Immune System News and Research

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Study explains complex infection fighting mechanism

Yale School of Medicine researchers report in Nature Immunology how infection fighting mechanisms in the body can distinguish between a virus and the healthy body, shedding new light on auto immune disorders.

11 Jan 2006

Tobacco plant-derived vaccines safeguard against Yersinia pestis

Through an innovative feat of plant biotechnology and vaccine design, researchers in the Biodesign Institute at Arizona State University have successfully turned tobacco plants into vaccine production factories to combat the deadliest form

10 Jan 2006

Approval of first immune globulin for use beneath the skin

The U.S. Food and Drug Administration (FDA) has announced the approval of the first immune globulin product for subcutaneous injection for the prevention of serious infections in patients with Primary Immune Deficiency Diseases (PIDD).

10 Jan 2006

Sydney researchers explain how stress makes you sick

Garvan Institute scientists have discovered how a hormone, known as neuropeptide Y (NPY), can prevent our immune system functioning properly, paving the way for two new major opportunities for therapeutic intervention.

10 Jan 2006

Human Genome Sciences announces license agreement with Amgen

Human Genome Sciences has announced a license agreement with Amgen under which Amgen has acquired exclusive worldwide rights to develop and commercialize therapeutic biological products for human use based on a human gene discovered by Human Genome Sciences that may have potential applications in autoimmune diseases, immune deficiencies or suppression, and cancer.

10 Jan 2006

Loyola to study for first time IV medication for osteopenia and inflammatory bowel diseases

Researchers at the Osteoporosis and Metabolic Bone Disease Center and the Division of Gastroenterology at Loyola University Health System are studying a once-yearly, 15-minute infusion of an intravenous (IV) medication in patients with osteopenia (low bone mass) and inflammatory bowel diseases (IBD) that, if proven effective, may be considered the standard of treatment.

10 Jan 2006

Genetic mutation that protects against HIV increases the risk of West Nile Virus infection

A genetic mutation that protects against HIV increases the risk of developing clinical West Nile Virus infection, according to a new study appearing online on January 9th in The Journal of Experimental Medicine.

9 Jan 2006

Unorthodox vaccine could one day help to prevent or control HIV infection

Researchers at Baylor College of Medicine (BCM) in Houston have reason to believe their unorthodox vaccine could one day help to prevent or control HIV infection, according to a study published in today's edition of Public Library of Science Medicine.

6 Jan 2006

Researchers uncover new toxic mechanism in ALS - Lou Gehrig's disease

Exactly how ALS - Lou Gehrig's disease - damages motor neurons is one of medical science's lingering mysteries. At least six mishaps within cells appear to contribute to the death of the nerves that enable muscle movement, but nothing stands out as the key problem.

6 Jan 2006

New technique points to safer, more efficient vaccination

Researchers have demonstrated a technique that has the potential to reduce the toxicity of vaccines and to make smaller doses more effective, according to a study published in PLoS Pathogens.

6 Jan 2006

Largest post-mortem study of SARS deaths teaches scientists about the disease

Led by John Nicholls of Hong Kong University, researchers from Hong Kong and from Toronto (two of the cities worst affected by the 2003 SARS outbreak) joined forces for a large and detailed study of the bodies of 32 patients who had died from SARS.

6 Jan 2006

Taking an alternative approach to HIV vaccination

Researchers from Baylor College of Medicine have shown that switching off a molecule that helps regulate dendritic cells, specialized white blood cells that activate the immune system, could help the host fight HIV infection.

6 Jan 2006

Fruit bats a reservoir for Ebola virus

IRD researchers have succeeded in the first identification of bats as a potential natural reservoir of Ebola virus. Several epidemics of haemorrhagic fever have raged in the Republic of Congo and Gabon since 2001, hitting both humans and primates simultaneously.

6 Jan 2006

Scientists describe phenomenon in the human genome called transcription-induced chimerism

In the January issue of the journal Genome Research, two teams of scientists describe a widespread phenomenon in the human genome called transcription-induced chimerism (TIC), where two adjacent genes produce a single, fused RNA transcript.

6 Jan 2006

Scientists develop prototype drug to prevent osteoporosis based on cannabinoids produced by body

Substances produced in the body that act like those found in the cannabis plant help preserve bone density, according to researchers at the Hebrew University of Jerusalem.

6 Jan 2006

New model for the origin of rheumatoid arthritis

Rheumatoid arthritis (RA) is one of the most common systemic autoimmune diseases, and one of the least understood. Smoking is the major known environmental risk factor for RA, though little is known about the mechanisms involved.

6 Jan 2006

Caspase 8 gene halts spread of aggressive childhood cancer

A team of cancer researchers has shown that a gene commonly lost during neuroblastoma tumor formation, one of the most aggressive cancers in babies and children, is in fact a "metastasis suppressor" gene.

6 Jan 2006

New pathways linking liver disease to changes in the central nervous system

Liver disease is often associated with "sickness behaviors," such as malaise, listlessness, anorexia, difficulty concentrating, and fatigue. In cholestatic liver diseases (where bile production is impaired) such as primary biliary cirrhosis, fatigue occurs in up to 86 percent of patients.

5 Jan 2006

Brain's endocannabinoids protects neurons from inflammation

Some clinical studies have indicated that marijuana or its active cannabinoid ingredient alleviates symptoms of the inflammatory disease multiple sclerosis (MS).

5 Jan 2006