Cell Death News and Research

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Cell powerhouses may be good therapeutic target for brain injury

Cell powerhouses are typically long and lean, but with brain injury such as stroke or trauma, they can quickly become bloated and dysfunctional, say scientists who documented the phenomena in real time for the first time in a living brain.

10 Jan 2017

Experimental treatment approach reverses cognitive decline and neuropathology in AD mouse model

Treatment with an inhibitor of 12/15-lipoxygenase, an enzyme elevated in patients with Alzheimer's disease (AD), reverses cognitive decline and neuropathology in an AD mouse model, reports a new study in Biological Psychiatry.

5 Jan 2017

New research suggests novel combination approach to fight against gliomas

"Devastating" and "dismal." That's how leading researchers describe the present outlook for malignant brain tumors. The median survival rate for patients with glioblastoma multiforme, or GBM, is a mere 14.2 months.

4 Jan 2017

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

Richard Myers, PhD, professor of neurology at Boston University School of Medicine, was recently awarded $100,000 from the Ellison Foundation for research to further study a Parkinson's disease (PD) target.

4 Jan 2017

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study.

3 Jan 2017

Study shows new role of zinc in optic nerve injury

For more than two decades, researchers have tried to regenerate the injured optic nerve using different growth factors and/or agents that overcome natural growth inhibition.

3 Jan 2017

Whitehead Institute researchers identify mechanism underlying cancer drug-resistance

The use of proteasome inhibitors to treat cancer has been greatly limited by the ability of cancer cells to develop resistance to these drugs.

27 Dec 2016

New findings about key cellular protein could lead to treatments for neurodegenerative diseases

New details learned about a key cellular protein could lead to treatments for neurodegenerative diseases, such as Parkinson's, Huntington's, Alzheimer's, and amyotrophic lateral sclerosis (ALS).

27 Dec 2016

Scientists find explanation for vulnerability of children to collateral damage from cancer treatment

Despite many successes in treating pediatric cancer, young children remain at high risk for developing severe, long-lasting impairments in their brain, heart, and other vital organs from chemotherapy and radiation treatments. In adults, however, these tissues are relatively spared.

22 Dec 2016

New study reveals IRBIT's role in facilitating apoptosis

Billions of cells in our bodies die every day in an important process called apoptosis. Now, researchers at the RIKEN Brain Science Institute have mapped out a sequence of events that are necessary for apoptosis to occur properly.

21 Dec 2016

Genetic mutation may increase susceptibility to cytomegalovirus infection

Experimenting with human cells and mice, Johns Hopkins researchers have found that a genetic mutation that alters a protein called NOD1 may increase susceptibility to human cytomegalovirus (CMV) infection.

20 Dec 2016

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Based on the study of cell signalling networks, the cell signals that drugs alter when they reach their target molecule, an exhaustive in silico analysis of the pairing of 64 therapeutic agents used to treat breast cancer (half already in use and the other half in clinical testing phase) has allowed researchers at the Institute for Research in Biomedicine to identify 10 new and previously untested combinations that hold potential for the treatment of breast cancer.

20 Dec 2016

FDA awards accelerated approval to new ovarian cancer drug

The U.S. Food and Drug Administration today granted accelerated approval to Rubraca (rucaparib) to treat women with a certain type of ovarian cancer.

19 Dec 2016

Lab-based cellular tests reveal that e-cigarette vapour does not induce DNA damage

E-cigarette vapour does not damage DNA, even at doses 28 times that of equivalent smoke exposure.

16 Dec 2016

Lactate component responsible for anti-tumor effects of plasma medicine, research shows

Physical plasma is one of the four fundamental states of matter, together with solid, liquid, and gas, and can be completely or partially ionized (thermal/hot or non-thermal/cold plasma, respectively).

15 Dec 2016

Scientists explain concept of combining NO gas therapy with starvation of tumor cells for nanomedical treatment

Biocompatible nanocapsules, loaded with an amino acid and equipped with an enzyme now combine two anti-tumor strategies into a synergistic treatment concept. Researchers hope this increases effectiveness and decreases side effects.

14 Dec 2016

Novel plasma medicine with anti-tumor effect discovered

Nagoya University researchers develop cold plasma-activated Ringer's solution for chemotherapy. The solution has anti-tumor effects in vitro and in vivo that derive from the lactate component.

14 Dec 2016

UNIST study could open up new avenues of research in cancer treatment

The new study, by researchers from UNIST demonstrates a more holistic light-based treatment to nuke cancer cells instead of surgery. The results, reported in the September issue of the Journal of the American Chemical Society, could open up new avenues of research in cancer treatment.

14 Dec 2016

Jets of plasma used in arc welding may help kill cancer cells and heal wounds

JETS of plasma traditionally used in arc welding could soon be used to kill cancer cells and heal wounds.

9 Dec 2016

Cell Death News and Research

Cell powerhouses may be good therapeutic target for brain injury

Experimental treatment approach reverses cognitive decline and neuropathology in AD mouse model

New research suggests novel combination approach to fight against gliomas

How does the brain control appetite?

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

Study shows new role of zinc in optic nerve injury

Whitehead Institute researchers identify mechanism underlying cancer drug-resistance

New findings about key cellular protein could lead to treatments for neurodegenerative diseases

Scientists find explanation for vulnerability of children to collateral damage from cancer treatment

New study reveals IRBIT's role in facilitating apoptosis

Genetic mutation may increase susceptibility to cytomegalovirus infection

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

FDA awards accelerated approval to new ovarian cancer drug

Lab-based cellular tests reveal that e-cigarette vapour does not induce DNA damage

Lactate component responsible for anti-tumor effects of plasma medicine, research shows

Scientists explain concept of combining NO gas therapy with starvation of tumor cells for nanomedical treatment

Novel plasma medicine with anti-tumor effect discovered

UNIST study could open up new avenues of research in cancer treatment

Jets of plasma used in arc welding may help kill cancer cells and heal wounds

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics