Immune System News and Research

RSS

Surprise discovery helps tackle rabies

In an unexpected discovery, scientists at Jefferson Medical College have found that a tiny change in a rabies virus protein can turn a "safe" virus extremely deadly. The finding has enabled the researchers to refine a vaccine they previously created against rabies in wildlife, making it safer and more effective.

5 Jan 2006

UCLA examines disease-versus-disease interactions

The knowledge that one disease may prevent the onset of another is not new. For example, the discovery that cowpox vaccines can prevent smallpox dates back to 1798.

5 Jan 2006

SOCS1 silencing could help enhance vaccines against HIV

Researchers from Baylor College of Medicine have shown that switching off a molecule that helps regulate dendritic cells, specialized white blood cells that activate the immune system, could help the host fight HIV infection.

4 Jan 2006

Technique to reduce the toxicity of vaccines demonstrated

Researchers have demonstrated a technique that has the potential to reduce the toxicity of vaccines and to make smaller doses more effective, according to a study published in PLoS Pathogens.

30 Dec 2005

New gene therapy maybe useful for treating muscular dystrophy

A new gene therapy technique that has shown promise in skin disease and hemophilia might one day be useful for treating muscular dystrophy, according to a new study by researchers at Stanford University School of Medicine.

29 Dec 2005

World's deadliest malaria parasite cloaking gene revealed

The world's deadliest malaria parasite, Plasmodium falciparum, sneaks past the human immune system with the help of a wardrobe of invisibility cloaks. If a person's immune cells learn to recognize one of the parasite's many camouflage proteins, the surviving invaders can swap disguises and slip away again to cause more damage. Malaria kills an estimated 2.7 million people annually worldwide, 75 percent of them children in Africa.

29 Dec 2005

Gene discovery may reinvigorate the body's immune system after fighting viral infections

Like boxers wearied by a 15-round bout, the immune system's CD8 T cells eventually become "exhausted" in their battle against persistent viral infection, and less effective in fighting the disease.

29 Dec 2005

Women suffering lupus OK to take oral contraceptives

Major study of women with either inactive or stable systemic lupus erythematosus (lupus) – a disease in which the body's immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs – were able to take oral contraceptives without increased risk of flares, or periods of increased disease activity, that characterize the disease.

22 Dec 2005

Scientists discover how HIV infects healthy cells

Using sophisticated detection methods, researchers at the Saint Louis University Institute for Molecular Virology (IMV) have demonstrated the molecular mechanism by which the HIV virus infects, or integrates, healthy cells. The discovery could lead to new drug treatments for HIV.

22 Dec 2005

Children could be saved from neuroblastoma using antibody therapy

Combination of T cell, antibody to neuroblastoma cells and molecule that spurs T cell growth is designed to treat low initial tumor levels or small cancer cell populations that survive initial treatment, according to St. Jude.

22 Dec 2005

Extremely infectious pneumonia-like disease slips through body's immune system

A new study found that an extremely infectious pneumonia-like disease in humans slips through the immune system's usual defense mechanisms.

21 Dec 2005

Synthetic compound could arrest development of Alzheimer's

Spanish chemists have developed a promising set of synthetic compounds that one day could help slow or perhaps halt the progression of Alzheimer's disease and other neurological disorders.

21 Dec 2005

Sanofi's human bird flu vaccine tests looking good

French drug company Sanofi Pasteur says early stage trials of an experimental vaccine against H5N1 bird flu have shown it provides a good immune response in humans and is safe.

19 Dec 2005

Lupus patients safe to go back on the pill

Two new studies confirm that women who suffer from lupus, a chronic disease that can lead to inflamed kidneys, can safely take oral contraceptives without fear that the pill will worsen their condition.

19 Dec 2005

Good results with cervical cancer vaccine in young girls

Drug company GlaxoSmithKline have had a good result with their new vaccine which was designed to prevent infection with the virus that causes cervical cancer.

19 Dec 2005

The role of genes in the development of non-Hodgkin's lymphomas

An international consortium of epidemilogists - including Dr. Alexandra Nieters and Professor Nikolaus Becker of the Clinical Epidemiology Division of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) - has conducted the first ever investigation of genetic factors in the development of non-Hodgkin’s lymphoma (NHL) in a study called InterLymph.

15 Dec 2005

65% of ovarian cancer cells sideline body's defences

Ovarian cancer tumour cells use two separate mechanisms to evade the body’s defensive reaction - and in so doing also elude a newly discovered counteraction from the surrounding tissue.

15 Dec 2005

New cell findings have implications for cancer, immune disorders

It all started 5 years ago when a University of Calgary neuroscientist sent blood from a patient with a neurological disorder to the laboratory of Dr. Marvin Fritzler, professor of medicine / biochemistry & molecular biology at the University of Calgary Faculty of Medicine.

15 Dec 2005

A colonization factor links Vibrio cholerae environmental survival and human infection

Opening a new door to an effective vaccine and therapy for a disease that strikes thousands annually, researchers at Dartmouth Medical School discovered that the bacteria that causes the intestinal disease Cholera spreads in the environment in much the same way it infects humans.

13 Dec 2005

Perimenopause critical for preventing heart disease and osteoporosis

Research in monkeys suggests that the perimenopause - the five to 10 years before a woman's menopause - is a critical time for preventing heart disease and osteoporosis.

13 Dec 2005