Immune System News and Research

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Women with recurrent miscarriage and infertility are undergoing tests and treatments that have no scientific rationale

Women with recurrent miscarriage and infertility are undergoing tests and treatments that have no scientific rationale and are linked with known risks to mother and fetus, warn researchers in this week's BMJ.

29 Nov 2004

New research may lead to treatments for atherosclerosis

Scientists are one step closer to deciphering the molecular signaling process controlling innate immunity with the discovery that a molecule called IRAK1 regulates the expression of the anti-inflammatory cytokine IL-10. Because atherosclerosis patients often have elevated IL-10 levels, IRAK1 may be a viable target for developing therapeutics for atherosclerosis.

29 Nov 2004

Asthma study looks at genetic variation and influence response to microbial exposure

The "hygiene hypothesis" suggests that exposures to microbes early in life may drive immune system development in a way that reduces a person's susceptibility to asthma and other allergic diseases.

24 Nov 2004

MedImmune and Medarex have announced a collaboration to develop antibodies

MedImmune and Medarex have announced a collaboration to develop antibodies targeting interferon-alpha and the type I interferon receptor 1.

24 Nov 2004

FDA approval of Tysabri, for the treatment of multiple sclerosis

Biogen and Elan Corporation have announced that the U.S. Food and Drug Administration (FDA) has approved Tysabri (natalizumab), as treatment for relapsing forms of multiple sclerosis (MS) to reduce the frequency of clinical relapses.

24 Nov 2004

Gillain-Barre syndrome following influenza vaccination has decreased over the past 12 years

The number of reported cases of Gillain-Barre syndrome (a rare paralytic disorder) that occur following influenza vaccination has decreased over the past 12 years, according to a study in the November 24 issue of JAMA.

24 Nov 2004

Stress quadruples the risk of an asthma attack in children

Stress quadruples the risk of an asthma attack in children, and gives them a double bout of acute symptoms within 48 hours and around six weeks later, finds a small study in Thorax.

24 Nov 2004

Battle of Waterloo could help doctors fight death from multiple organ failure

Waterloo’s battlefield is reigniting the debate about whether modern medicine is always good for you, according to University College London (UCL) scientists who are launching a study of why some critically ill patients recover and others die from multiple organ failure - the number one killer of patients in intensive care.

23 Nov 2004

New research may lead to new treatments for spinal cord injury and multiple sclerosis

For the first time, researchers have used human embryonic stem cells to create new insulating tissue for nerve fibers in a live animal model – a finding that has potentially important implications for treatment of spinal cord injury and multiple sclerosis.

23 Nov 2004

Cells linked to asthma and eczema also help cure deadly illness in mice

Mast cells are immune cells known mostly for their unwanted effects: they cause the wheezing of asthma, the itching of eczema, the sneezing and runny nose of hay fever and, in extreme cases, the life-threatening shock of anaphylaxis.

20 Nov 2004

Scientists have determined the crystal structure of a protein kinase C (PKC) isozyme

This structure should prove extremely useful in the rational design of small molecule inhibitors of PKCÈ, which has been implicated in T-cell mediated disease processes including inflammation and autoimmunity.

19 Nov 2004

Transport route explain why peanuts are one of the most allergenic foods

A UK scientist has discovered the route and type of transport taken by peanut proteins through the gut to the immune system. This route favours an immune response, which helps explain why peanuts are one of the most allergenic foods.

18 Nov 2004

Understanding the signals that delay the spread of follicular lymphoma could provide new therapeutic targets

Scientists at the National Cancer Institute (NCI), have created a model that predicts the survival of follicular lymphoma patients based on the molecular characteristics of their tumors at diagnosis.

18 Nov 2004

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Generic antipsychotic drugs can protect brain cells from a virus that causes a fatal nervous system disorder, according to research conducted at Brown University and Case Western Reserve University.

18 Nov 2004

Early infection in low-birth-weight infants linked with poor neurodevelopmental

Extremely low-birth-weight (ELBW) infants who have an infection during their hospitalization following birth are more likely to have adverse neurodevelopmental outcomes than those infants who do not have an infection, according to a study in the November 17 issue of JAMA.

17 Nov 2004

Researchers find effective treatment for Unusual Fever Syndrome caused by cold exposure

Remember when Grandma used to say, "don’t go out in the cold; you’ll get sick”? It turns out that she was right for a small number of people who have a condition called familial cold autoinflammatory syndrome (FCAS)

16 Nov 2004

Safe, effective and reversible alternative contraceptives for men

Most men know when their family is complete, and vasectomy remains the most effective and safest form of sterilization. Around 10% of vasectomized men in the U.S desire vasectomy reversal due to the high divorce rate in this country and other life circumstances.

16 Nov 2004

Five advanced tests provide answers to couples with unexplained infertility

For couples struggling with infertility, "all routine tests came back negative" are not the words they want to hear. With up to 15% of couples with "unexplained infertility" and another 3% struggling with recurrent pregnancy loss, advanced tests help doctors find answers for their most challenging cases.

16 Nov 2004

Vasogen announces full patient enrollment in its trial of Celacade in peripheral arterial disease

Vasogen today announced that it has reached full enrollment in its 500-patient pivotal phase III SIMPADICO trial of Celacade (immune modulation therapy) for the treatment of peripheral arterial disease (PAD).

16 Nov 2004

Brain inflammation is a sign of autism

A new study by scientists at Johns Hopkins shows that brain inflammation is a sign of autism. The findings are reported in the online edition of Annals of Neurology, the scientific journal of the American Neurological Association.

15 Nov 2004

Immune System News and Research

Women with recurrent miscarriage and infertility are undergoing tests and treatments that have no scientific rationale

New research may lead to treatments for atherosclerosis

Asthma study looks at genetic variation and influence response to microbial exposure

MedImmune and Medarex have announced a collaboration to develop antibodies

FDA approval of Tysabri, for the treatment of multiple sclerosis

Gillain-Barre syndrome following influenza vaccination has decreased over the past 12 years

Stress quadruples the risk of an asthma attack in children

Battle of Waterloo could help doctors fight death from multiple organ failure

New research may lead to new treatments for spinal cord injury and multiple sclerosis

Cells linked to asthma and eczema also help cure deadly illness in mice

Scientists have determined the crystal structure of a protein kinase C (PKC) isozyme

Transport route explain why peanuts are one of the most allergenic foods

Understanding the signals that delay the spread of follicular lymphoma could provide new therapeutic targets

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Early infection in low-birth-weight infants linked with poor neurodevelopmental

Researchers find effective treatment for Unusual Fever Syndrome caused by cold exposure

Safe, effective and reversible alternative contraceptives for men

Five advanced tests provide answers to couples with unexplained infertility

Vasogen announces full patient enrollment in its trial of Celacade in peripheral arterial disease

Brain inflammation is a sign of autism

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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