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Navidea commences enrollment in NAV4694 Phase 2b study to detect erebral β-amyloid plaque

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that enrollment has commenced in its Phase 2b, open-label, safety and efficacy positron emission tomography imaging study of [18F]NAV4694 for detection of cerebral β-amyloid plaque in subjects diagnosed with Mild Cognitive Impairment.

28 Mar 2013

Study provides understanding of root causes of clinical variability in anxiety disorders

New findings from nonhuman primates suggest that an overactive core circuit in the brain, and its interaction with other specialized circuits, accounts for the variability in symptoms shown by patients with severe anxiety.

26 Mar 2013

Luminex collaborates with Merck to design companion diagnostic device for Alzheimer’s disease

WHITEHOUSE STATION known as MSD outside the United States and Canada, and Luminex Corporation have signed a collaboration and license agreement to develop a companion diagnostic device that will be evaluated to help screen patients for recruitment into Merck's clinical development program for MK-8931, a novel oral beta amyloid precursor protein site cleaving enzyme (BACE) inhibitor and Merck's lead investigational candidate for Alzheimer's disease (AD).

From Luminex 15 Mar 2013

Marsupials shed new light on functional morphology

When, how and why modern humans first stood up and walked on two legs is considered to be one of the greatest missing links in our evolutionary history. Scientists have gone to the far ends of the earth - and the wonderful creatures in it - to look for answers to why we walk the way we walk.

14 Mar 2013

Maxillary sinuses allow nose to change shape, say researchers

Pity the poor maxillary sinuses. Those bulbous pouches on either side of the human nose are known more for trapping mucus and causing sinus infections than anything else. They were thought to be an evolutionary relic of our distant past, with little known present value.

14 Mar 2013

Researchers uncover cellular-level detail of what happens when bone bears stress over time

From athletes to individuals suffering from osteoporosis, bone fractures are usually the result of tiny cracks accumulating over time -- invisible rivulets of damage that, when coalesced, lead to that painful break.

8 Mar 2013

Two novel radiolabeled small molecules can help detect prostate cancer

Two novel radiolabeled small molecules targeting prostate-specific membrane antigen (PSMA) have excellent potential for further development as diagnostic and therapeutic radiopharmaceuticals, according to research published this month in The Journal of Nuclear Medicine.

6 Mar 2013

Breakthrough study aims at developing first comprehensive model of fetal heart

Technology developed at The University of Nottingham has been used in a breakthrough study aimed at developing the first comprehensive model of a fully functioning fetal heart.

26 Feb 2013

Researchers create high resolution atlas of the heart with 3D images taken from 138 people

Researchers at Pompeu Fabra University (Spain) have created a high resolution atlas of the heart with 3D images taken from 138 people.

26 Feb 2013

CT angiography uncovers cardiovascular disease risk

Computed tomography angiography can warn of the likelihood for major adverse cardiovascular events in patients suspected of having coronary artery disease in the absence of medically modifiable risk factors, research shows.

25 Feb 2013

Non-tuberculous mycobacterial disease risk increased in COPD

Chronic respiratory disease is a significant risk factor for non-tuberculous mycobacterial pulmonary disease, results from a French study show.

25 Feb 2013

Lung cancer screening could avert 12,000 deaths each year in the US

Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers has the potential to avert approximately 12,000 lung cancer deaths each year in the United States.

25 Feb 2013

Possible alternative to biopsy discovered for renal cancer diagnosis

Combining positron emission tomography scanning with iodine-124 (124I)–girentuximab may offer an effective noninvasive method of diagnosing clear cell renal cell carcinoma in patients who present with a renal mass, US study results suggest.

20 Feb 2013

AMD risk alleles fail to predict treatment response

The major risk alleles that influence the development of age-related macular degeneration do not predict response to therapy for the condition, a substudy of the CATT trial indicates.

20 Feb 2013

High coronary artery calcium together with slow walking speed multiplies risk of mortality

High coronary artery calcium (CAC) together with slow walking speed multiplies the risk of mortality, reveals a new study published in the International Journal of Cardiology. Coronary artery disease is the leading cause of death worldwide and also a common cause of sudden death - heart attack often being the first sign of the disease.

20 Feb 2013

Immature malaria parasites more resistant to treatment with artemisinin

New research has revealed that immature malaria parasites are more resistant to treatment with key antimalarial drugs than older parasites, a finding that could lead to more effective treatments for a disease that kills one person every minute and is developing resistance to drugs at an alarming rate.

20 Feb 2013

Coronary computed tomography angiography effectively determines risk of heart attacks

Coronary computed tomography angiography (CCTA) is an effective tool for determining the risk of heart attacks and other adverse cardiac events in patients with suspected coronary artery disease but no treatable risk factors, such as high cholesterol or high blood pressure, according to a new study published online in the journal Radiology.

19 Feb 2013

Tomography News and Research

Navidea commences enrollment in NAV4694 Phase 2b study to detect erebral β-amyloid plaque

Study provides understanding of root causes of clinical variability in anxiety disorders

Luminex collaborates with Merck to design companion diagnostic device for Alzheimer’s disease

Marsupials shed new light on functional morphology

Maxillary sinuses allow nose to change shape, say researchers

Researchers uncover cellular-level detail of what happens when bone bears stress over time

Two novel radiolabeled small molecules can help detect prostate cancer

Breakthrough study aims at developing first comprehensive model of fetal heart

Researchers create high resolution atlas of the heart with 3D images taken from 138 people

CT angiography uncovers cardiovascular disease risk

Non-tuberculous mycobacterial disease risk increased in COPD

Lung cancer screening could avert 12,000 deaths each year in the US

Possible alternative to biopsy discovered for renal cancer diagnosis

AMD risk alleles fail to predict treatment response

High coronary artery calcium together with slow walking speed multiplies risk of mortality

Immature malaria parasites more resistant to treatment with artemisinin

Coronary computed tomography angiography effectively determines risk of heart attacks

Increase in thigh fat is predictive of mobility loss in otherwise healthy older adults

Optimal lung cancer screening nodule size questioned

Clot evacuation reduces perihematomal edema in hemorrhagic stroke

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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