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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Scientists develop world's first test to accurately predict mood disorders

University of South Australia scientists have developed the world's first test to accurately predict mood disorders in people, based on the levels of a specific protein found in the brain.

19 Jan 2021

SARS-CoV-2 RNA in blood serum could predict COVID-19 mortality

Researchers find that the presence of SARS-CoV-2's genetic material in the serum of positive patients could be a sturdy biomarker for predicting COVID-19-related mortality.

18 Jan 2021

Could procalcitonin indicate bacterial co-infections in COVID-19 patients?

A recent study conducted by Austin Health, Australia, has revealed that the serum level of procalcitonin can be a strong indicator of bacterial co-infection with COVID-19.

18 Jan 2021

Midwife’s research included in new national guidance on harms caused by alcohol in pregnancy

As thousands of people are committing to giving up alcohol during Dry January, research from a midwifery lecturer at Northumbria University has been included in new national guidance on the harms of consuming alcohol both before and during pregnancy.

18 Jan 2021

Targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers

Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response.

15 Jan 2021

Researchers demonstrate great potential for blood test to detect, monitor Alzheimer's disease

In three recent publications in Molecular Psychiatry, Brain and JAMA Neurology researchers from the University of Gothenburg provide convincing evidence that an in-house developed blood test for Alzheimer's disease can detect the disease early and track its course, which has major implications for a potential use in clinical practice and treatment trials.

14 Jan 2021

Researchers use urine test to identify and verify a patient's type of asthma

In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient's type of asthma.

13 Jan 2021

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

Glioblastoma brain tumors are especially perplexing. Inevitably lethal, the tumors occasionally respond to new immunotherapies after they've grown back, enabling up to 20% of patients to live well beyond predicted survival times.

13 Jan 2021

Researchers investigate protein phosphatase to identify new treatments for cancer, other diseases

The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential.

13 Jan 2021

ADC histogram analysis can predict tumor proliferation, survival in immunocompetent patients with PCNSL

The cover for issue 45 of Oncotarget features Figure 3, "Representative images of whole tumor volume segmentation of the co-registered T1 post-contrast sequence and apparent diffusion coefficient (ADC) map, yielding the corresponding ADC histogram distribution utilized for data analysis," recently published in "Diffusion-weighted MR imaging histogram analysis in HIV positive and negative patients with primary central nervous system lymphoma as a predictor of outcome and tumor proliferation" by Khan, et al.

12 Jan 2021

Study: 20% of glioblastomas are fueled by overactive mitochondria

A new study has found that up to 20% of glioblastomas--an aggressive brain cancer--are fueled by overactive mitochondria and may be treatable with drugs currently in clinical trials.

11 Jan 2021

Researchers identify biomarkers in sperm for paternal offspring autism susceptibility

Biomarkers in human sperm have been identified that can indicate a propensity to father children with autism spectrum disorder.

11 Jan 2021

Bruker and Evosep announce major progress in unbiased, quantitative true single-cell proteomics

Bruker Corporation and Evosep today announced major progress in high-sensitivity, quantitative true single-cell proteomics, using a modified timsTOF Pro mass spectrometer connected to an Evosep One low-flow chromatography system.

From Bruker Daltonics 8 Jan 2021

Proteogenomics can help determine effective treatment for head and neck squamous cell carcinoma

Proteogenomic analysis may offer new insight into matching cancer patients with an effective therapy for their particular cancer.

7 Jan 2021

Researchers provide comprehensive molecular characterization of head and neck cancers

In what is believed to be the most comprehensive molecular characterization to date of the most common type of head and neck cancer, researchers from the Johns Hopkins departments of pathology and oncology, the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine, and 18 other centers around the U.S. and Poland have clarified the contribution of key cancer-associated genes, proteins and signaling pathways in these cancers, while proposing possible new treatment avenues.

7 Jan 2021

Researchers receive $2.95 million grant to create improved diagnostics for worm infections

Global campaigns to eliminate two tropical parasitic worm infections have been hindered by a lack of good diagnostic tools.

7 Jan 2021

Using a blood test to predict Alzheimer's disease risk during symptom-free stage

Using a blood test, a German-Dutch research team has predicted the risk of Alzheimer's disease in people who were clinically diagnosed as not having Alzheimer's disease but who perceived themselves as cognitively impaired (Subjective Cognitive Declined, SCD).

6 Jan 2021

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it.

5 Jan 2021

P2 COVID-19 study shows no material safety differences between opaganib and control arms

Preliminary data from the non-powered U.S. Phase 2 study of 40 hospitalized patients shows that orally-administered opaganib was safe, with no material safety differences between opaganib and control arms.

4 Jan 2021

Brain scans predict posttraumatic stress disorder following mild TBI

Posttraumatic stress disorder (PTSD) is a complex psychiatric disorder brought on by physical and/or psychological trauma. How its symptoms, including anxiety, depression and cognitive disturbances arise remains incompletely understood and unpredictable.

29 Dec 2020

Biomarker News and Research

Further Reading

Scientists develop world's first test to accurately predict mood disorders

SARS-CoV-2 RNA in blood serum could predict COVID-19 mortality

Could procalcitonin indicate bacterial co-infections in COVID-19 patients?

Midwife’s research included in new national guidance on harms caused by alcohol in pregnancy

Targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers

Researchers demonstrate great potential for blood test to detect, monitor Alzheimer's disease

Researchers use urine test to identify and verify a patient's type of asthma

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

Researchers investigate protein phosphatase to identify new treatments for cancer, other diseases

ADC histogram analysis can predict tumor proliferation, survival in immunocompetent patients with PCNSL

Study: 20% of glioblastomas are fueled by overactive mitochondria

Researchers identify biomarkers in sperm for paternal offspring autism susceptibility

Bruker and Evosep announce major progress in unbiased, quantitative true single-cell proteomics

Proteogenomics can help determine effective treatment for head and neck squamous cell carcinoma

Researchers provide comprehensive molecular characterization of head and neck cancers

Researchers receive $2.95 million grant to create improved diagnostics for worm infections

Using a blood test to predict Alzheimer's disease risk during symptom-free stage

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

P2 COVID-19 study shows no material safety differences between opaganib and control arms

Brain scans predict posttraumatic stress disorder following mild TBI

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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