Genes News and Research

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Scientists create first crystal structure of an intermediate particle in virus assembly

The structure, described February 8 in an advance online publication of the journal Nature , provides fresh insights into the elegant dance that viral proteins perform to create the infectious structure that causes all manner of misery and disease, say researchers.

8 Feb 2009

New genes involved in acute lymphoblastic leukemia play fundamental role in prognosis of the disease

The inactivity or "silence" of certain genes plays a fundamental role in the prognosis of acute lymphoblastic leukemia as well as in response to treatment, according to the results of research involving a team made up of specialists from the University Hospital of Navarra and the Center for Applied Medical Research at the same University of Navarra, as well as the Reina Sofía Hospital in Cordoba, Andalusia.

8 Feb 2009

Long-sought protein structure may help reveal how 'gene switch' works

The bacterium behind one of mankind's deadliest scourges, tuberculosis, is helping researchers at the Commerce Department's National Institute of Standards and Technology (NIST) and the Department of Energy's Brookhaven National Laboratory (BNL) move closer to answering the decades-old question of what controls the switching on and off of genes that carry out all of life's functions.

8 Feb 2009

Brain-derived neurotrophic factor protects key brain cells in Alzheimer's models

Memory loss, cognitive impairment, brain cell degeneration and cell death were prevented or reversed in several animal models after treatment with a naturally occurring protein called brain-derived neurotrophic factor (BDNF).

8 Feb 2009

Growth factor protects key brain cells in Alzheimer's models

8 Feb 2009

Discovery of direct link between vitamin D and MS susceptibility 'gene'

Researchers have found evidence that a direct interaction between vitamin D and a common genetic variant alters the risk of developing multiple sclerosis (MS).

8 Feb 2009

FDA approves orphan drug ATryn anticoagulant

The U.S. Food and Drug Administration has issued its first approval for a biological product produced by genetically engineered (GE) animals.

8 Feb 2009

Novel gene silencing platform

A team of researchers led by Rutgers' Samuel Gunderson has developed a novel gene silencing platform with very significant improvements over existing RNAi approaches.

8 Feb 2009

Extra copies of LIS1 gene carry extra risk

Is more of a good thing better? A gene known as LIS1 is crucial for ensuring the proper placement of neurons in the developing brain.

5 Feb 2009

New research may lead to new pharmacologic approaches to treating obesity

Scientists at the University of North Carolina at Chapel Hill School of Medicine have discovered a gene that when mutated causes obesity by dampening the body's ability to burn energy while leaving appetite unaffected.

5 Feb 2009

Research links photosynthesis genes to marine virus fitness

A recent Northeastern University study has shown, for the first time, the effect of individual genes on the fitness of a marine species at the ecosystem level.

5 Feb 2009

Molecule that suppresses immune response under study in type 1 diabetes

The idea is to teach the immune system of children at high risk for type 1 diabetes not to attack the insulin-producing cells of the pancreas.

5 Feb 2009

Researchers identify gene mutations that affect learning, memory in children

Mental deficiency is the most frequently occurring, yet least understood handicap in children.

5 Feb 2009

Scientists discover missing link in the way cells protect themselves against cancer

Cancer Research UK scientists have discovered a missing link in the way cells protect themselves against cancer, according to research published in Genes & Development.

5 Feb 2009

Genetic marker for insecticide resistance in mosquitoes identified

Research led by the Liverpool School of Tropical Medicine has identified the genetic basis for resistance to commonly-used insecticides in one of the major malaria-carrying mosquitoes in Africa.

5 Feb 2009

Bacteria are models of efficiency

The bacterium Escherichia coli, one of the best-studied single-celled organisms around, is a master of industrial efficiency.

5 Feb 2009

Disruption of circadian clock can suppress cancer growth

Researchers at the University of North Carolina at Chapel Hill have shown that disruption of the circadian clock - the internal time-keeping mechanism that keeps the body running on a 24-hour cycle - can slow the progression of cancer.

3 Feb 2009

New test predicts how breast cancer patients respond to chemotherapy

Researchers at the Swiss Institute of Bioinformatics and the Swiss National Center of Competence in Research in Molecular Oncology in Lausanne have developed a new test to predict how breast cancer patients respond to chemotherapy, which could help change how treatment is delivered in the future.

3 Feb 2009

Gene-targeting approach for herpes treatment

A new therapy being developed at the University of Florida could, in time, produce another weapon for the fight against herpes.

3 Feb 2009

Novel gene may cause restless legs syndrome in a large family

In 2005, a woman who had trouble sleeping asked Siong-Chi Lin, M.D., for help. Dr. Lin, a sleep disorders specialist at the Mayo Clinic campus in Florida, diagnosed restless legs syndrome.

3 Feb 2009