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Keynote 24 study explores investigational approach to treating lung cancer

Lung cancer impacts the lives of millions of people worldwide. In nearly 40 percent of people diagnosed with lung cancer, it has metastasized, or spread to other areas of the body, making it difficult to treat. Immunotherapy is a type of therapy that uses the body's own immune system to help fight cancer. Immunotherapy may help the body's immune system target cancer cells.

30 Apr 2015

ResMed launches Lumis series of noninvasive ventilation devices to manage respiratory stability of patients

ResMed today announced its Lumis series of noninvasive ventilation devices that combine personalized, simplified therapy with powerful wireless connected care capabilities. The Lumis series builds upon ResMed's legacy of innovation as a new option for patients with respiratory challenges who are not dependent on continuous ventilation.

From ResMed Corp 30 Apr 2015

HeartWare International's revenue increases 5% to $70.0 million in first quarter 2015

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced revenue of $70.0 million for the first quarter ended March 31, 2015, a five percent increase compared to $66.5 million in revenue for the same period of 2014.

30 Apr 2015

Neurocrine reports net loss of $1.2 million for first quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter ended March 31, 2015. For the first quarter of 2015, the Company reported a net loss of $1.2 million, or $0.01 loss per share, compared to a net loss of $11.8 million, or $0.17 loss per share, for the same period in 2014.

30 Apr 2015

OncoGenex provides update on Phase 3 ENSPIRIT trial evaluating custirsen for treatment of NSCLC

OncoGenex Pharmaceuticals, Inc. announced today it has filed an amendment with the U.S. Food and Drug Administration, as well as initiated filing with regulatory agencies in other countries, to amend the statistical design and analysis plan of its pivotal, international Phase 3 ENSPIRIT trial evaluating custirsen in the treatment of non-small cell lung cancer (NSCLC).

30 Apr 2015

Novel combination therapy shows promise in mouse models of advanced prostate cancer

Chemotherapy can be very effective against small prostate tumors. Larger prostate tumors, however, accumulate cells that suppress the body's immune response, allowing the cancer to grow despite treatment.

30 Apr 2015

Study finds that gene therapy can clip out genetic material associated with heart failure

Gene therapy can clip out genetic material linked to heart failure and replace it with the normal gene in human cardiac cells, according to a study led by researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

30 Apr 2015

Cytokine GM-CSF likely plays important role in MS

Multiple sclerosis (MS) is caused by immune cells that activate a cascade of chemicals in the brain, attacking and degrading the insulation that keeps neuronal signals moving. These chemicals, called cytokines, drive the inflammation in the brain, attracting more immune cells, and causing the debilitating disease marked by loss of neurological function.

30 Apr 2015

Adult survivors of preterm births at higher risk of developing COPD

Adult survivors of preterm births may have a lung capacity that resembles the healthy elderly or casual smokers by the time they reach their early 20s, according to a University of Oregon study.

30 Apr 2015

Patients with traumatic brain injuries need effective cognitive neuroscience-based therapies

Patients with traumatic brain injuries are not benefiting from recent advances in cognitive neuroscience research - and they should be, scientists report in a special issue of Current Opinion in Behavioral Sciences.

30 Apr 2015

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Blood-based biomarkers such as circulating tumor cells (CTCs), circulating free DNA (cfDNA), circulating tumor DNA (ctDNA) and microRNAs (miRNAs) are potential indicators for the tumor burden of patients living with cancer.

30 Apr 2015

Better interventions needed to improve outcomes in young breast cancer patients

Breast cancer that occurs in young women is likely to be more aggressive and to require more intensive types of therapy with increased risk of long-term treatment-related toxicities. The unique and significant challenges and psychosocial concerns that women under 40 years of age with breast cancer face are discussed in a special article published in Journal of Adolescent and Young Adult Oncology, a multidisciplinary peer-reviewed publication from, Mary Ann Liebert, Inc., publishers.

30 Apr 2015

TDF switch effective in Asian chronic HBV patients

Switching therapy to tenofovir disoproxil fumarate is effective in treatment-resistant chronic hepatitis B, show results from a cohort of Asian patients.

29 Apr 2015

Kidney damage unlikely with TDF monotherapy in chronic HBV patients

In patients with chronic hepatitis B virus infection, treatment with tenofovir disoproxil fumarate does not significantly increase the risk of developing renal dysfunction compared with entecavir treatment, a US team reports.

29 Apr 2015

Patients with adefovir-resistant HBV benefit from TDF monotherapy

Tenofovir disoproxil fumarate alone elicits a response comparable to that of TDF plus entecavir in heavily pretreated patients with chronic hepatitis B virus infection resistant to adefovir dipivoxil, research suggests.

29 Apr 2015

University of St. Augustine plans to bring Doctor of Physical Therapy program to Miami

The University of St. Augustine for Health Sciences plans to bring its Doctor of Physical Therapy program to Miami in fall 2015, pending accreditation and other regulatory approvals. The university, which has been a part of north Florida for more than 20 years, will open its new campus near the Dolphin Mall.

29 Apr 2015

Sangamo BioSciences to present data on ZFP Therapeutic platform at ASGCT meeting

Sangamo BioSciences, Inc. announced that data from clinical, preclinical and research-stage programs focused on the development of ZFP Therapeutics will be presented at the 18th Annual Meeting of the American Society of Gene and Cell Therapy

29 Apr 2015

UI orthopedics researchers working on injectable, bioactive gel that can repair cartilage damage

Knee injuries are the bane of athletes everywhere, from professionals and college stars to weekend warriors. Current surgical options for repairing damaged cartilage caused by knee injuries are costly, can have complications, and often are not very effective in the long run. Even after surgery, cartilage degeneration can progress leading to painful arthritis.

29 Apr 2015

Scientists identify new way to predict disease outcomes in people with rheumatoid arthritis

Arthritis Research UK-funded scientists at The University of Manchester have identified a new way in which genotyping can be used to predict disease outcomes among sufferers of rheumatoid arthritis.

29 Apr 2015

Lung cancer surgery patients at higher risk of developing venous thromboembolism

New evidence suggests that lung cancer surgery patients are at higher risk of developing venous thromboembolism, including deep vein thrombosis (DVT) and pulmonary embolism (PE), than previously thought, with elevated risks of complications or death. When thromboemboli occur, they may be asymptomatic or attributed to post-surgical pain or complications, and may reflect both the lung cancer itself as well as compromised lung function after surgery.

29 Apr 2015

Therapy News and Research

Keynote 24 study explores investigational approach to treating lung cancer

ResMed launches Lumis series of noninvasive ventilation devices to manage respiratory stability of patients

HeartWare International's revenue increases 5% to $70.0 million in first quarter 2015

Neurocrine reports net loss of $1.2 million for first quarter 2015

OncoGenex provides update on Phase 3 ENSPIRIT trial evaluating custirsen for treatment of NSCLC

Novel combination therapy shows promise in mouse models of advanced prostate cancer

Study finds that gene therapy can clip out genetic material associated with heart failure

Cytokine GM-CSF likely plays important role in MS

Adult survivors of preterm births at higher risk of developing COPD

Patients with traumatic brain injuries need effective cognitive neuroscience-based therapies

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Better interventions needed to improve outcomes in young breast cancer patients

TDF switch effective in Asian chronic HBV patients

Kidney damage unlikely with TDF monotherapy in chronic HBV patients

Patients with adefovir-resistant HBV benefit from TDF monotherapy

University of St. Augustine plans to bring Doctor of Physical Therapy program to Miami

Sangamo BioSciences to present data on ZFP Therapeutic platform at ASGCT meeting

UI orthopedics researchers working on injectable, bioactive gel that can repair cartilage damage

Scientists identify new way to predict disease outcomes in people with rheumatoid arthritis

Lung cancer surgery patients at higher risk of developing venous thromboembolism

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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