Immune System News and Research

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Promising new tuberculosis drug enters clinical trial

A promising new drug candidate that may be effective against both actively dividing and slow-growing Mycobacterium tuberculosis (M. tb) has begun testing in humans, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, announced this week.

15 Jun 2005

Nanotechnology used to smuggle a powerful chemotherapeutic drug inside tumor cells

University of Michigan scientists have created the nanotechnology equivalent of a Trojan horse to smuggle a powerful chemotherapeutic drug inside tumor cells - increasing the drug's cancer-killing activity and reducing its toxic side effects.

15 Jun 2005

Drinking during pregnancy can increase the risk of infection in newborns

Despite public-information campaigns and physician advice about alcohol consumption during pregnancy, between 15 and 25 percent of pregnant women continue to drink each month, and five to 10 out of 1,000 pregnant women drink an average of seven or more drinks per week.

14 Jun 2005

US scientists find "mother of all brain stem cells"

Scientists at the University of Florida have been able grow brain cells in the laboratory.

14 Jun 2005

Chemokine Therapeutics granted new U.S patent

Chemokine Therapeutics has announced that it has been granted U.S. Patent No. 6,875,738 relating to the use of its anti-cancer compound, CTCE-9908, in the treatment of cancer and inhibition of angiogenesis. CTCE-9908 is designed to block CXCR4, a receptor found on the surface of cancer cells.

14 Jun 2005

Chemotherapy for brain tumors is boosted after vaccine targets resistance-related TRP-2 antigen

In the August issue of the journal Oncogene, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute describe a molecular mechanism that appears to make malignant brain tumors more vulnerable to chemotherapy after they have been treated with the dendritic cell vaccine.

13 Jun 2005

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer, thanks to a newly developed technique that enables scientists to mass-produce human papillomavirus (HPV) in the laboratory.

13 Jun 2005

Research accelerates the search for an effective cancer vaccine

By devising a novel way to package the genome of a common human tumor virus - the virus that causes common warts, genital warts and that is implicated in prevalent cancers - scientists have paved the way for making the pathogen far more accessible to biomedical science.

13 Jun 2005

Psychosocial factors and interleukin-6 among women with advanced ovarian cancer

A new study funded by the National Cancer Institute reports that social support and other behavioral factors are related to levels of a circulating protein, which at high levels is associated with a poor prognosis in advanced ovarian cancer.

13 Jun 2005

Half of 580 women diagnosed with breast cancer in one study experienced lymphedema

The good news is that there are nearly two million breast cancer survivors in the United States , and survival rates continue to increase for patients with this disease. But the flip side is that survival can present its own set of little-known complications.

12 Jun 2005

Dendritic cell vaccination can dramatically speed up the immunization process

Parents often wonder why it takes a year or more and multiple shots to fully immunize their children against diseases like diphtheria and pertussis.

12 Jun 2005

If a dividing cell's activity is a pop song, then the same process in an immune cell is an extended-play dance remix

The basics of cell division are the same in both, but there's a heck of a lot more going on in immune cells, Johns Hopkins scientists have discovered.

10 Jun 2005

Optimists don't always fare better than pessimists in their immunologic response to stress

The difference seems to be based on the degree of stress facing the optimist and the degree to which a pessimist avoids the problem, according to an article in the current issue of the journal Brain, Behavior, and Immunity by Suzanne Segerstrom, Ph.D., of the University of Kentucky.

10 Jun 2005

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

Thomas C. Quinn, M.D., a Johns Hopkins physician and scientist, who has spent the best part of the last 25 years leading major efforts to combat HIV and AIDS throughout the world, is calling for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic.

10 Jun 2005

Exercise helps recovery after chemotherapy for breast cancer

Exercise after chemotherapy for breast cancer boosted the activity of infection-fighting T cells in women who worked out regularly, according to data from a study conducted at Penn State University under the direction of Andrea Mastro, professor of microbiology and cell biology.

10 Jun 2005

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Researchers at Johns Hopkins have uncovered how a majority of the genetic changes in the hepatic-C virus, the most common cause of liver disease, allow it to evade the body's immune system during infection.

10 Jun 2005

Urgent call for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic

In an article appearing in the journal Science online June 10, Thomas C. Quinn, M.D., professor of infectious diseases at Hopkins and a senior investigator at the National Institute of Allergy and Infectious Disease, reports that women have in the last 20 years moved from those least affected by HIV to those in whom the disease is spreading fastest.

10 Jun 2005

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer’s disease have an immune defect making it difficult to clean away these wastes.

From MP Biomedicals, LLC 10 Jun 2005

Multiple sclerosis drug Tysabri could be back on the market later in the year

The drug Tysabri which was approved by the Food and Drug Administration (FDA) for the treatment of multiple sclerosis in November 2004, was taken off the market in late February, after two cases of progressive multifocal leukoencephalopathy, or PML, appeared in patients given the drug during clinical trials.

9 Jun 2005

Promising new vaccine candidate to prevent middle ear infections

Hoping to prevent ear infections for the more than 15 million children in the United States who suffer from them, a promising new vaccine candidate to prevent middle ear infections (otitis media) is being developed by researchers at the Columbus Children’s Research Institute (CCRI) on the campus of Columbus Children’s Hospital.

9 Jun 2005

Immune System News and Research

Promising new tuberculosis drug enters clinical trial

Nanotechnology used to smuggle a powerful chemotherapeutic drug inside tumor cells

Drinking during pregnancy can increase the risk of infection in newborns

US scientists find "mother of all brain stem cells"

Chemokine Therapeutics granted new U.S patent

Chemotherapy for brain tumors is boosted after vaccine targets resistance-related TRP-2 antigen

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer

Research accelerates the search for an effective cancer vaccine

Psychosocial factors and interleukin-6 among women with advanced ovarian cancer

Half of 580 women diagnosed with breast cancer in one study experienced lymphedema

Dendritic cell vaccination can dramatically speed up the immunization process

If a dividing cell's activity is a pop song, then the same process in an immune cell is an extended-play dance remix

Optimists don't always fare better than pessimists in their immunologic response to stress

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

Exercise helps recovery after chemotherapy for breast cancer

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Urgent call for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

Multiple sclerosis drug Tysabri could be back on the market later in the year

Promising new vaccine candidate to prevent middle ear infections

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