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Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Preclinical trials indicate that a drug candidate called OxaliTex can stop the growth of cancer cells completely. OxaliTex appears to be more potent than many other common chemotherapy drugs, with less toxicity and less rapidly counteracted by mechanisms of drug resistance. The study was reported in the journal Proceedings of the National Academy of Sciences in March 2020.

16 Mar 2020

Study provides new insights into brain evolution

Their researches on the lamprey brain has enabled researchers at Karolinska Institutet in Sweden to push the birth of the cortex back in time by some 300 million years to over 500 million years ago, providing new insights into brain evolution.

16 Mar 2020

Researchers discover a new mechanism of long-lasting pain relief

A group of researchers from Charité - Universitätsmedizin Berlin has discovered a new mechanism of long-lasting pain relief.

16 Mar 2020

Scientists discover link between Parkinson's and gene targeted by blue-green algae toxin

Scientists have discovered a possible link between Parkinson's disease and a gene impacted by a neurotoxin found in blue-green algae.

16 Mar 2020

Researchers reveal nerve circuitry regulating worms' response to changing temperatures

Nagoya University researchers and colleagues have revealed the nerve circuitry regulating the response of a tiny soil worm to changing temperatures.

13 Mar 2020

No evidence of a link between surgery with anesthesia and Alzheimer's disease

Older adults who have surgery with general anesthesia may experience a modest acceleration of cognitive decline, even years later. But there's no evidence of a link to Alzheimer's disease, according to new research from Mayo Clinic.

12 Mar 2020

New two-step technique to repair herniated discs

A new two-step technique to repair herniated discs uses hyaluronic acid gel to re-inflate the disc and collagen gel to seal the hole, essentially repairing ruptured discs like you'd repair a flat tire.

11 Mar 2020

Fight for Sight funded researcher develops gene therapy approach for glaucoma

A Fight for Sight funded researcher from the University of Bristol has used gene editing techniques to successfully demonstrate a gene therapy for glaucoma in the lab, in results published in Molecular Therapy in March.

11 Mar 2020

Virtual reality could aid in early detection of MS balance problems

People with multiple sclerosis (MS) often have a greatly increased risk of falling and injuring themselves even when they feel they're able to walk normally.

11 Mar 2020

Study shows JNK protein as a stress sensor in synapses

New study from Eleanor Coffey's lab at Turku Bioscience Centre in Finland identifies that the JNK protein triggers nerve cells to withdraw their synapses when stressed.

11 Mar 2020

Exploring the biological link between reactivated HSV and neurological disease

Without even knowing it, most of us carry around latent Herpes Simplex Virus in our nervous system- a simple result of being born and living together with others carrying the virus.

10 Mar 2020

Perineuronal nets control cerebellar plasticity and associative memories

Researchers at the Netherlands Institute for Neuroscience have shown that specialized aggregates of molecules enwrapping nerve cells in the brain, the perineuronal nets, are crucial for regulating the connections between nerve cells that control motor memories.

10 Mar 2020

Modern virtual and augmented reality device can be used to simulate visual impairments

Published today, during World Glaucoma Week 2020, a new study demonstrates how commercially available head mounted displays can be used to simulate the day-to-day challenges faced by people with glaucoma.

10 Mar 2020

UQ study identifies a major shift in how to treat brain injuries

Researchers have identified a major shift in how to treat brain injuries, after rejuvenating immune cells to support the repair process.

9 Mar 2020

TB bacteria produce fatty acid that triggers a pain-response cough to spread the disease

Tuberculosis is distinguished primarily by the persistent cough that serves to spread the disease. Stopping whatever triggers that cough could greatly reduce the transmission of the disease, which annually kills more than 1.3 million people worldwide.

7 Mar 2020