Immune System News and Research

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Bioartificial kidney containing billions of donor kidney cells under study at the Medical College of Georgia

Whether a bioartificial kidney containing billions of donor kidney cells will help intensive care patients with kidney failure survive is under study at the Medical College of Georgia.

31 Jan 2005

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine will begin in the Washington, DC area in a couple of months after the U.S. Food and Drug Administration conferred investigational new drug status on the vaccine.

27 Jan 2005

Trial of Etanercept for Wegners's disease shows no benefit against the autoimmune condition

A Johns Hopkins-led study designed to evaluate the ability of etanercept to maintain disease remissions in a serious autoimmune disorder has failed to show any benefit. Etanercept, also called Enbrel, is a common treatment for rheumatoid arthritis and other types of joint inflammation.

26 Jan 2005

Painful surgical adhesions may be preventable by taking the COX-2 inhibitor Celebrex

Adhesions – bands of scar tissue that bind together two internal body surfaces – develop in 55 percent to more than 90 percent of patients undergoing surgery, depending on the type of operation. They are part of normal healing, but when surfaces fuse together that shouldn't, serious pain and complications can result.

26 Jan 2005

Exposure to infant siblings decreases multiple sclerosis risk

Adults who report having had higher exposure to infant siblings during their first 6 years of life have a reduced risk of multiple sclerosis (MS), according to a study in the January 26 issue of JAMA.

26 Jan 2005

Research may provide the basis for development of a new, extensive immunotherapy for human tumors

Scientists have made significant progress towards understanding how the immune system can be more specifically and efficiently targeted against cancer cells. The research, published in the January issue of Immunity, may provide the basis for development of a new, extensive immunotherapy for human tumors.

26 Jan 2005

Genzyme files Glucocerebrosidase patent infringement

Genzyme announced today that it has filed a lawsuit in the District Court of Tel Aviv alleging that Transkaryotic Therapies Inc. has infringed Genzyme's Israeli patent No. 100,715, which covers certain cell culture processes involved in the manufacture of glucocerebrosidase.

25 Jan 2005

New technique can greatly facilitate the development of vaccines against infectious diseases such as smallpox, malaria and tuberculosis

Because the new technique can synthesize a large number of proteins very quickly, it has potential to accelerate vaccine development, particularly crucial in the fight against bioterrorism.

25 Jan 2005

Available lines of human embryonic stem cells have been contaminated

Currently available lines of human embryonic stem cells have been contaminated with a non-human molecule that compromises their potential therapeutic use in human subjects, according to research by investigators at the University of California, San Diego (UCSD) School of Medicine and the Salk Institute in La Jolla, California.

24 Jan 2005

Activate dendritic cells turn on biological clock

A molecule specially modified by researchers at Baylor College of Medicine can reset the biological clock for cancer vaccines, potentially making them more potent.

24 Jan 2005

Aircraft drinking water contaminated with bacteria

A second round of Environmental Protection Agency (EPA) testing shows that 17.2 percent of 169 randomly selected passenger aircraft carried water contaminated with total coliform bacteria.

19 Jan 2005

NIH begins Phase 1 clinical trial of HIV vaccine candidate

GenVec announced today that the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), has begun the second Phase 1 clinical trial in healthy adult volunteers of an HIV vaccine candidate jointly developed by the Dale and Betty Bumpers Vaccine Research Center (VRC), a part of NIAID, and GenVec.

19 Jan 2005

Newly discovered virus, New Haven coronavirus

A newly discovered virus may be responsible for many respiratory tract illnesses in infants and children, and may be associated with an important multi-organ disease whose cause has remained a mystery for decades, according to articles in the Feb. 15 issue of The Journal of Infectious Diseases, now available online.

19 Jan 2005

Jump starting T cells in skin cancer

Advanced melanoma, the most deadly form of skin cancer, can be successfully treated in some cases by vaccinating patients with tumor proteins.

17 Jan 2005

Researchers have identified the cellular receptor for the JC virus

Researchers funded in part by the National Institute of Neurological Disorders and Stroke (NINDS) have identified the cellular receptor for the JC virus, which causes the fatal neurological disease progressive multifocal leukoencephalopathy (PML).

17 Jan 2005

Scientists are a step closer to developing drug targets to treat fungal meningitis

Scientists are a step closer to developing drug targets to treat fungal meningitis -- the infection linked to at least three deaths on Vancouver Island -- thanks to the sequencing of two Cryptococcus genomes by an international team that included researchers at the University of British Columbia and the BC Cancer Agency's Michael Smith Genome Sciences Centre in Vancouver.

17 Jan 2005

FDA licenses Sanofi pasteur vaccine for protection against meningococcal disease

Sanofi pasteur, the vaccines business of the sanofi-aventis Group, announced today that the U.S. Food and Drug Administration (FDA) has licensed Menactra (Meningococcal [Groups A, C, Y and W-135] Polysaccharide Diphtheria Toxoid Conjugate Vaccine) for protection against meningococcal disease in adolescents and adults aged 11-55 years.

17 Jan 2005

Gene transfer used to deliver antibodies to fight Anthrax

Using gene transfer technology, investigators were able to immunize mice against anthrax in just 12 hours, according to new research featured in the February 2005 issue of Molecular Therapy, the peer-reviewed scientific journal of the American Society of Gene Therapy (ASGT).

12 Jan 2005

Major partnership with National Institute of Allergy and Infectious Diseases for Narhex Life Sciences

Australian drug specialist Narhex Life Sciences, has announced a partnership with one of the world’s foremost US medical research centres to evaluate its protease inhibitor Nar DG 35 Prodrug for its activity against Hepatitis C and SARS viruses.

12 Jan 2005

Scientists uncover new evidence to help explain statins’ effects in Alzheimer’s disease

Scientists at Jefferson Medical College and the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia have taken another step in understanding the potential effects of anti-cholesterol drugs on Alzheimer’s disease.

12 Jan 2005

Immune System News and Research

Bioartificial kidney containing billions of donor kidney cells under study at the Medical College of Georgia

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine

Trial of Etanercept for Wegners's disease shows no benefit against the autoimmune condition

Painful surgical adhesions may be preventable by taking the COX-2 inhibitor Celebrex

Exposure to infant siblings decreases multiple sclerosis risk

Research may provide the basis for development of a new, extensive immunotherapy for human tumors

Genzyme files Glucocerebrosidase patent infringement

New technique can greatly facilitate the development of vaccines against infectious diseases such as smallpox, malaria and tuberculosis

Available lines of human embryonic stem cells have been contaminated

Activate dendritic cells turn on biological clock

Aircraft drinking water contaminated with bacteria

NIH begins Phase 1 clinical trial of HIV vaccine candidate

Newly discovered virus, New Haven coronavirus

Jump starting T cells in skin cancer

Researchers have identified the cellular receptor for the JC virus

Scientists are a step closer to developing drug targets to treat fungal meningitis

FDA licenses Sanofi pasteur vaccine for protection against meningococcal disease

Gene transfer used to deliver antibodies to fight Anthrax

Major partnership with National Institute of Allergy and Infectious Diseases for Narhex Life Sciences

Scientists uncover new evidence to help explain statins’ effects in Alzheimer’s disease

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