Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

AstraZeneca introduces world’s most advanced drug discovery robot

AstraZeneca entered a new era in drug development today by unveiling NiCoLA-B, the world’s most advanced drug discovery robot, capable of performing experiments at an industrial scale in the search for new, life-saving medicines.

8 Dec 2016

Synthetic sgRNA for CRISPR genome editing

Chemically synthesized single guide RNA is the best way to do CRISPR genome editing. It is more pure than biological methods of creating guide RNAs, like in vitro transcription or plasmids. As a result, sgRNA leads to more consistency and higher quality.

8 Dec 2016

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine.

7 Dec 2016

Researchers identify critical paralog groups with indispensable role in cellular signalling pathways

Throughout evolutionary history, there have been genetic elements that have duplicated - giving rise to genes with different functions.

7 Dec 2016

Study reveals new way to improve stability of common protein drugs

Gaining access to important biopharmaceuticals needed to treat illnesses and autoimmune diseases is one of the biggest obstacles developing countries face.

2 Dec 2016

Monell Center receives Gates Foundation grant to support innovative global health research project

The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays."

1 Dec 2016

IUPUI scientists develop new synthetic method to shorten drug discovery and development process

Synthesizing useful new compounds is what pharmaceutical discovery and development is all about. Researchers at the School of Science at Indiana University-Purdue University Indianapolis have devised a method to substantially speed up the process.

1 Dec 2016

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity.

30 Nov 2016

New appointment to accelerate discovery of patient-centred medicines

The new Medicines Discovery Catapult (MDC) is pleased to announce the appointment of Ed Owen to put medical research charities and patient groups at the heart of the development of new therapies in the UK.

29 Nov 2016

Dilon and GE receive FDA approval for Discovery NM750b breast imaging system

DILON Diagnostics and GE Healthcare are pleased to announce the FDA clearance of the Molecular Breast Imaging (MBI) localization accessory for breast biopsy.

26 Nov 2016

De-risking drug development free webinar from Envigo

De-risking represents a relatively new but developing strategy designed to quickly assess if a new drug has a liability. Knowing your compound’s risk for drug-to-drug interactions (DDI), drug induced liver injury (DILI) and metabolites in safety testing (MIST) early on in drug development, leads to greater confidence and added value on your molecule’s journey to market.

18 Nov 2016

DILON Diagnostics to distribute GE's Discovery NM750b breast imaging system in North America

DILON Diagnostics and GE Healthcare are pleased to announce that they have signed an agreement for DILON to be the exclusive distributor of GE's Discovery NM750b Molecular Breast Imaging system in North America.

16 Nov 2016

Research shows CRAC channel inhibitors decrease lesion size, brain hemorrhage, and neurological deficits in TBI model

Researchers from the San Francisco Veterans Affairs Medical Center and UCSF, and CalciMedica, Inc., are presenting a poster at the 46th annual Society for Neuroscience meeting in San Diego describing the use of calcium release-activated calcium (CRAC) channel inhibitors in traumatic brain injury (TBI).

16 Nov 2016

Researcher investigating drugs to prevent lung cancer from spreading

The American Cancer Society has reported that lung cancer, which kills more Americans than any other type of cancer, is expected result in an estimated 158,080 deaths in 2016.

11 Nov 2016

New discovery may lead to better treatment options for pancreatic cancer patients

Pancreatic cancer, the third leading cause of cancer-related deaths, is projected to be the second by the year 2030, according to a study in the journal of Cancer Research.

11 Nov 2016

Compugen program shows potential for development of new immunotherapy treatments for solid tumors

Compugen Ltd., a leading predictive drug discovery company, today presented new data for its preclinical CGEN-15029 program demonstrating the potential for the development of new cancer immunotherapy treatments for solid tumors, including the potential for drug combination with current immune checkpoint blockers.

11 Nov 2016

C-SOPS, Thermo Fisher Scientific to accelerate research on continuous manufacturing techniques for drug discovery

The Engineering Research Center for Structured Organic Particulate Systems, based at the Rutgers School of Engineering, and Thermo Fisher Scientific have collaborated to accelerate the university's ongoing research on continuous manufacturing techniques for pharmaceutical discovery.c

11 Nov 2016

Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Scientists at the University of Sussex, trying to uncover how the common Epstein-Barr virus causes blood cancer in adults and children, have discovered how the virus takes control of two genes involved in cancer development so it can switch them on or off.

10 Nov 2016

NCATS funds collaboration initiative aimed at repurposing antimalarial to combat Ebola virus

The National Center for Advancing Translational Sciences recently awarded $596,533.00 to Collaborations Pharmaceuticals, Inc. to initiate a partnership with Texas Biomedical Research Institute aimed at repurposing an antimalarial for use against the Ebola virus.

10 Nov 2016

Researchers discover genetic alterations in autism gene that reduces brain activity

Scientists at McMaster University's Stem Cell and Cancer Research Institute in collaboration with Sick Children's Hospital have discovered genetic alterations in the gene DIXDC1 in individuals with autism spectrum disorders (ASD).

8 Nov 2016

Drug Discovery News and Research

Further Reading

AstraZeneca introduces world’s most advanced drug discovery robot

Synthetic sgRNA for CRISPR genome editing

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Researchers identify critical paralog groups with indispensable role in cellular signalling pathways

Study reveals new way to improve stability of common protein drugs

Monell Center receives Gates Foundation grant to support innovative global health research project

IUPUI scientists develop new synthetic method to shorten drug discovery and development process

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

New appointment to accelerate discovery of patient-centred medicines

Dilon and GE receive FDA approval for Discovery NM750b breast imaging system

De-risking drug development free webinar from Envigo

DILON Diagnostics to distribute GE's Discovery NM750b breast imaging system in North America

Research shows CRAC channel inhibitors decrease lesion size, brain hemorrhage, and neurological deficits in TBI model

Researcher investigating drugs to prevent lung cancer from spreading

New discovery may lead to better treatment options for pancreatic cancer patients

Compugen program shows potential for development of new immunotherapy treatments for solid tumors

C-SOPS, Thermo Fisher Scientific to accelerate research on continuous manufacturing techniques for drug discovery

Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

NCATS funds collaboration initiative aimed at repurposing antimalarial to combat Ebola virus

Researchers discover genetic alterations in autism gene that reduces brain activity

Genomics and Protein Expression eBook

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