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AstraZeneca’s new precision biologic gets FDA approval to treat severe eosinophilic asthma

AstraZeneca and its global biologics research and development arm, MedImmune, today announced that the US Food and Drug Administration has approved FASENRA (benralizumab) for the add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype.

14 Nov 2017

Analysis finds simple method to identify patients most likely to benefit from long-term canakinumab treatment

A new analysis seeks to answer the question of which patients are likely to gain the greatest cardiovascular benefit when treated with the anti-inflammatory agent canakinumab.

14 Nov 2017

University of Michigan and AstraZeneca partner to improve treatment for CKD patients

Patients with Chronic Kidney Disease (CKD) may benefit from a new collaboration between the University of Michigan and AstraZeneca who have partnered to develop a new therapeutic strategy for treatment.

10 Nov 2017

3D cultured spheroids could drive precision treatment for ovarian cancer

Honeycomb-like arrays of tiny, lab-grown cancers could one day help doctors zero in on individualized treatments for ovarian cancer, an unpredictable disease that kills more than 14,000 women each year in the United States alone.

9 Nov 2017

Scientists uncover mechanism that prevents tumor growth in melanoma

Natural Killer (NK) cells, lymphocytes of the innate immune system with strong cytotoxic activity, play a major role in the immune response against tumors.

8 Nov 2017

UA Cancer Center researchers delve deeper into benefits and harms of selenium supplementation

Personalized medicine -- health care tailored to the individual patient -- not only involves the use of prescription medications but vitamins and supplements as well.

8 Nov 2017

German scientists develop new nuclear medicine test to identify kidney transplant infection

German scientists have developed a novel nuclear medicine test that can determine whether a kidney transplant patient has developed infection in the transplanted tissue.

8 Nov 2017

Exposure to BPA during pregnancy may lead to long-lasting health problems in offspring

A chemical called bisphenol A -- BPA -- used in plastic packaging and in the linings of food and beverage cans, may be passed from a mother to her offspring during pregnancy and cause changes in the gut bacteria of the offspring, according to an international team of researchers.

8 Nov 2017

Novel approach could help predict how well patients respond to cancer treatment

A novel approach developed by researchers from the University of Leicester and the MRC Toxicology Unit could help to predict how well patients respond to drugs designed to fight various forms of cancer.

8 Nov 2017

Fitbit device selected to monitor health of 10k Americans

The national All of Us Research Program established by the White House in 2015 has selected Fitbit as the first wearable device that would provide information regarding the health of the Americans.

7 Nov 2017

FDA approves first targeted cancer treatment based on basket study

The US Food and Drug Administration has announced that it has approved the drug vemurafenib for the treatment of patients with BRAF V600-mutant Erdheim-Chester disease (ECD).

7 Nov 2017

FDG PET/CT imaging shows correlation between amount of cfDNA and cancer aggressiveness

Italian researchers have demonstrated a better way of determining the aggressiveness of tumors in patients with advanced non-small cell lung cancer (NSCLC).

7 Nov 2017

Researchers discover how traffic jam in intracellular sorting can cause tumor development

For tissues to cooperate and perform normal functions, cells need to know which way is up. When cells lose track of their orientation, they can start to grow out of control, and develop into cancer.

6 Nov 2017

Four main genes linked to survival of pancreatic cancer patients

Alterations in four main genes are responsible for how long patients survive with pancreatic cancer, according to a new study in JAMA Oncology.

3 Nov 2017

Researchers develop new, three-step system to eliminate colorectal cancer

Researchers at Memorial Sloan Kettering Cancer Center in New York City and Massachusetts Institute of Technology in Boston have developed a new, three-step system that uses nuclear medicine to target and eliminate colorectal cancer.

2 Nov 2017

Computers can alert doctors of acute kidney injury earlier to help save lives

Embedding a decision support tool in the hospital electronic health record increases detection of acute kidney injury, reducing its severity and improving survival, according to new research from the University of Pittsburgh and UPMC.

2 Nov 2017

Poor white matter health may contribute to persistent musculoskeletal pain in Gulf War veterans

A study from the William S. Middleton Memorial Veterans Hospital in Madison, Wisconsin, has shown that structural damage in the white matter of the brain may be linked to chronic musculoskeletal pain in Gulf War veterans.

1 Nov 2017

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

Several patients with recurring glioblastoma, a deadly brain cancer, survived for more than a year in a clinical trial believed to be the first to use comprehensive DNA and RNA sequencing of a patient's tumor to inform treatment for these patients in real-time.

27 Oct 2017

New targeted therapies help relieve symptoms of atopic dermatitis

If you think only infants suffer from eczema, think again. The uncomfortable, itchy rash that most people relate to babies and young children occurs frequently in adults.

27 Oct 2017

‘Precision Medicine’ may not always be so precise when applied to diverse populations, study says

Precision Medicine in oncology, where genetic testing is used to determine the best drugs to treat cancer patients, is not always so precise when applied to some of the world's more diverse populations, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope, and the Keck School of Medicine of the University of Southern California.

27 Oct 2017

Precision Medicine News and Research

AstraZeneca’s new precision biologic gets FDA approval to treat severe eosinophilic asthma

Analysis finds simple method to identify patients most likely to benefit from long-term canakinumab treatment

University of Michigan and AstraZeneca partner to improve treatment for CKD patients

3D cultured spheroids could drive precision treatment for ovarian cancer

Scientists uncover mechanism that prevents tumor growth in melanoma

UA Cancer Center researchers delve deeper into benefits and harms of selenium supplementation

German scientists develop new nuclear medicine test to identify kidney transplant infection

Exposure to BPA during pregnancy may lead to long-lasting health problems in offspring

Novel approach could help predict how well patients respond to cancer treatment

Fitbit device selected to monitor health of 10k Americans

FDA approves first targeted cancer treatment based on basket study

FDG PET/CT imaging shows correlation between amount of cfDNA and cancer aggressiveness

Researchers discover how traffic jam in intracellular sorting can cause tumor development

Four main genes linked to survival of pancreatic cancer patients

Researchers develop new, three-step system to eliminate colorectal cancer

Computers can alert doctors of acute kidney injury earlier to help save lives

Poor white matter health may contribute to persistent musculoskeletal pain in Gulf War veterans

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

New targeted therapies help relieve symptoms of atopic dermatitis

‘Precision Medicine’ may not always be so precise when applied to diverse populations, study says

Event guide: The 4th Precision Medicine in Inflammatory Bowel Disease Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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