in vivo News and Research

RSS

Phase 2/3 COVID-19 study evaluates safety, potential identification of preliminary efficacy signals

Top-line data from the 270-patient global Phase 2/3 COVID-19 study expected Q1/2021. Top-line data from the 40-patient U.S. Phase 2 study of opaganib in severe COVID-19 expected in the coming days; this non-powered study was designed to evaluate safety and potential identification of preliminary efficacy signals in support of the global Phase 2/3 study of opaganib.

23 Dec 2020

Study reveals innovative gene therapy approach to regenerate functional new neurons

Spinal cord injury (SCI) often causes disability and seriously compromises quality of life. While decades of research have made significant progress in axonal regeneration after SCI, most of the interventions have not been translated into clinical therapies.

18 Dec 2020

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Researchers from the Washington University School of Medicine, United States of America, recently demonstrated that the SARS-CoV-2 surface proteins alone triggered innate cell activity and the interferon signaling pathway.

17 Dec 2020

Gene surfing caused the SARS-CoV-2 D614G variant to rise to dominance in the US

A recent preprint that appeared on the bioRxiv* server applies a new approach to conventional birth-death lineage modeling.

17 Dec 2020

Low-intensity pulsed ultrasound combined with microbubbles might enhance chemotherapy delivery

Application of low-intensity pulsed ultrasound in combination with microbubbles might enhance the delivery of chemotherapy medication used for treating cancers.

17 Dec 2020

Mogrify solidifies IP position surrounding core technology and expands platform algorithm to enhance cell conversion

Mogrify today announced it had secured the assignment of the foundational intellectual property underpinning its core direct cell conversion technology.

17 Dec 2020

Novel method reveals the synaptic basis for feature selectivity

A common analogy used to describe the brain is that it consists of tiny interconnected computers.

17 Dec 2020

Researchers use bacterial strains to measure host gene expression in mouse model

The bacteria Streptococcus pneumoniae colonizes the nasopharynx and can cause pneumonia. Then, it can spread from the lungs to the bloodstream and cause organ damage.

16 Dec 2020

Researchers focus on preventing infections caused by carbapenemase-producing bacteria

In 2017, the World Health Organization published a list of pathogens for which new drugs are urgently needed.

16 Dec 2020

Traditional herbal medicine Respiratory Detox Shot (RDS) inhibits SARS-CoV, SARS-CoV-2 and Influenza A infection in vitro

As researchers continue to search for antivirals to counter COVID-19, a study presents the potential utility of a decoction called Respiratory Detox Shot (RDS).

16 Dec 2020

Copper gluconate supplementation could reduce SARS-CoV-2 infection in vitro

The second wave of COVID-19 has affected many countries, costing thousands of lives and dealing further heavy blows to already reeling economies.

16 Dec 2020

RedHill Biopharma announces promising preliminary results from opaganib study

TEL AVIV, Israel and RALEIGH, NC, December 15, 2020, RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced promising preliminary results from a preclinical study with opaganib.

15 Dec 2020

Research provides new insights into Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.

11 Dec 2020

68Ga-pentixafor PET imaging is an effective diagnostic tool for CNS B-cell lymphoma

Positron emission tomography (PET) imaging with 68Ga-pentixafor is an effective diagnostic tool for central nervous system (CNS) B-cell lymphoma, according to a proof-of-concept study published in the December issue of The Journal of Nuclear Medicine.

10 Dec 2020

Reverse phenotyping shows reactive T cell profiles in SARS-CoV-2 infection

A new study appearing as a preprint on the medRxiv* browser in December 2020 employs reverse phenotyping technology to explore T cell responses in COVID-19.

10 Dec 2020

Pioneering diagnostics platform changes the way COVID-19 is detected

Montreal-based Two-Photon Research Inc. announces CAST, a diagnostics platform that changes the way viruses are detected. The CAST platform uses TPR’s patented Aptamer Molecular Photonic Beacon™ that photonically interfaces with smartphones.

10 Dec 2020

New consortium aims to understand principles underlying the formation of coronaviruses

The University of California, Riverside, is the recipient of a 2021 UC Multicampus Research Programs and Initiatives, or MRPI, award allowing the campus to put together a UC Coronavirus Assembly Research Consortium.

9 Dec 2020

Researchers identify new gene variants that modify the risk of late-onset Alzheimer's disease

Late-onset Alzheimer's disease (LOAD) is the most common form of dementia in the elderly, affecting almost 44 million people worldwide.

8 Dec 2020

Researchers identify new mechanism through which plants can regulate gene expression

Just like other organisms, plants must respond dynamically to a variety of cues over their lifetime. Going through different developmental stages, or altering their form in response to a drought or drastic temperature change requires altering which of their genes are expressed into proteins and when those processes occur.

8 Dec 2020

Molecular simulations reveal that remdesivir targets two SARS-CoV-2 enzymes

Remdesivir has been shown to target both RNA-dependent RNA polymerase and main protease of SARS-CoV-2 – resulting in a ‘double whammy’ effect.

7 Dec 2020

in vivo News and Research

Phase 2/3 COVID-19 study evaluates safety, potential identification of preliminary efficacy signals

Study reveals innovative gene therapy approach to regenerate functional new neurons

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Gene surfing caused the SARS-CoV-2 D614G variant to rise to dominance in the US

Low-intensity pulsed ultrasound combined with microbubbles might enhance chemotherapy delivery

Mogrify solidifies IP position surrounding core technology and expands platform algorithm to enhance cell conversion

Novel method reveals the synaptic basis for feature selectivity

Researchers use bacterial strains to measure host gene expression in mouse model

Researchers focus on preventing infections caused by carbapenemase-producing bacteria

Traditional herbal medicine Respiratory Detox Shot (RDS) inhibits SARS-CoV, SARS-CoV-2 and Influenza A infection in vitro

Copper gluconate supplementation could reduce SARS-CoV-2 infection in vitro

RedHill Biopharma announces promising preliminary results from opaganib study

Research provides new insights into Glioblastoma invasiveness

68Ga-pentixafor PET imaging is an effective diagnostic tool for CNS B-cell lymphoma

Reverse phenotyping shows reactive T cell profiles in SARS-CoV-2 infection

Pioneering diagnostics platform changes the way COVID-19 is detected

New consortium aims to understand principles underlying the formation of coronaviruses

Researchers identify new gene variants that modify the risk of late-onset Alzheimer's disease

Researchers identify new mechanism through which plants can regulate gene expression

Molecular simulations reveal that remdesivir targets two SARS-CoV-2 enzymes

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News