Cell Death News and Research

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Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine.

7 Dec 2016

Brazilian researchers propose new way for treating thalassemia major

Iron accumulation in myocardial cells, potentially resulting in heart failure or fatal arrhythmia, is one of the complications most feared by patients with thalassemia major, a hereditary disease also known as Mediterranean anemia.

7 Dec 2016

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found.

7 Dec 2016

Researchers identify critical paralog groups with indispensable role in cellular signalling pathways

Throughout evolutionary history, there have been genetic elements that have duplicated - giving rise to genes with different functions.

7 Dec 2016

NIH scientists unravel chain of events that lead to fatal outcomes in cerebral malaria

Using state-of-the-art brain imaging technology, scientists at the National Institutes of Health filmed what happens in the brains of mice that developed cerebral malaria (CM).

6 Dec 2016

Study highlights requirement of protein in initiation of apoptosis in uveal melanoma

New research from the University of Liverpool has identified the role of a specific protein in the human body that can help prevent the survival and spread of eye cancer, by initiating cancer 'cell-suicide'.

6 Dec 2016

New drug treatment can override genetic fault that causes choroideremia

Researchers with funding from Fight for Sight have demonstrated that a new drug treatment for cystic fibrosis and Duchenne muscular dystrophy can override a genetic fault that causes choroideremia – a severe blinding disorder.

5 Dec 2016

Scientists discover unique genomic changes integral to testicular cancer development

Researchers led by scientists at Dana-Farber Cancer Institute say they have identified unique genomic changes that may be integral to testicular cancer development and explain why the great majority are highly curable with chemotherapy - unlike most solid tumors.

1 Dec 2016

Study suggests new approach to treat white blood cells of sepsis patients

New research findings published in the Journal of Leukocyte Biology, suggest that treating the white blood cells of sepsis patients with antibodies that block programmed cell death-1 (PD-1) and programmed cell death ligand (PD-L1) molecules may restore their function and ultimately their ability to eradicate deadly bacteria.

1 Dec 2016

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Researchers of the Sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, have first described the methylation profile of Ewing's sarcoma, a cancer of bone and soft tissues that mainly affects children and teenagers.

1 Dec 2016

Study sheds light on why new drug is effective in combating leukaemia

Researchers at the University of Southampton have shed new light on why and how a new class of drug is effective at fighting off leukaemia.

29 Nov 2016

Researchers uncover new clues that may help combat leukemia and other B cell cancers

When B lymphocytes (a type of white blood cell in the immune system geared for fighting diseases) turn cancerous, they become part of the problem, and need to be eliminated.

22 Nov 2016

TMDU researchers identify novel type of cell death in Huntington's disease

In Huntington's disease (HD), the huntingtin gene is mutated, causing progressive neuronal death.

22 Nov 2016

Blocking key nutrient uptake may be effective way of treating triple negative breast cancer

Cancer rewires the metabolism of tumor cells, converting them into lean, mean, replicating machines.

21 Nov 2016

Scientists uncover novel process by which APOL1 gene contributes to renal disease

A Children's National Health System research team has uncovered a novel process by which the gene APOL1 contributes to renal disease, according to a paper published November 18 in the Journal of the American Society of Nephrology.

18 Nov 2016

Study finds way to detect early signs of AD by looking at retina of patients' eyes

A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain.

18 Nov 2016

BAG3 protein plays protective role by limiting reperfusion injury to the heart

The inability of cells to eliminate damaged proteins and organelles following the blockage of a coronary artery and its subsequent re-opening with angioplasty or medications - a sequence known as ischemia/reperfusion - often results in irreparable damage to the heart muscle.

17 Nov 2016

British and Malaysian scientists develop new, nontoxic copper catalyst for click chemistry in living organisms

Assembling a drug from harmless components at the target location, such as a tumor, would help reduce the side effects of treatment.

16 Nov 2016

International scientists unravel mystery of newly discovered type of controlled cell death

A multidisciplinary international team of scientists solved the mystery of a recently discovered type of controlled cell death, mapping the path to potential therapies for conditions ranging from radiation injury to cancer.

15 Nov 2016

Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Scientists at the University of Sussex, trying to uncover how the common Epstein-Barr virus causes blood cancer in adults and children, have discovered how the virus takes control of two genes involved in cancer development so it can switch them on or off.

10 Nov 2016

Cell Death News and Research

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Brazilian researchers propose new way for treating thalassemia major

Enzyme that cleaves beta carotene may control testosterone levels

Researchers identify critical paralog groups with indispensable role in cellular signalling pathways

NIH scientists unravel chain of events that lead to fatal outcomes in cerebral malaria

Study highlights requirement of protein in initiation of apoptosis in uveal melanoma

New drug treatment can override genetic fault that causes choroideremia

Scientists discover unique genomic changes integral to testicular cancer development

Study suggests new approach to treat white blood cells of sepsis patients

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Study sheds light on why new drug is effective in combating leukaemia

Researchers uncover new clues that may help combat leukemia and other B cell cancers

TMDU researchers identify novel type of cell death in Huntington's disease

Blocking key nutrient uptake may be effective way of treating triple negative breast cancer

Scientists uncover novel process by which APOL1 gene contributes to renal disease

Study finds way to detect early signs of AD by looking at retina of patients' eyes

BAG3 protein plays protective role by limiting reperfusion injury to the heart

British and Malaysian scientists develop new, nontoxic copper catalyst for click chemistry in living organisms

International scientists unravel mystery of newly discovered type of controlled cell death

Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics