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Research uncovers ASPL's critical role in stress granule life cycle

Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP is a protein essential for breaking up stress granules and has been linked to neurodegenerative diseases.

9 Oct 2025

Study warns of inevitable child mortality rise without unimpeded aid in Gaza

More than 54,600 children in Gaza are estimated to be acutely malnourished, including over 12,800 severely so, with few therapeutic options available to them. With measurements up to the middle of August 2025, the study comprehensively tracks wasting among children during the war, estimates population prevalence, and highlights unprecedented increases in child malnutrition following periods of blockades and severe aid restrictions.

9 Oct 2025

Many men receive frequent prostate cancer tests without symptoms

Current prostate specific antigen (PSA) testing "may not effectively target testing to those most likely to benefit, raising concerns about overtesting" warn researchers from the University of Oxford in a study of over 10 million men across England published by The BMJ today.

8 Oct 2025

Nasal spray of gold nanoparticles delivers lithium directly to the brain

In the form of a 'nasal spray', tiny gold particles act as carriers, delivering a treatment directly to the brain: developed by scientists at the Università Cattolica Rome campus/Fondazione Policlinico Universitario A. Gemelli IRCCS, a new nanotechnological device for the treatment and prevention of neuropsychiatric and neurodegenerative diseases.

8 Oct 2025

UCSF team uncovers breakthrough immunotherapy for colon cancer liver metastases

Advanced colon cancer is the leading cause of cancer-related death in young American men and the second highest worldwide. In the majority of these patients, as the cancer advances it metastasizes to the liver.

8 Oct 2025

Repeated sampling offers insight into glioblastoma therapy response

A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect when a cancer treatment is activating the immune system in recurrent glioblastoma (GBM), even when traditional imaging measures cannot.

8 Oct 2025

Brainstem damage found to be behind long-lasting effects of severe Covid-19

Damage to the brainstem - the brain's 'control center' - is behind long-lasting physical and psychiatric effects of severe Covid-19 infection, a study suggests.

8 Oct 2025

Inappropriate triage prolongs time to pain medication in vaso-occlusive crisis

Most individuals living with sickle cell disease who presented to the emergency department with a pain crisis, known as vaso-occlusive crisis (VOC), were not triaged appropriately according to established national guidelines, reveals a study published today in Blood Advances.

8 Oct 2025

Ireland launches next phase of national precision oncology program

Today (8th October), Ireland's Minister for Further and Higher Education, Research, Innovation and Science, James Lawless TD, launched Phase 2 of the country's leading and largest ever cancer research program, Precision Oncology Ireland (POI).

8 Oct 2025

Japan's registry transforms outcomes for infants with biliary atresia

Biliary atresia (BA) is the leading cause of liver failure in infants, marked by progressive destruction of the bile ducts. Until the late 1950s, the disease was universally fatal, with no effective treatments. The development of the Kasai portoenterostomy brought new hope, but outcomes varied widely, and many patients still required liver transplantation (LTx).

8 Oct 2025

Asthma and multiple allergies raise the risk of failed oral food challenges

Research shows asthma and multi-food allergies elevate the odds of reactions in oral food challenges, emphasizing the importance of careful patient selection.

8 Oct 2025

California’s nursing shortage is getting worse. Front-line workers blame management.

California, like much of the nation, is not producing enough nurses working at bedsides to meet the needs of an aging and diverse population, fueling a workforce crunch that risks endangering quality patient care.

8 Oct 2025

Depression during pregnancy raises risk of gestational diabetes

Findings indicate that antenatal depression increases the risk of gestational diabetes, underscoring the need for early intervention and lifestyle support.

8 Oct 2025

Whole genome sequencing may guide care for thousands of breast cancer patients

Whole genome sequencing offered to breast cancer patients is likely to identify unique genetic features that could either guide immediate treatment or help match patients to clinical trials for over 15,000 women a year, say scientists at the University of Cambridge.

7 Oct 2025