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Preclinical study shows clear path toward effective treatment for rare bone disease

Researchers at Sanford Burnham Prebys Medical Discovery Institute have led a preclinical study demonstrating that the drug palovarotene suppresses the formation of bony tumors (osteochondromas) in models of multiple hereditary exostoses (MHE).

20 Nov 2017

Trial shows apple allergen as effective treatment option for birch pollen-related apple allergy

The food allergy, which is related to birch pollen, is a very common attendant phenomenon associated with birch pollen allergy - indeed around 70% of those with a birch pollen allergy are also allergic to apples. That amounts to around 280,000 people in Austria.

20 Nov 2017

FDA raids Florida stores that consumers use to buy drugs from Canada

The Food and Drug Administration last month sent criminal investigation agents with search warrants into nine storefronts across Central Florida that help customers order drugs from pharmacies in Canada and overseas at big discounts.

20 Nov 2017

Researchers find way to switch tumor cells between 2D and 3D morphology

Paving the way for testing experimental drugs in more realistic environments, scientists at the National Institute of Standards and Technology have discovered how to make tiny colonies of cells grow in useful new ways inside petri dishes.

17 Nov 2017

Electrochemistry method provides easy access to important classes of compounds

Electrochemistry has undergone a renaissance in recent years and numerous research groups are currently working on the environmentally friendly production or conversion of molecules. However, despite the superiority of electrochemistry, its application to various molecules has been problematic.

17 Nov 2017

Drug used to prevent and treat malaria may also be effective for Zika virus

A new collaborative study led by researchers at Sanford Burnham Prebys Medical Discovery Institute and UC San Diego School of Medicine has found that a medication used to prevent and treat malaria may also be effective for Zika virus.

17 Nov 2017

New model to test effectiveness of existing and potential CF therapies

UNC School of Medicine researchers have developed a new laboratory model of the infection- and inflammation-plagued airways of cystic fibrosis (CF) patients.

17 Nov 2017

Separating side effects could pave way for safe, effective pain medications

Opioid pain relievers can be extremely effective in relieving pain, but can carry a high risk of addiction and ultimately overdose when breathing is suppressed and stops.

16 Nov 2017

New oxytocin chemical sensor could be first step towards early diagnosis of autism

Is it going to be possible to detect features of autism at birth? At the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw a sensor has come into being that means this may become a reality.

16 Nov 2017

FDA approves drug to treat pediatric, adult patients with rare Sly syndrome

The U.S. Food and Drug Administration today approved Mepsevii (vestronidase alfa-vjbk) to treat pediatric and adult patients with an inherited metabolic condition called mucopolysaccharidosis type VII (MPS VII), also known as Sly syndrome. MPS VII is an extremely rare, progressive condition that affects most tissues and organs.

15 Nov 2017

FDA approves first digital pill with sensor - Abilify MyCite

The United States Food and Drugs Administration (FDA), for the first time has approved a digital pill system. The novel pill comes with an in-built sensor that transmits information to a remote location after a person has taken it. Experts believe this is a huge step towards digital medicine and opens new avenues for therapy and diagnostics.

14 Nov 2017

Taking a page from pharma’s playbook to fight the opioid crisis

Dr. Mary Meengs remembers the days, a couple of decades ago, when pharmaceutical salespeople would drop into her family practice in Chicago, eager to catch a moment between patients so they could pitch her a new drug.

14 Nov 2017

FDA approves first drug with digital ingestion tracking system

The U.S. Food and Drug Administration today approved the first drug in the U.S. with a digital ingestion tracking system. Abilify MyCite (aripiprazole tablets with sensor) has an ingestible sensor embedded in the pill that records that the medication was taken.

14 Nov 2017

PCSK9 inhibitor offers clinical benefit to patients with peripheral artery disease

Patients with peripheral artery disease (PAD) are at high risk of heart attack, stroke and cardiovascular death. In addition, PAD patients can suffer major adverse limb events, such as acute limb ischemia - the equivalent of a heart attack in the leg - that can lead to limb loss.

14 Nov 2017

AHA awards California scientist for outstanding achievement in clinical cardiovascular science

The American Heart Association awarded its Clinical Research Prize for 2017 to Robert A. Harrington., M.D., of Stanford University School of Medicine, "for his leadership of research initiatives leading to the development of new anti-thrombotic agents that have dramatically improved everyday medical practice."

13 Nov 2017

Parkinson's disease will soon become looming pandemic, research reveals

New research shows that the number of people with Parkinson's disease will soon grow to pandemic proportions. In a commentary appearing today in the journal JAMA Neurology, University of Rochester Medical Center neurologist Ray Dorsey, M.D. and Bastiaan Bloem, M.D., Ph.D., with Radboud University Medical Center in the Netherlands, argue that the medical community must be mobilized to respond to this impending public health threat.

13 Nov 2017

Scientists invent new way of folding and protecting recombinant proteins

A team from the NUS Yong Loo Lin School of Medicine has invented a fundamentally new way of folding and protecting recombinant proteins.

13 Nov 2017

Researchers find efficient way to produce neurons from pluripotent stem cells

Since their discovery in 2006, induced pluripotent stem cells are a glimmer of hope for many diseases. But further research of the complex regulation of pluripotent stem cell identity revealed unexpected difficulties.

13 Nov 2017

Dengue immunity can provide protection from subsequent Zika infection

Manifestations of Zika virus (ZIKV) infection differ drastically. Sometimes they are catastrophic, most notably when they cause microcephaly in some babies born to infected mothers.

13 Nov 2017

Vaccines in the Aging Population

The World Health Organisation marked World Pneumonia Day on November 12th to promote interventions to protect against, prevent and treat pneumonia. The condition is a worldwide killer affecting people of all ages, however the ‘aging population’ is at an increased risk.

From Pfizer, Inc. 13 Nov 2017