Immune Response News and Research

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Persistence of viral RNA following acute infection

Professor Diane Griffin from the Johns Hopkins Bloomberg School of Public Health, USA, has recently explained the persistence mechanism of viral RNA in the human body after clinical recovery from acute infection.

6 Jun 2022

The frequency and nature of RNA errors in both SARS-CoV-2 and its vaccine

A recent article demonstrated that SARS-CoV-2 mutants and vaccine variability stem from ribonucleic acid polymerase inaccuracy.

6 Jun 2022

Safety and efficacy of SCB-2019 COVID vaccine candidate as a ChAdOx1-S booster

In a recent study posted to the medRxiv* pre-print server, researchers evaluated the immunogenicity of booster doses of alum-adjuvanted SCB-2019 vaccine candidate's three formulations.

6 Jun 2022

Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals

A recent phase 1/2 study under review at the Nature Portfolio journal and posted to the Research Square* preprint server demonstrated that a peptide-centered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) T-cell activator, CoVac-1, was efficient in B-cell deficient people.

6 Jun 2022

Immune responses may exist on a finer spectrum than previously believed

Researchers from McGill University and the US National Cancer Institute (NCI) have made some surprising discoveries about our immune system.

3 Jun 2022

Vaccine effectiveness against SARS-CoV-2 reinfection during periods with different dominant SARS-CoV-2 variants

A new study found that despite a lower COVID-19 vaccine efficacy against reinfection with the Omicron variant, these vaccines demonstrate a marked efficacy against reinfection with SARS-CoV-2 Alpha and Delta variants, as well as the Omicron variant.

3 Jun 2022

Study offers clues about the shift of harmless environmental bacterium to a dreaded pathogen

Hospital-acquired infections (HAIs) are often particularly difficult to treat because the pathogens have developed resistance to common antibiotics.

3 Jun 2022

Brain motor and fear circuits orchestrate the immune response to acute stress

A new study explores how acute stressors affected mice in terms of their immune responses in specific regions of the brain.

2 Jun 2022

Immune modulator drugs improved clinical status, reduced deaths among patients hospitalized with COVID-19

A large randomized, placebo-controlled clinical trial led by the National Institutes of Health shows that treating adults hospitalized with COVID-19 with infliximab or abatacept - drugs widely used to treat certain autoimmune diseases - did not significantly shorten time to recovery but did substantially improve clinical status and reduce deaths.

2 Jun 2022

New "masked" version of immunotherapy could help fight cancer without causing side effects

Many cancer treatments are notoriously savage on the body; they attack healthy cells at the same time as tumor cells, causing a plethora of side effects.

1 Jun 2022

Inhibiting immune response-related enzyme holds promise in preventing or treating severe COVID-19

Blocking an immune response-related enzyme holds promise in preventing or treating severe COVID-19 symptoms by reducing inflammation, tissue injury and blood clots in the lungs, new research in mice suggests.

1 Jun 2022

Genetically modified herpes virus can be used in the fight against cancer

Viruses can make animals and humans sick - or healthy: Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have succeeded in genetically modifying the herpes simplex virus type 1, which triggers painful cold sores, in such a way that it can be used in the fight against cancer in the future.

1 Jun 2022

Gene therapy for degenerative retinal disease has no safety concerns but fails to improve vision loss

A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, with even the highest dose. LHON affects the optic nerve, which carries visual signals from the light-sensing retina to the brain.

1 Jun 2022

Immune Response News and Research

Persistence of viral RNA following acute infection

The frequency and nature of RNA errors in both SARS-CoV-2 and its vaccine

Safety and efficacy of SCB-2019 COVID vaccine candidate as a ChAdOx1-S booster

Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals

Immune responses may exist on a finer spectrum than previously believed

Vaccine effectiveness against SARS-CoV-2 reinfection during periods with different dominant SARS-CoV-2 variants

Study offers clues about the shift of harmless environmental bacterium to a dreaded pathogen

Brain motor and fear circuits orchestrate the immune response to acute stress

Immune modulator drugs improved clinical status, reduced deaths among patients hospitalized with COVID-19

New "masked" version of immunotherapy could help fight cancer without causing side effects

Inhibiting immune response-related enzyme holds promise in preventing or treating severe COVID-19

Genetically modified herpes virus can be used in the fight against cancer

Gene therapy for degenerative retinal disease has no safety concerns but fails to improve vision loss

Exposure to traffic-related air pollutants linked with pregnancy complications

Study analyzes how four types of COVID-19 vaccines prepare the body to fight SARS-CoV-2

Can COVID-19 pass from mothers to newborns?

New compounds for cancer immunotherapy via STING-mediated immune activation

Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Study shows how stress has a major impact on the immune system's ability to fight infections

Investigating incidence and clinical features of post-acute sequelae of COVID-19 in children and adolescents

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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