Immune System News and Research

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Carbohydrate-based vaccine against cancer?

Couldn't we be immunized against cancer? This sounds like a dream, but is in fact a thoroughly realistic research goal. American researchers have now taken an important step forward in the development of a cancer vaccine.

29 Aug 2005

Previously unknown family of plague virulence factors identified

Researchers at Duke University Medical Center have identified a previously unknown family of virulence factors that make the bacterium responsible for the plague especially efficient at killing its host.

28 Aug 2005

Ways to avoid hazards of heart bypass under study

The heart-lung bypass machine that stills the heart while surgeons bypass an adult’s clogged arteries or repair a baby’s malformed heart can also trigger a potentially deadly inflammatory response.

28 Aug 2005

Immunity - another important function of the mitochondria

Researchers have discovered a surprise lurking inside mitochondria, the power plants that are present in every cell. It turns out that these powerhouses also contain a protein that triggers the immune system to attack viral invaders.

28 Aug 2005

Inflammation plays an important role in post-operative stroke

Duke University Medical Center researchers have discovered that patients who have two specific gene variants are more than three times as likely to suffer a stroke after heart surgery.

26 Aug 2005

New strategy to turn off the function of a special group of T cells to suppress immune response to tumors

A special stretch of genetic material may turn off the immune suppression that stymies attempts to fight cancer with a vaccine, said researchers at Baylor College of Medicine (BCM) at Houston.

26 Aug 2005

The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of Helicobacter-induced MALT lymphoma

Research led by Dr. Anne Mueller at Stanford University School of Medicine demonstrates that successful eradication of Helicobacter may not prevent future aggressive gastric lymphoma since resting B cells are left behind.

25 Aug 2005

Experimental immunusuppressant drug preserves transplanted kidneys

An international team of transplant physicians has shown that the investigational drug belatacept (LEA29Y) preserves transplanted kidney function as effectively as cyclosporine, the drug most commonly used to prevent the immune system from rejecting transplanted organs.

24 Aug 2005

Brain plays an important role in the maintenance of proper bone density

The results of this research, involving a study of the activity of the protein interleukin 1 in the brain, comprise not only a breakthrough in understanding the regulation of bone density by the brain but also hold promise for the development of future treatment for osteoporosis, say the researchers.

24 Aug 2005

New drug that selectively blocks immune responses protects kidneys after transplant

In an international clinical trial, a new drug that selectively blocks immune responses has proved as effective in preventing acute kidney transplant rejection as cyclosporine, the standard anti-rejection treatment.

24 Aug 2005

Hundreds of identified genes involved in the pathophysiology of ulcerative colitis and Crohn disease

In a paper published in PLoS Medicine researchers from the German Genome Research Network have analysed the expression of thousands of genes from patients with inflammatory bowel disease (ulcerative colitis and Crohn disease) using a genome wide approach to produce a comprehensive picture of which genes are activated in these conditions.

24 Aug 2005

First study to test the role of RNA chemical modifications on immunity

The investigators published their findings in the August issue of Immunity. "We think this study will open a new area of research in understanding how our immune systems protect us," says Weissman.

23 Aug 2005

Birth order not a factor in multiple sclerosis risk

A new Canadian study suggests that the youngest children in a family are not less likely than older siblings to develop multiple sclerosis (MS).

22 Aug 2005

Gene therapy advance shows potential for developing improved treatment for hemophilia

A virus that typically infects insects could help with the development of gene therapy treatment for Hemophilia A, a condition in which even a bump on the knee can cause serious internal bleeding in people.

22 Aug 2005

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

A protein previously thought to merely hinder the activity of a key cellular protein linked to cancer cell death, now appears to mimic the cellular signaling of that protein; potentially leading to the development of lymphoma.

22 Aug 2005

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Researchers at The University of Texas M. D. Anderson Cancer Center and the National Cancer Institute have found that an experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma, even though prior therapy had eliminated virtually all of the B cells thought necessary to mount such a defense.

22 Aug 2005

Non-invasive imaging may help predict type 1 diabetes and response to treatment in humans

A key obstacle to early detection of type 1 diabetes - as well as to rapid assessment of the effectiveness of therapeutic intervention - has been the lack of direct, non-invasive technologies to visualize inflammation in the pancreas, an early manifestation of disease.

22 Aug 2005

New phenomenon in which one bacterial cell can stop the growth of another on physical contact

Scientists have discovered a new phenomenon in which one bacterial cell can stop the growth of another on physical contact. The bacteria that stop growing may go into a dormant state, rather than dying. The findings have implications for management of chronic diseases, such as urinary tract infections.

22 Aug 2005

New hope for those deaf from immune system attack

A new study may one day help those deafened by immune system attack, and possibly also lead to a test that could show which patients may be helped by immediate steroid treatment.

16 Aug 2005

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

For people with long-standing rheumatoid arthritis, combined treatment with the new "biologic" drug adalimumab and methotrexate is about five times more effective than methotrexate alone, according to a new systematic review of studies.

15 Aug 2005

Immune System News and Research

Carbohydrate-based vaccine against cancer?

Previously unknown family of plague virulence factors identified

Ways to avoid hazards of heart bypass under study

Immunity - another important function of the mitochondria

Inflammation plays an important role in post-operative stroke

New strategy to turn off the function of a special group of T cells to suppress immune response to tumors

The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of Helicobacter-induced MALT lymphoma

Experimental immunusuppressant drug preserves transplanted kidneys

Brain plays an important role in the maintenance of proper bone density

New drug that selectively blocks immune responses protects kidneys after transplant

Hundreds of identified genes involved in the pathophysiology of ulcerative colitis and Crohn disease

First study to test the role of RNA chemical modifications on immunity

Birth order not a factor in multiple sclerosis risk

Gene therapy advance shows potential for developing improved treatment for hemophilia

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Non-invasive imaging may help predict type 1 diabetes and response to treatment in humans

New phenomenon in which one bacterial cell can stop the growth of another on physical contact

New hope for those deaf from immune system attack

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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