vaccine delivers robust cell-mediated and humoral immunity against SARS-CoV-2

In a groundbreaking bioRxiv study, US researchers demonstrate the capability of next-generation bivalent human adenovirus serotype 5 (hAd5) vaccine for inducing both cellular and humoral immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – using both an S protein sequence optimized for cell surface expression and a conserved nucleocapsid antigen designed to be transported to the endosomal subcellular compartment.

2 Aug 2020

Synthetic riboregulators detect SARS-CoV-2 genome parts in 40 minutes

By exploiting the tools of synthetic biology, the researchers from Turkey have successfully developed a de novo riboregulator system for rapidly detecting the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic material. Their paper is currently available on medRxiv preprint server.

2 Aug 2020

Managing cancer patients during COVID-19 pandemic

An ESMO interdisciplinary expert consensus paper on how to manage cancer patients during the COVID-19 pandemic has been published today in Annals of Oncology.

31 Jul 2020

New simple way of detecting COVID-19 in blood plasma

Even as the COVID-19 pandemic claims increasing numbers of patients, testing numbers are rising in most nations at the leading edge. However, the current reverse transcriptase-polymerase chain reaction (RT PCR) testing is often unavailable and takes up to several days for results to arrive.

31 Jul 2020

COVID-19 test kits offered by Carolina Liquid Chemistries granted FDA emergency use authorization

Carolina Liquid Chemistries, Corp., an innovative leader in clinical diagnostics and drug screening, is now offering test kits for COVID-19 that have been granted Emergency Use Authorization by the US Food and Drug Administration, pursuant to Section 564 of the Federal Food, Drug, and Cosmetic Act.

From Carolina Liquid Chemistries Corp. 29 Jul 2020

Inconsistent SARS-CoV-2 antibody results in nephrology workers

Using a broad spectrum of antibody tests the present study revealed inconsistent results for SARS-CoV-2 seroprevalence among asymptomatic individuals, while this was not the case among Covid-19 patients.

29 Jul 2020

Computed tomography can serve as effective tool for diagnosing COVID-19

The use of computed tomography in outpatient computed tomography centers (OCTC) is entirely consistent with the clinical data and global best practices. This is also an effective tool for diagnosing the coronavirus infection COVID-19

29 Jul 2020

Recurrent SARS-CoV-2 positives not infectious in discharged COVID-19 patients, says Chinese study

A new research paper from China published on the preprint server medRxiv* claims that recurrent positive results for SARS-CoV-2 are due to the presence of low levels of viral RNA fragments and not the shedding of infectious virus particles.

29 Jul 2020

UArizona aims to develop a device for quick and accurate detection of pathogens, biological threats

To better protect individuals serving on the front lines of battlefields or dealing with an event like the current COVID-19 health crisis or potential future pandemics, scientists at the University of Arizona College of Medicine - Phoenix are leading an effort to develop a device for easy, quick and accurate detection of pathogens and biological threats.

28 Jul 2020

New approach could enable wider adoption of COVID-19 testing for diagnosis in research laboratories

Clinician-scientists at Nanyang Technological University, Singapore's (NTU Singapore) Lee Kong Chian School of Medicine (LKCMedicine) have demonstrated a way to improve the speed, handling time and cost of COVID-19 laboratory tests.

27 Jul 2020

Pets show antibodies to SARS-CoV-2 in Italian study

A study shows that reverse transmission of SARS-CoV-2 is probable, with 3-4% of pets showing antibodies to the infection, though no virus was recovered.

24 Jul 2020

Analytik Jena Web Weeks – Analytik Jena launches new web seminar series for biomolecular applications, lab automation, and liquid handling

Analytik Jena is launching its brand new, English-language web seminar series “Analytik Jena Web Weeks” starting July 29, 2020. Until the end of the year, application specialists and product experts from Analytik Jena will present methods, technology solutions, and tips and tricks to make everyday laboratory work more efficient. Topics range from nucleic acid extraction, PCR, qPCR to liquid handling and laboratory automation.

From Analytik Jena US 23 Jul 2020

Analysis of the SARS-CoV-2 proteome via visual tools

Now, a new study published on the preprint server bioRxiv* in July 2020 shows how this can be advanced at a greater speed by combining experimental results with homology models obtained by high-throughput pipelines. This will help produce new hypotheses that will show novel druggable targets for effective drug development.

21 Jul 2020

Advanced cryo-EM imaging reveals high-resolution structure of viral RNA replication complex

For the first time, scientists at the Morgridge Institute for Research have generated near atomic resolution images of a major viral protein complex responsible for replicating the RNA genome of a member of the positive-strand RNA viruses, the large class of viruses that includes coronaviruses and many other pathogens.

20 Jul 2020

McGill researchers discover bacterial organelles involved in gene expression

Researchers at McGill University have discovered bacterial organelles involved in gene expression, suggesting that bacteria may not be as simple as once thought.

20 Jul 2020

Australian researches detect SARS-CoV-2 virus in wastewater from planes and cruise ships

Previous reports have shown that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), has been found in untreated wastewater. While the data is limited, there are no reported cases of a person becoming infected with the virus due to exposure to contaminated water.

20 Jul 2020

Polymerase News and Research

Novel mutation identified in SARS-CoV-2 spike protein from Sweden

Zika virus mutation responsible for quick spread, birth defects uncovered

Extensive study of SARS-CoV-2 sequencing reveals six strains of the virus

School children unlikely to play a significant role in COVID-19 spread, says Finnish study

New bivalent vaccine delivers robust cell-mediated and humoral immunity against SARS-CoV-2

Synthetic riboregulators detect SARS-CoV-2 genome parts in 40 minutes

Managing cancer patients during COVID-19 pandemic

New simple way of detecting COVID-19 in blood plasma

COVID-19 test kits offered by Carolina Liquid Chemistries granted FDA emergency use authorization

Inconsistent SARS-CoV-2 antibody results in nephrology workers

Computed tomography can serve as effective tool for diagnosing COVID-19

Recurrent SARS-CoV-2 positives not infectious in discharged COVID-19 patients, says Chinese study

UArizona aims to develop a device for quick and accurate detection of pathogens, biological threats

New approach could enable wider adoption of COVID-19 testing for diagnosis in research laboratories

Pets show antibodies to SARS-CoV-2 in Italian study

Analytik Jena Web Weeks – Analytik Jena launches new web seminar series for biomolecular applications, lab automation, and liquid handling

Analysis of the SARS-CoV-2 proteome via visual tools

Advanced cryo-EM imaging reveals high-resolution structure of viral RNA replication complex

McGill researchers discover bacterial organelles involved in gene expression

Australian researches detect SARS-CoV-2 virus in wastewater from planes and cruise ships

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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