Immune System News and Research

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Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

In a ground-breaking study, scientists at Children's Hospital of Pittsburgh have discovered that adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply, a previously unknown characteristic indicating that post-natal stem cells may play an important therapeutic role.

27 Jun 2005

Gleevec or similar drugs might be useful in preventing adverse side effects of smallpox vaccine

Mice given a relatively new cancer drug can survive an otherwise lethal dose of vaccinia virus, a relative of smallpox virus, report scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID).

27 Jun 2005

Scientists solve structure of a critical innate immune system protein

Scientists at The Scripps Research Institute have solved the structure of a crucial human immune system molecule called TLR3, an acronym for Toll-like receptor three. In an upcoming issue of the journal Science, the protein is described as a large horseshoe-shaped coil composed of 23 leucine-rich repeats (LRRs).

27 Jun 2005

Researchers successfully treat laboratory model of a lysosomal storage disease called GM1

Physicians might one day be able to treat a disease that destroys brain cells in children using genetically modified cells to transport a "drug" to the site of the dying neural cells (cells that transmit impulses).

27 Jun 2005

Scientists successfully isolate stem cells from human skin

Scientists at Wake Forest University School of Medicine have successfully isolated stem cells from human skin, expanded them in the laboratory and coaxed them into becoming fat, muscle and bone cells.

27 Jun 2005

Enzyme known as cathepsin G may be a target for anti-inflammatory treatments

The finding by researchers at Washington University School of Medicine in St. Louis shows that an enzyme known as cathepsin G regulates the ability of immune cells known as neutrophils to secrete chemicals that attract other immune cells and start the local inflammatory process. Over time, the excessive accumulation of immune cells can lead to tissue and cartilage damage in joints, causing pain and limiting mobility.

27 Jun 2005

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

27 Jun 2005

OHSU scientists say low FOXP3 means fewer disease-fighting cells, but new drug may help multiple sclerosis

Oregon Health & Science University researchers have measured genetic changes reflecting a drop in the body's ability to suppress inflammatory cells that attack nerve fibers and promote progression of multiple sclerosis.

27 Jun 2005

New drug delays the onset of diabetes

New research has shown that an experimental drug, designed to reset the body's immune system, could delay the need for extra insulin in some people with recently diagnosed juvenile diabetes.

23 Jun 2005

New insight into autoimmune disease

The immune system is a complex and powerful weapon that provides protection against bacteria and viruses that, if left unchecked, would wreak havoc throughout the human body.

21 Jun 2005

Partnership to develop an AIDS vaccine using a promising new technology

GlaxoSmithKline Biologicals (GSK Biologicals) and the International AIDS Vaccine Initiative (IAVI) today announced a public-private partnership to develop an AIDS vaccine using a promising new technology.

21 Jun 2005

New discoveries in treatment for patients with non-Hodgkin's lymphoma

Three scientific studies - each highlighting new discoveries in treatment for patients with non-Hodgkin's lymphoma - were announced at the Society of Nuclear Medicine's 52nd Annual Meeting June 18–22 in Toronto.

20 Jun 2005

Zebrafish provides cancer researchers powerful new insights into the development of malignant melanoma

The embryo of a tiny, silvery tropical fish found in many home aquariums is providing cancer researchers at Northwestern University Feinberg School of Medicine with powerful new insights into the development of malignant melanoma, the deadliest form of skin cancer.

20 Jun 2005

Researchers use novel cocktail of cells to coax muscle tissue to develop its own vascular network

For years, a major obstacle has dashed the hopes of creating "replacement parts" for the human body: the lack of an internal, nourishing blood system in engineered tissues. Without it, thicker tissues can't thrive, which has confined tissue engineering's practical application to thin skin, which can recruit blood vessels from underlying tissue.

20 Jun 2005

Harmless bacterium can sometimes trigger outbreaks of life-threatening meningitis

Reporting in the June 20 issue of The Journal of Experimental Medicine, a group of scientists in Paris, France led by Colin Tinsley may have discovered how a normally harmless bacterium can sometimes trigger outbreaks of life-threatening meningitis.

20 Jun 2005

Many pitfalls of aging result from either older stem cells or stem cells responding to their older environment

Older people are more prone to infections and have a higher risk of developing leukemia, and now researchers at Stanford University School of Medicine have one hint as to why that may be.

20 Jun 2005

FDA approves treatment for diarrhea caused by Cryptosporidium infection

The U.S. Food and Drug Administration (FDA) has approved Alinia (nitazoxanide) tablets and oral suspension for treating diarrhea caused by Cryptosporidium parvum infection in adults and children 12 years and older. The product, already approved to treat the same infection in younger children, received a priority review by FDA.

19 Jun 2005

Australian scientists develop unique animal model for asthma

The State Government of Victoria, Australia has announced that Melbourne veterinary scientists have developed a unique animal model for asthma that may help drug companies fast track the creation of therapies for the disease.

19 Jun 2005

Female bed-rest study will understand changes to the immune response and decreased resistance to infection in space

A bed-rest study with female participants will help scientists understand changes to the immune response and decreased resistance to infection in space.

16 Jun 2005

Findings may help scientists improve the existing vaccine for yellow fever

In one of the first molecular studies of the human antibody response to yellow fever, Howard Hughes Medical Institute (HHMI) researchers and their colleagues have found the crucial bit of virus that people's immune systems need to spot and quash this often-fatal re-emerging disease.

16 Jun 2005

Immune System News and Research

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

Gleevec or similar drugs might be useful in preventing adverse side effects of smallpox vaccine

Scientists solve structure of a critical innate immune system protein

Researchers successfully treat laboratory model of a lysosomal storage disease called GM1

Scientists successfully isolate stem cells from human skin

Enzyme known as cathepsin G may be a target for anti-inflammatory treatments

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

OHSU scientists say low FOXP3 means fewer disease-fighting cells, but new drug may help multiple sclerosis

New drug delays the onset of diabetes

New insight into autoimmune disease

Partnership to develop an AIDS vaccine using a promising new technology

New discoveries in treatment for patients with non-Hodgkin's lymphoma

Zebrafish provides cancer researchers powerful new insights into the development of malignant melanoma

Researchers use novel cocktail of cells to coax muscle tissue to develop its own vascular network

Harmless bacterium can sometimes trigger outbreaks of life-threatening meningitis

Many pitfalls of aging result from either older stem cells or stem cells responding to their older environment

FDA approves treatment for diarrhea caused by Cryptosporidium infection

Australian scientists develop unique animal model for asthma

Female bed-rest study will understand changes to the immune response and decreased resistance to infection in space

Findings may help scientists improve the existing vaccine for yellow fever

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