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Scientists identify potential treatment for previously unknown condition affecting children

Researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS), and Rady Children's Institute for Genomic Medicine identified a previously unknown condition affecting children, which they discovered could be prevented by administering a drug during pregnancy.

2 Oct 2021

Two-mAb cocktail prevents SARS-CoV-2 infection, study suggests

A promising study shows that a combination of two monoclonal antibodies effectively neutralized SARS-CoV-2 in monkeys and proved efficacious against newer variants of concern in vitro.

1 Oct 2021

Enveloped virus-like particle based vaccines potentially broaden immunity against SARS-CoV-2 variants

A new preprint describes promising results with a novel vaccine candidate designed to improve the breadth of neutralization.

1 Oct 2021

Scientists find new possibilities for treatment of lung cancers in 'never smokers'

Despite smoking's well-known role in causing lung cancer, a significant number of patients who develop lung tumors have never smoked. While scientists are still working to understand what spurs cancer in so-called "never-smokers," a study led by scientists at Washington University School of Medicine in St. Louis demonstrates new possibilities for treating these baffling tumors.

1 Oct 2021

Research points the way to identifying new precision treatments for cancer

Researchers at University of California San Diego and University of California San Francisco have mapped out how hundreds of mutations involved in two types of cancer affect the activity of discrete groups of proteins that are the ultimate actors behind the disease.

30 Sep 2021

Researchers discover how a genetic mutation in mice and monkeys interferes with viruses

A nationwide team of researchers, led by scientists at University of Utah Health and The Rockefeller University, has determined how a genetic mutation found in mice and monkeys interferes with viruses such as HIV and Ebola.

30 Sep 2021

Research points to new opportunities to prevent treatment resistance in fragile X syndrome

Mark Bear, Picower Professor of Neuroscience at MIT, recalls the "eureka moment" 20 years ago when he realized that a severe developmental brain disorder - fragile X syndrome - might be treated with drugs that inhibit a neurotransmitter receptor called mGluR5.

29 Sep 2021

Researchers find potential cure for a previously unknown childhood genetic condition

Describing a previously unknown genetic condition that affects children, researchers at University of California San Diego School of Medicine and Rady Children's Institute for Genomic Medicine say they also found a potential method to prevent the gene mutation by administering a drug during pregnancy.

29 Sep 2021

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

A team of researchers studied the two main viroporins of SARS-CoV-2, namely Orf3a and Envelope (E) protein, from a structural viewpoint.

29 Sep 2021

Large-scale SARS-CoV-2 spike protein mutants analysis identifies subclonal variants indicative of within-host viral diversity

Researchers have investigated a vast SARS-CoV-2 assembly and NGS data set to detect non-synonymous S protein mutations.

29 Sep 2021

Aging may not be due to build-up of mutations alone, study suggests

New research exploring theories of ageing has found that small mutations accumulating in DNA are unlikely to be fully responsible for this process.

29 Sep 2021

Exposure to smoking and mutations in blood cells may lead to a rare cancer that affects immune cells

Mutations in blood cells likely caused by smoking and aging-related changes may lead to a rare type of blood cancer that affects immune cells, shows a study published today in eLife.

28 Sep 2021

New findings highlight the need to expand the toolbox to fight against COVID-19

When Kamlendra Singh flew back to Missouri from India in April, he developed a cough and fever on the plane, despite being vaccinated for COVID-19 and testing negative for the virus right before departure.

28 Sep 2021

Researchers create an integrated pipeline for performing genetic screening studies

Today's genetic engineers have a plethora of resources at their disposal: an ever-increasing number of massive datasets available online, highly precise gene editing tools like CRISPR, and cheap gene sequencing methods. But the proliferation of new technologies has not come with a clear roadmap to help researchers figure out which genes to target, which tools to use, and how to interpret their results. So, a team of scientists and engineers at Harvard's Wyss Institute for Biologically Inspired Engineering, Harvard Medical School (HMS), and the MIT Media Lab decided to make one.

28 Sep 2021

Confinement drastically reduced the transmission of COVID-19 variants in Spain during first wave

The most complete studies on the variants of the coronavirus that dominated the first waves in Spain have just been published in Nature Genetics. The study was carried out by the SeqCOVID consortium, which includes more than 50 Spanish institutions led by the University of Valencia, the Institute of Biomedicine of Valencia (IBV, CSIC), and the Fisabio Foundation.

28 Sep 2021

New discovery greatly improves detection of HPV in the bloodstream

Princess Margaret Cancer Centre researchers have made new findings which greatly improve detection of the human papillomavirus (HPV) in the bloodstream and could further hone precision treatment of the illness.

27 Sep 2021

An in-depth assessment into origin and spread of SARS-CoV-2 Delta variant in Brazil

Brazilian researchers characterize the dissemination of the Delta VOC in Brazil and assess its emergence within the global Delta phylogeny.

27 Sep 2021

New study clears a pharmacologic hurdle in developing molecularly targeted therapies for AML

New research from Johns Hopkins Kimmel Cancer Center investigators shows why some drugs in clinical trials for treating a form of acute myeloid leukemia (AML) often fail and demonstrates a way to restore their effectiveness.

27 Sep 2021

Chronic COVID-19 and divergent variants of SARS-CoV-2

A new study discusses the isolation of two variants of concern (VOCs) from an immunocompromised COVID-19 patient.

27 Sep 2021

Mayo Clinic internist advocates a comprehensive approach to breast cancer prevention

A commentary by Mayo Clinic Cancer Center researchers published in the Journal of Clinical Oncology Practice suggests that advances in breast cancer prevention research have resulted in new and innovative opportunities to modify breast cancer risk and potentially reduce breast cancer incidence and mortality.

27 Sep 2021

Mutation News and Research

Scientists identify potential treatment for previously unknown condition affecting children

Two-mAb cocktail prevents SARS-CoV-2 infection, study suggests

Enveloped virus-like particle based vaccines potentially broaden immunity against SARS-CoV-2 variants

Scientists find new possibilities for treatment of lung cancers in 'never smokers'

Research points the way to identifying new precision treatments for cancer

Researchers discover how a genetic mutation in mice and monkeys interferes with viruses

Research points to new opportunities to prevent treatment resistance in fragile X syndrome

Researchers find potential cure for a previously unknown childhood genetic condition

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

Large-scale SARS-CoV-2 spike protein mutants analysis identifies subclonal variants indicative of within-host viral diversity

Aging may not be due to build-up of mutations alone, study suggests

Exposure to smoking and mutations in blood cells may lead to a rare cancer that affects immune cells

New findings highlight the need to expand the toolbox to fight against COVID-19

Researchers create an integrated pipeline for performing genetic screening studies

Confinement drastically reduced the transmission of COVID-19 variants in Spain during first wave

New discovery greatly improves detection of HPV in the bloodstream

An in-depth assessment into origin and spread of SARS-CoV-2 Delta variant in Brazil

New study clears a pharmacologic hurdle in developing molecularly targeted therapies for AML

Chronic COVID-19 and divergent variants of SARS-CoV-2

Mayo Clinic internist advocates a comprehensive approach to breast cancer prevention

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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