Central Nervous System News and Research

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Otsuka Pharmaceutical to acquire Avanir Pharmaceuticals for $3.5B

Avanir Pharmaceuticals, Inc. today announced that it has entered into a definitive agreement with Otsuka Pharmaceutical Co., Ltd. pursuant to which Otsuka will acquire Avanir for $17.00 per share in cash.

2 Dec 2014

Ligand indazole chloride improves motor function, study shows

Multiple sclerosis (MS), an autoimmune disease of the brain and spinal cord, affects about 2.3 million people worldwide (400,000 in the United States). Affecting more women than men, it can be seen at any age, although it is most commonly diagnosed between the ages of 20 and 40.

2 Dec 2014

DFG to establish eight new Collaborative Research Centres

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) will establish eight new Collaborative Research Centres (CRCs).

2 Dec 2014

DFG to establish new Collaborative Research Centres

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) will establish eight new Collaborative Research Centres (CRCs).

29 Nov 2014

Researchers say that nervous system may play vital role in infections, autoimmune diseases

The nervous system may play a bigger role in infections and autoimmune diseases than previously known. If researchers can learn more about that role, it could provide insight into diagnosing and treating everything from the stomach flu to rheumatoid arthritis.

27 Nov 2014

Adults diagnosed with retinoblastoma as infants perform better on tasks, study finds

Most long-term survivors of retinoblastoma, particularly those who had been diagnosed with tumors by their first birthdays, have normal cognitive function as adults, according to a St. Jude Children's Research Hospital study. The research, which appears in the current issue of the journal Cancer, found that the vast majority of survivors work full time, live independently and fulfill other milestones of adult life.

25 Nov 2014

Researchers take major step in fight against sleeping sickness

Researchers from Aarhus University have taken an important step in the fight against sleeping sickness, a disease that is a major problem in parts of Africa. According to the World Health Organization, the disease threatens approximately 60 million people and the treatment options are poor.

24 Nov 2014

NUS researchers make breakthrough discovery that could lead to future treatment for multiple sclerosis

A multi-disciplinary research team from the National University of Singapore has made a breakthrough discovery of a new type of immune cells that may help in the development of a future treatment for multiple sclerosis (MS).

24 Nov 2014

Research shows that immune checkpoint inhibitors may work in glioblastoma, brain metastases

New evidence that immune checkpoint inhibitors may work in glioblastoma and brain metastases was presented today by Dr Anna Sophie Berghoff at the ESMO Symposium on Immuno-Oncology 2014 in Geneva, Switzerland.

23 Nov 2014

Aequus Pharmaceuticals closes $4.2M private placement offering of special warrants

Aequus Pharmaceuticals Inc. (the "Company" or "Aequus") is pleased to announce that it has closed a brokered private placement offering (the "Brokered Offering") of special warrants for approximately C$3.7 million.

21 Nov 2014

Study shows how anesthesia affects cells in central nervous system

Anesthesia, long considered a blessing to patients and surgeons, has been a mystery for much of its 160-plus-year history in the operating room.

14 Nov 2014

Scientists receive NARSAD Distinguished Investigator Grants for mental health research

The Brain & Behavior Research Foundation today announced the award of NARSAD Distinguished Investigator Grants valued at $1.5 million to 15 scientists, who are full professors or the equivalent, conducting innovative projects in diverse areas of neurobiological and behavioral research.

13 Nov 2014

Researchers identify key protein that can reduce severity of disease equivalent to MS in mice

In multiple sclerosis, the immune system goes rogue, improperly attacking the body's own central nervous system. Mobility problems and cognitive impairments may arise as the nerve cells become damaged.

12 Nov 2014

Living with multiple sclerosis (MS): an interview with Gretchen Rubin and Megan Weigel

Multiple sclerosis, or MS, is a chronic, often disabling disease of the central nervous system, which is made up of the brain, spinal cord, and optic nerves. Symptoms may be mild, moderate, or severe, ranging from numbness in the limbs to paralysis or loss of vision. Approximately 400,000 Americans are living with MS.

9 Nov 2014

Cellular-level changes in nerve structure and function may contribute to migraine headaches

A new study shows cellular-level changes in nerve structure and function that may contribute to the development of migraine headaches, reports the November issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

4 Nov 2014

MSD announces Phase 2b results of doravirine therapy in untreated patients with HIV-1 infection

Merck Sharp & Dohme Ltd. MSD (known as Merck & Co., Inc. in the United States and Canada), today announced the presentation of results from a Phase 2b clinical trial evaluating the safety and efficacy of once daily oral doravirine, an investigational next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), plus tenofovir/emtricitabine (TDF/FTC) compared to efavirenz plus TDF/FTC in previously untreated patients with HIV-1 infection.

4 Nov 2014

NeuroDerm launches initial public offering of 4,500,000 shares

NeuroDerm Ltd., a clinical stage pharmaceutical company developing drugs for central nervous system (CNS) diseases, today announced the launch of its initial public offering of 4,500,000 ordinary shares pursuant to a registration statement on Form F-1 filed with the U.S. Securities and Exchange Commission (SEC).

3 Nov 2014

Nanostructures around brain cells may have role in central nervous system function

An accumulation of a protein called amyloid-beta into large insoluble deposits called plaques is known to cause Alzheimer's disease. One aspect of this illness that has not received much attention is which role the structure of the brain environment plays.

30 Oct 2014

New international consortium to advance GPCR research for drug development

The generation of high-resolution pictures of hundreds of medically important proteins known as G-protein coupled receptors (GPCRs) will be the goal of an ambitious new international partnership. Called the GPCR Consortium, this non-profit initiative brings together major pharmaceutical companies and leading research institutes from three continents to advance GPCR research for drug development.

29 Oct 2014

Growth factor boosts natural defence against auto-immune diseases

Our immune system defends us from harmful bacteria and viruses, but, if left unchecked, the cells that destroy those invaders can turn on the body itself, causing auto-immune diseases like type-1 diabetes or multiple sclerosis. A molecule called insulin-like growth factor-1 (IGF-1) boosts the body's natural defence against this 'friendly fire', scientists at the European Molecular Biology Laboratory in Monterotondo, Italy, have found.

25 Oct 2014

Central Nervous System News and Research

Otsuka Pharmaceutical to acquire Avanir Pharmaceuticals for $3.5B

Ligand indazole chloride improves motor function, study shows

DFG to establish eight new Collaborative Research Centres

DFG to establish new Collaborative Research Centres

Researchers say that nervous system may play vital role in infections, autoimmune diseases

Adults diagnosed with retinoblastoma as infants perform better on tasks, study finds

Researchers take major step in fight against sleeping sickness

NUS researchers make breakthrough discovery that could lead to future treatment for multiple sclerosis

Research shows that immune checkpoint inhibitors may work in glioblastoma, brain metastases

Aequus Pharmaceuticals closes $4.2M private placement offering of special warrants

Study shows how anesthesia affects cells in central nervous system

Scientists receive NARSAD Distinguished Investigator Grants for mental health research

Researchers identify key protein that can reduce severity of disease equivalent to MS in mice

Living with multiple sclerosis (MS): an interview with Gretchen Rubin and Megan Weigel

Cellular-level changes in nerve structure and function may contribute to migraine headaches

MSD announces Phase 2b results of doravirine therapy in untreated patients with HIV-1 infection

NeuroDerm launches initial public offering of 4,500,000 shares

Nanostructures around brain cells may have role in central nervous system function

New international consortium to advance GPCR research for drug development

Growth factor boosts natural defence against auto-immune diseases

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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