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New cyber-biological attack can trick biologists into generating dangerous toxins

An end-to-end cyber-biological attack, in which unwitting biologists may be tricked into generating dangerous toxins in their labs, has been discovered by Ben-Gurion University of the Negev cyber-researchers.

30 Nov 2020

Mollusc-derived compounds potential medicines for COVID-19 and other respiratory diseases

A research team has reviewed the existing literature on compounds derived from molluscs used for treating respiratory diseases.

30 Nov 2020

Phycobilins found to inhibit SARS-CoV-2 enzymes in vitro

Researchers have released an interesting new study that describes the broad-spectrum of antiviral activity that phycobilins can have. Phycobilins, which are bioactive plant compounds, were found to inhibit two coronavirus enzymes.

26 Nov 2020

Biocompatible photooxygenation catalyst could be potentially used to treat amyloid diseases

A new, biocompatible photooxygenation catalyst that can selectively oxygenate and degrade the pathogenic aggregation of Alzheimer's disease (AD)-related amyloid-β peptide (Aβ) under near-infrared (NIR) light irradiation is developed.

25 Nov 2020

Study unravels the immunogenicity of ferroptotic cancer cells

The interdisciplinary team of scientists from three different countries (Belgium, Italy, and Russia) under the leadership of Prof. Dr. Dmitri V. Krysko (Ghent University, Belgium) unravels the immunogenicity of ferroptotic cancer cells.

25 Nov 2020

SARS-CoV-2 versus Zika: Comparing and contrasting the flow of research

An interesting study published on the preprint server medRxiv in November 2020, dealing not with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is the cause of the COVID-19 pandemic, but with the publications that have appeared as a consequence of the outbreak, comparing them with the similar trove of publications that followed the Zika virus outbreak in 2016.

25 Nov 2020

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Researchers have developed a fluorescent reporter gene-bearing recombinant form of SARS-CoV-2, which is capable of replication.

23 Nov 2020

Pomegranate peel extract shows potential as inhibitor of SARS-CoV-2 virus

Researchers led by first author Relja Suručić from the Department of Pharmacognosy, Faculty of Medicine, University of Banja Luka, Banja Luka, Bosnia and Herzegovina, have studied the use of pomegranate peel extracts in preventing infections with SARS-CoV-2.

22 Nov 2020

Study demonstrates 24-hour rat liver viability in a normothermic machine perfusion system

In a paper published in TECHNOLOGY, a team of researchers from Massachusetts General Hospital (MGH) has demonstrated 24-hour rat liver viability in a normothermic machine perfusion (NMP) system.

18 Nov 2020

Manipulating mitochondria to improve the efficiency of neuronal reprogramming

The replacement of lost neurons is a holy grail for neuroscience. A new promising approach is the conversion of glial cells into new neurons. Improving the efficiency of this conversion or reprogramming after brain injury is an important step towards developing reliable regenerative medicine therapies.

17 Nov 2020

Consumption of teff grain boosts the composition, function of stomach microbiome

The seeds of a teff plant - which look similar to wheat - are tiny in stature, but they pack a nutritional wallop.

16 Nov 2020

Neuroscientists identify astrocytes as master 'conductors' of the brain

In the orchestra of the brain, the firing of each neuron is controlled by two notes--excitatory and inhibitory-- that come from two distinct forms of a cellular structure called synapses.

12 Nov 2020

Study identifies potential treatment to postpone development of osteoarthritis

Osteoarthritis (OA), a widely acknowledged cause of disability that affects patients' quality of life and has significant economic impact through healthcare costs and loss of earnings.

12 Nov 2020

"Cat's claw" extract inhibits replication of SARS-CoV-2 in vitro

Researchers in Columbia and Peru have shown that Uncaria tomentosa – a woody vine native to South America known of as "Cat's claw" – exerts in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

12 Nov 2020

Men and women may require different brain tumor therapy, study finds

The current study shows that the sex differences in the tumor phenotype vary with the effect of the enhancer regulatory molecule bound to Brd4 on the course of stem cell-like differentiation in male and female GBM cells. Inhibition of Brd4 by genetic and pharmacological factors also varies in males and females, both in vivo and in vitro.

11 Nov 2020

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver.

11 Nov 2020

Pioneering technique sheds new light on the origin of metastases

Research can now target metastases more effectively thanks to a new approach that takes into account the enormous heterogeneity and phenotypes of tumor cells, with a team from UNIGE pinpointing a gene that prevents their development.

10 Nov 2020

Nanoparticles could treat neurodegenerative diseases, shows study

Researchers from the Institut national de la recherche scientifique (INRS) have shown that nanoparticles could be used to deliver drugs to the brain to treat neurodegenerative diseases.

10 Nov 2020

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Recently, researchers from The Johns Hopkins University School of Medicine, Baltimore, MD, USA, and Capricor Therapeutics, Inc., Beverly Hills, CA, USA, described a new approach to SARS-CoV-2 vaccine development using exosomes to deliver mRNAs that encode the antigens from multiple structural proteins of the virus.

9 Nov 2020

Novel, highly specific treatment method for hyperinsulinemic hypoglycemia

A new method to treat hyperinsulinemic hypoglycemia has proven highly selective in targeting lesions and effective in slowing tumor growth, according to research published in the November issue of the Journal of Nuclear Medicine.

9 Nov 2020

in vivo News and Research

New cyber-biological attack can trick biologists into generating dangerous toxins

Mollusc-derived compounds potential medicines for COVID-19 and other respiratory diseases

Phycobilins found to inhibit SARS-CoV-2 enzymes in vitro

Biocompatible photooxygenation catalyst could be potentially used to treat amyloid diseases

Study unravels the immunogenicity of ferroptotic cancer cells

SARS-CoV-2 versus Zika: Comparing and contrasting the flow of research

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Pomegranate peel extract shows potential as inhibitor of SARS-CoV-2 virus

Study demonstrates 24-hour rat liver viability in a normothermic machine perfusion system

Manipulating mitochondria to improve the efficiency of neuronal reprogramming

Consumption of teff grain boosts the composition, function of stomach microbiome

Neuroscientists identify astrocytes as master 'conductors' of the brain

Study identifies potential treatment to postpone development of osteoarthritis

"Cat's claw" extract inhibits replication of SARS-CoV-2 in vitro

Men and women may require different brain tumor therapy, study finds

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

Pioneering technique sheds new light on the origin of metastases

Nanoparticles could treat neurodegenerative diseases, shows study

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Novel, highly specific treatment method for hyperinsulinemic hypoglycemia

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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