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Study demonstrates therapeutic potential of new class of synthetic oligonucleotides for DMD treatment

Research efforts associating scientists from the CNRS, UVSQ and INSERM within the Laboratoire END-ICAP, working in collaboration with a team from the University of Bern, has demonstrated the therapeutic potential of a new class of synthetic oligonucleotides in the treatment of Duchenne muscular dystrophy (DMD) using RNA "surgery".

4 Feb 2015

Merck announces US availability of BELSOMRA (suvorexant) for treatment of insomnia

Merck, known as MSD outside the United States and Canada, today announced that BELSOMRA (suvorexant) is now available at pharmacies in the United States for the treatment of insomnia in adults who have difficulty falling asleep and/or staying asleep.

4 Feb 2015

Two genetic mutations can interact to reduce risk for heart attack

Researchers have determined that two mutations on a single gene can interact in a way that lowers the carrier's risk for a heart attack.

4 Feb 2015

Exploring better treatment for adolescent idiopathic scoliosis

Adolescent idiopathic scoliosis (AIS) affects 2-3% of children aged between 10 and 16. It is more common in girls than in boys (with a ratio of 10-1). Besides the obvious physical signs derived from the visible spinal deformity, AIS can cause psychological and emotional problems (low self-esteem, poor self-image body, etc.) that significantly reduces patients' quality of life.

31 Jan 2015

Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

A public-private consortium led by the biotech Iproteos -based at Parc Científic de Barcelona (PCB)-, and comprised by the biopharmaceutical company Ascil-Biopharma, the Institute for Biomedical Research (IRB Barcelona), the Centre for Genomic Regulation (CRG) and the University of the Basque Country (UPV/EHU) has launched a project to advance the development of a new neuroprotective drug for the treatment of the cognitive impairment associated with schizophrenia and other mental disorders.

31 Jan 2015

Researchers identify molecular mechanisms that can prevent blindness, promote recovery from stroke

Research led by Nicolas Bazan, MD, PhD, Boyd Professor, Ernest C. and Yvette C. Villere Chair of Retinal Degeneration Research, and Director of the Neuroscience Center of Excellence at LSU Health New Orleans, has discovered gene interactions that determine whether cells live or die in such conditions as age-related macular degeneration and ischemic stroke.

31 Jan 2015

AACN to present 2015 Circle of Excellence Awards to 25 nurses at NTI

The American Association of Critical-Care Nurses (AACN) will bestow the 2015 Circle of Excellence Award on 25 nurses nationwide at the National Teaching Institute & Critical Care Exposition (NTI), San Diego, May 18-21.

29 Jan 2015

Promising results for stem cell therapy in MS

Preliminary findings suggest that nonmyeloablative haematopoietic stem cell transplantation may arrest, or even reverse, the progress of disease among patients with relapsing–remitting multiple sclerosis.

28 Jan 2015

Alectinib active against leptomeningeal metastases in ALK-positive NSCLC

Patients with anaplastic lymphoma kinase-rearranged non-small-cell lung cancer who have leptomeningeal metastases may benefit from treatment with the second-generation ALK inhibitor alectinib, a case series suggests.

28 Jan 2015

SRS fails to improve survival for NSCLC brain metastases patients

Phase III trial findings suggest that carrying out stereotactic radiosurgery before chemotherapy does not improve overall survival for non-small-cell lung cancer patients with asymptomatic brain metastases compared with chemotherapy alone.

28 Jan 2015

Novel technique could help identify cancerous tissue during brain tumor surgery

A novel radioguided surgery technique could quickly and effectively identify residual cancer cells during brain tumor surgery, with low radiation exposure for both patients and surgeons. The study, featured in the January 2015 issue of the Journal of Nuclear Medicine, reports that Y-90 DOTATOC, a beta-minus-emitting tracer, can effectively delineate the margins of meningiomas and high-grade gliomas.

28 Jan 2015

Study shows how gut bacteria can affect normal brain activity

The hundred trillion bacteria living in an adult human--mostly in the intestines, making up the gut microbiome--have a significant impact on behavior and brain health. The many ways gut bacteria can impact normal brain activity and development, affect sleep and stress responses, play a role in a variety of diseases, and be modified through diet for therapeutic use are described in a comprehensive Review article in Journal of Medicinal Food, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

23 Jan 2015

New discovery may help doctors develop better treatments for brain, spinal cord injuries

In a discovery that could dramatically affect the treatment of brain and spinal cord injuries, researchers have identified a previously unknown, beneficial immune response that occurs after injury to the central nervous system.

23 Jan 2015

Scientists identify gene that helps regulate development of central nervous system

Scientists have identified a gene that helps regulate how well nerves of the central nervous system are insulated, researchers at Washington University School of Medicine in St. Louis report.

23 Jan 2015

Study: Stem cell transplantation improves quality of life in patients with relapsing-remitting MS

Results from a preliminary study indicate that among patients with relapsing-remitting multiple sclerosis (MS), treatment with nonmyeloablative hematopoietic stem cell transplantation (low intensity stem cell transplantation) was associated with improvement in measures of disability and quality of life, according to a study in the January 20 issue of JAMA.

21 Jan 2015

Almost 42% of US drinkers use alcohol-interactive prescription medications, study finds

Approximately 71 percent of American adults drink alcohol. While alcohol interacts negatively with a number of commonly prescribed medications, little is known on a population level about the use of alcohol-interactive (AI) prescription medication among US drinkers. A new study has found that almost 42 percent of drinkers in the US population have used one or more alcohol-interactive prescription medications.

17 Jan 2015

Major investment boosts Scotland's gene research

A major investment in gene sequencing technology will secure Scotland's place as a world leader in a genomics revolution that is set to transform healthcare.

14 Jan 2015

Researchers identify new target that could lead to potential therapies for GBM

Researchers from Virginia Commonwealth University Massey Cancer Center and the VCU Institute for Molecular Medicine have identified a new protein-protein interaction that could serve as a target for future therapies for the most common form of brain cancer, glioblastoma multiforme (GBM).

14 Jan 2015

Review shows that fish compound can help combat cardiovascular disease

A major international review of a peptide originally found in fish that could be used in the battle against cardiovascular disease has been published.

13 Jan 2015

Newron, Zambon announce re-submission of safinamide NDA to FDA

Newron Pharmaceuticals S.p.A., a research and development company focused on novel CNS and pain therapies, and its commercial and development partner Zambon S.p.A., an international pharmaceutical company, announced today that the NDA for safinamide has been re-submitted to the US FDA.

29 Dec 2014

Central Nervous System News and Research

Study demonstrates therapeutic potential of new class of synthetic oligonucleotides for DMD treatment

Merck announces US availability of BELSOMRA (suvorexant) for treatment of insomnia

Two genetic mutations can interact to reduce risk for heart attack

Exploring better treatment for adolescent idiopathic scoliosis

Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

Researchers identify molecular mechanisms that can prevent blindness, promote recovery from stroke

AACN to present 2015 Circle of Excellence Awards to 25 nurses at NTI

Promising results for stem cell therapy in MS

Alectinib active against leptomeningeal metastases in ALK-positive NSCLC

SRS fails to improve survival for NSCLC brain metastases patients

Novel technique could help identify cancerous tissue during brain tumor surgery

Study shows how gut bacteria can affect normal brain activity

New discovery may help doctors develop better treatments for brain, spinal cord injuries

Scientists identify gene that helps regulate development of central nervous system

Study: Stem cell transplantation improves quality of life in patients with relapsing-remitting MS

Almost 42% of US drinkers use alcohol-interactive prescription medications, study finds

Major investment boosts Scotland's gene research

Researchers identify new target that could lead to potential therapies for GBM

Review shows that fish compound can help combat cardiovascular disease

Newron, Zambon announce re-submission of safinamide NDA to FDA

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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