Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Potential genetic test for earlier Alzheimer's diagnosis

A new study published in the journal Epigenetics in February 2020 reports that changes in the methylation status of the Presenilin 1 (PSEN1) gene could help diagnose Alzheimer's disease (AD) earlier. This study shows for the first time that methylation of this gene is a common feature in AD.

1 Mar 2020

Study shows how cellular filament helps neural stem cells clear damaged, clumped proteins

New research by University of Wisconsin-Madison scientists reveals how a cellular filament helps neural stem cells clear damaged and clumped proteins, an important step in eventually producing new neurons.

28 Feb 2020

Gene-editing technology may lead to new model for studying Parkinson’s disease

Parkinson's disease researchers have used gene-editing tools to introduce the disorder's most common genetic mutation into marmoset monkey stem cells and to successfully tamp down cellular chemistry that often goes awry in Parkinson's patients.

27 Feb 2020

Human stem cells cure diabetes in mice

Diabetes is characterized by elevated levels of blood sugar and is tied to various health complications. The condition is a global health issue with the number of people with diabetes increasing from 108 million in 1980 to 422 million in 2014.

27 Feb 2020

New clinical trial uses universal natural killer cell approach to treat acute myeloid leukemia

A new, phase I clinical trial offered The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute will treat patients with relapsed or refractory acute myeloid leukemia using a novel universal natural killer cell approach.

27 Feb 2020

Stem cell discovery could open the door to new approach for bone marrow transplantation

Mount Sinai researchers have discovered a way to enhance the potency of blood-forming stem cells, potentially opening the door to a new approach for bone marrow transplantation, according to a study being published on February 27 in Cell Stem Cell.

26 Feb 2020

Aggressive cancers set up a structural framework to keep the immune system at bay

Aggressive colorectal cancers set up an interactive network of checkpoints to keep the immune system at bay, scientists report.

26 Feb 2020

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Abnormal formation and growth of the placenta is considered an underlying cause of various pregnancy complications such as miscarriages, preeclampsia and fetal growth restriction.

25 Feb 2020

Inflammation caused by radiation can promote survival of triple-negative breast cancer cells

While radiation is successfully used to treat breast cancer by killing cancer cells, inflammation caused as a side-effect of radiation can have a contrary effect by promoting the survival of triple-negative breast cancer cells, according to research published online in the International Journal of Radiation Biology by Jennifer Sims-Mourtada, Ph.D., director of Translational Breast Cancer Research at ChristianaCare's Helen F. Graham Cancer Center & Research Institute.

24 Feb 2020

Coriell researchers find new genetic indicator of obesity risk

Obesity is among the most common complex diseases in the United States and has been a stubborn public health challenge for decades. Its causes are wide ranging, but genetic heritability is increasingly understood to be an influential factor in determining a person's risk for the disease.

23 Feb 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

Using 'mini-brains' to detect harmful neurodevelopmental effects of antidepressant

Researchers at Johns Hopkins Bloomberg School of Public Health have demonstrated the use of stem-cell-derived "mini-brains" to detect harmful side effects of a common drug on the developing brain.

21 Feb 2020

Researchers map the cellular diversity of entire salivary gland tumors

What goes on inside and between individual cells during the very earliest stages of tumor development? Single cell sequencing technologies and a mouse model have enabled researchers to comprehensively map the cellular diversity of whole salivary gland tumors and trace the path of cancer stem cells.

20 Feb 2020

How does the intestine heal?

The intestine is an amazing organ in multiple ways, not least of which is its capacity to heal itself even when it is injured or damaged. Finally, a study by researchers at Dana-Farber Cancer Institute, published in the journal Cell Stem Cell shows how intestinal stem cells keep their number constant to renew the intestinal lining as and when it is required.

20 Feb 2020

UCLA researchers identify new molecule that promotes airway health

A molecule identified by UCLA researchers helps maintain a healthy balance of cells in airway and lung tissue.

18 Feb 2020

NRG Oncology trial: Hippocampal avoidance during whole-brain radiotherapy reduces risks

Results from the NRG Oncology clinical study NRG-CC001 concluded that lowering radiotherapy dose to hippocampal stem cells improves cognitive and patient-reported outcomes for patients with brain metastases.

18 Feb 2020

New 3D model shows how breast cancer cells interact with the body’s stem cells

A Loughborough University Ph.D. student has provided new insight into how breast cancer cells interact with cells in our body by using a novel 3D model.

18 Feb 2020

New understanding on how cancer cells communicate

Researchers from University College London have devised a new way by which they could decipher the language cancer cells use to communicate among themselves. They found this unique method of communication between the cancer cells in organoids or collections of cells mimicking a mini organism in the lab.

17 Feb 2020

New technology enables scientists to analyze behavior of cancer cells in lab-grown tumors

New technology developed at UCL is, for the first time, enabling cancer scientists to analyze the individual behavior of millions of different cells living inside lab-grown tumors - a breakthrough which could lead to new personalised cancer treatments.

17 Feb 2020

Fragile X syndrome-causing repeats help human neurons function, study finds

Over half of our genomes are made of repeating elements within DNA. In rare cases, these repeats can become unstable and grow in size. These repeat "expansions" cause neurodegenerative diseases such as ALS and dementia as well as learning disorders and autism in Fragile X syndrome.

17 Feb 2020

Stem Cells News and Research

Further Reading

Potential genetic test for earlier Alzheimer's diagnosis

Study shows how cellular filament helps neural stem cells clear damaged, clumped proteins

Gene-editing technology may lead to new model for studying Parkinson’s disease

Human stem cells cure diabetes in mice

New clinical trial uses universal natural killer cell approach to treat acute myeloid leukemia

Stem cell discovery could open the door to new approach for bone marrow transplantation

Aggressive cancers set up a structural framework to keep the immune system at bay

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Inflammation caused by radiation can promote survival of triple-negative breast cancer cells

Coriell researchers find new genetic indicator of obesity risk

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Using 'mini-brains' to detect harmful neurodevelopmental effects of antidepressant

Researchers map the cellular diversity of entire salivary gland tumors

How does the intestine heal?

UCLA researchers identify new molecule that promotes airway health

NRG Oncology trial: Hippocampal avoidance during whole-brain radiotherapy reduces risks

New 3D model shows how breast cancer cells interact with the body’s stem cells

New understanding on how cancer cells communicate

New technology enables scientists to analyze behavior of cancer cells in lab-grown tumors

Fragile X syndrome-causing repeats help human neurons function, study finds

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