Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Research findings suggest new treatment for breast, colon, melanoma and other cancers

A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results.

3 May 2013

Better individual risk prediction for women with breast cancer is getting nearer, says study author

A test that measures the expression levels of 58 genes in oestrogen receptor-positive breast cancers can effectively differentiate between patients who are at higher and lower risk for having their cancer recur elsewhere in the body more than five years after diagnosis, researchers report.

3 May 2013

Prosigna Breast Cancer Prognostic Gene Signature Assay predicts ROR in women with early-stage breast cancer

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and molecular diagnostic products, today announced results from two studies that are featured in oral presentations this week at IMPAKT Breast Cancer Conference.

2 May 2013

Researchers find that VEGF may not have any prognostic value for advanced prostate cancer

The well-studied protein VEGF does not appear to have any prognostic or predictive value for men with locally advanced prostate cancer, researchers from the Department of Radiation Oncology at Thomas Jefferson University Hospital and other institutions found in a retrospective study published online April 25 in the journal BMC Radiation Oncology.

30 Apr 2013

New risk classification system proposed for prostate cancer

US researchers have put forward a risk stratification system for patients with intermediate-risk prostate cancer undergoing dose-escalated external-beam radiation therapy.

29 Apr 2013

Student researchers get new view of the dynamics of cancer cells as they metastasize

A team of student researchers and their professors from 20 laboratories around the country have gotten a new view of cancer cells. The work could shed light on the transforming physical properties of these cells as they metastasize, said Jack R. Staunton, a Ph.D. candidate at Arizona State University in the lab of Prof. Robert Ros, and the lead author of a paper reporting on the topic.

29 Apr 2013

Researchers discover new insights into how cells make transition from nonmalignant to metastatic

Cancer cells that can break out of a tumor and invade other organs are more aggressive and nimble than nonmalignant cells, according to a new multi-institutional nationwide study.

29 Apr 2013

Study confirms that mesenchymal stem cells may help treat cancer

Injection of human stem cells into mice with tumors slowed down tumor growth, finds research published in BioMed Central's open access journal Stem Cell Research & Therapy.

29 Apr 2013

Biological imaging technologies create a new way to learn about cells

Researchers have married two biological imaging technologies, creating a new way to learn how good cells go bad. "Let's say you have a large population of cells," said Corey Neu, an assistant professor in Purdue University's Weldon School of Biomedical Engineering.

26 Apr 2013

Surgery extends life for metastatic colorectal cancer patients

Individuals with colorectal cancer that has metastasized to the liver or lung live longer after curative surgery plus chemotherapy than their counterparts who receive palliative chemotherapy alone, report researchers.

25 Apr 2013

Epstein–Barr virus linked to improved gastric cancer survival

Research shows that Epstein–Barr virus positivity in gastric tumor cells is associated with improved prognosis.

25 Apr 2013

Mechanism of tumor suppressor p53 inactivation described

Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don’t belong. One protein that keeps healthy cells from behaving this way is a tumor suppressor named p53. This protein stops potentially precancerous cells from dividing and induces suicide in those that are damaged beyond repair. Not surprisingly, p53’s critical function is disrupted in most cancers.

25 Apr 2013

New risk classification system proposed for prostate cancer

US researchers have put forward a risk stratification system for patients with intermediate-risk prostate cancer undergoing dose-escalated external-beam radiation therapy.

25 Apr 2013

Novel approach using Listeria bacteria shows promise against metastatic pancreatic cancer

Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a therapy for pancreatic cancer that uses Listeria bacteria to selectively infect tumor cells and deliver radioisotopes into them.

25 Apr 2013

XBiotech announces enrollment of first patient in Xilonix Phase III trial for treatment of cachexia

XBiotech announced today enrollment of the first patient into its Phase III trial of Xilonix. The Pivotal study is designed to improve health and survival of late stage colorectal cancer patients with associated cachexia.

25 Apr 2013

CNIO researcher-led consortium to receive MRA grant to advance research in melanoma

A consortium led by the Spanish National Cancer Research Centre's researcher Mar-a S. Soengas −Programme Director of the Centre-s Molecular Pathology Programme and Leader of the CNIO Melanoma Group− has been selected to receive funding from the Melanoma Research Alliance, the most important private international melanoma research foundation, in order to advance research in melanoma; this type of skin tumour represents one of oncology's biggest challenges due to its high incidence and malignancy.

24 Apr 2013

Research shows sophisticated genetic circuits allow individual bacterium to act on its own

Individual freedom and social responsibility may sound like humanistic concepts, but an investigation of the genetic circuitry of bacteria suggests that even the simplest creatures can make difficult choices that strike a balance between selflessness and selfishness.

23 Apr 2013

Individual cancer cells in blood stream are responsible for metastases in breast cancer patients

Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the main cause of cancer-related deaths.

23 Apr 2013

Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggests that an unusual experimental drug can reduce breast-cancer aggressiveness, reverse resistance to the drug fulvestrant and perhaps improve the effectiveness of other breast-cancer drugs.

23 Apr 2013

Study provides medical chemists with tools to design safer drugs, predict their side effects

Yellow vision, pseudo-pulmonary obstruction, involuntary body movements, respiratory paralysis. These are some of the 1,600 known side effects (SEs) produced by drugs.

22 Apr 2013

Metastasis News and Research

Further Reading

Research findings suggest new treatment for breast, colon, melanoma and other cancers

Better individual risk prediction for women with breast cancer is getting nearer, says study author

Prosigna Breast Cancer Prognostic Gene Signature Assay predicts ROR in women with early-stage breast cancer

Researchers find that VEGF may not have any prognostic value for advanced prostate cancer

New risk classification system proposed for prostate cancer

Student researchers get new view of the dynamics of cancer cells as they metastasize

Researchers discover new insights into how cells make transition from nonmalignant to metastatic

Study confirms that mesenchymal stem cells may help treat cancer

Biological imaging technologies create a new way to learn about cells

Surgery extends life for metastatic colorectal cancer patients

Epstein–Barr virus linked to improved gastric cancer survival

Mechanism of tumor suppressor p53 inactivation described

New risk classification system proposed for prostate cancer

Novel approach using Listeria bacteria shows promise against metastatic pancreatic cancer

XBiotech announces enrollment of first patient in Xilonix Phase III trial for treatment of cachexia

CNIO researcher-led consortium to receive MRA grant to advance research in melanoma

Research shows sophisticated genetic circuits allow individual bacterium to act on its own

Individual cancer cells in blood stream are responsible for metastases in breast cancer patients

Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

Study provides medical chemists with tools to design safer drugs, predict their side effects

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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