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Study: 'Open' stem cell chromosomes hold great promise for treating liver, pancreas diseases

Stem cells hold great promise for treating a number of diseases, in part because they have the unique ability to differentiate, specializing into any one of the hundreds of cell types that comprise the human body.

2 Apr 2015

Researchers pinpoint molecular mechanisms that inhibit Hippo pathway in pediatric bone cancers

A particular molecular pathway permits stem cells in pediatric bone cancers to grow rapidly and aggressively, according to researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center.

2 Apr 2015

Novogen appoints PCG Advisory to manage investor-awareness program in the US

Novogen Ltd today announced it has appointed US-based public relations firm, PCG Advisory (PCG), to drive the Company's investor-awareness program in the US. PCG will be using their expertise in creating awareness and establishing key relationships within the US investment community via their targeted outreach campaign.

2 Apr 2015

Astellas Pharma, Medivation announce topline results from enzalutamide Phase 2 STRIVE trial

Astellas Pharma Inc. and Medivation, Inc. today announced topline results from the Phase 2 STRIVE trial comparing enzalutamide with bicalutamide in a study population of men with non-metastatic or metastatic castration-resistant prostate cancer.

2 Apr 2015

Omeros announces commercial availability of Omidria in U.S.

Omeros Corporation, a biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market as well as orphan indications targeting inflammation, coagulopathies and disorders of the central nervous system, announced today the nationwide commercial availability of Omidria (phenylephrine and ketorolac injection) 1%/0.3%.

2 Apr 2015

Scientists develop computer model to predict how liver stores fat

As part of an effort to understand how an experimental drug for atherosclerosis causes the build-up of fat in the liver, scientists have developed a computer model that can predict how the rate at which liver stores fat in response to various situations. Being able to model liver fat storage gives researchers a way to predict the side effects of drugs and environmental factors at much earlier stages in the research and drug development process, possibly reducing the number of experiments involving animal models.

2 Apr 2015

Registration opens for inaugural Stanford Medicine X|ED conference

Registration opened today for the inaugural Stanford Medicine X|ED conference, which will explore the role of technology and networked intelligence in shaping the future of medical education.

2 Apr 2015

LA BioMed scientist awarded $80,000 to study effectiveness of pulmonary rehab in treating COPD

The ATS Foundation and Breathe California of Los Angeles have awarded $80,000 to Harry Rossiter, PhD, a lead researcher at the Los Angeles Biomedical Research Institute, to study the effectiveness of pulmonary rehabilitation in reducing chronic obstructive pulmonary disease (COPD) symptoms in an underserved population in Los Angeles.

2 Apr 2015

Purdue researchers identify new class of chemical insecticides to control mosquitoes

Purdue researchers have identified a new class of chemical insecticides that could provide a safer, more selective means of controlling mosquitoes that transmit key infectious diseases such as dengue, yellow fever and elephantiasis.

2 Apr 2015

Novel molecule inhibits cancer-causing transcription factors

A novel molecule designed by scientists at the University of Massachusetts Medical School and the University of Virginia inhibits progression of a hard-to-treat form of recurring acute myeloid leukemia (AML) in patient tissue.

2 Apr 2015

Old leukemia drug may help in fight against cancer

A drug used for decades to treat leukemia may have other uses in the fight against cancer, researchers at the University of Missouri have found. Previously, doctors used 6-Thioguanine, or 6-TG, as a chemotherapy treatment to kill cancer cells in patients with leukemia.

2 Apr 2015

Long-term effects of using cognitive-enhancing drugs by healthy people need to be determined

The government, pharmaceutical industry, and national medical organisations need to work together to look at the harms and benefits of long-term use of cognitive-enhancing drugs by healthy individuals, say neuroscientists Professor Barbara Sahakian and Dr Sharon Morein-Zamir from the University of Cambridge in the UK, writing in a Personal View in The Lancet Psychiatry journal.

2 Apr 2015

Low doses of imatinib drug can push immune system to combat bacterial infections

Low doses of the anti-cancer drug imatinib can spur the bone marrow to produce more innate immune cells to fight against bacterial infections, Emory researchers have found.

1 Apr 2015

Scientists isolate energy-burning 'beige' fat from adult humans

For the first time, a research team, led by a UC San Francisco biologist, has isolated energy-burning "beige" fat from adult humans, which is known to be able to convert unhealthy white fat into healthy brown fat. The scientists also found new genetic markers of this beige fat.

1 Apr 2015

Intensive therapy needed in paediatric triiodothyronine-predominant Graves' disease

Paediatric patients with triiodothyronine-predominant Graves' disease develop severe disease that needs increased doses of antithyroid drugs, a study shows.

1 Apr 2015

University of York student helps develop new drug release gel

A Chemistry undergraduate at the University of York has helped to develop a new drug release gel, which may help avoid some of the side effects of painkillers such as ibuprofen and naproxen.

1 Apr 2015

Uganda Newborn Study explores ways to improve child mortality rates

In Uganda, child mortality rates are improving, but progress is slower for deaths occurring in the first four weeks of life, or the newborn period, and for stillbirths. But recent evidence from local researchers show that a cost-effective package of care linking families, government-mandated village health teams (a form of community health workers), and health facilities can improve life-saving practices during pregnancy, childbirth and in the first weeks of life; and benefit poorest families the most.

1 Apr 2015

Johns Hopkins researchers find link between premature aging of telomere and lung diseases

Lung diseases like emphysema and pulmonary fibrosis are common among people with malfunctioning telomeres, the “caps” or ends of chromosomes. Now, researchers from Johns Hopkins say they have discovered what goes wrong and why.

1 Apr 2015

Johns Hopkins researchers find link between premature aging of telomere and lung diseases

1 Apr 2015

NIH awards $2.1 million grant to counter antibiotic resistance in Gram-negative bacteria

The National Institutes of Health has awarded Dr. Walter Fast, associate professor of medicinal chemistry at The University of Texas at Austin's College of Pharmacy, a four-year $2.1 million grant to develop small-molecules that counter antibiotic resistance in Gram-negative bacteria. If successful, the research could lead to new drugs for treating bacterial infections that are resistant to most antibiotics.

1 Apr 2015

Drugs News and Research

Study: 'Open' stem cell chromosomes hold great promise for treating liver, pancreas diseases

Researchers pinpoint molecular mechanisms that inhibit Hippo pathway in pediatric bone cancers

Novogen appoints PCG Advisory to manage investor-awareness program in the US

Astellas Pharma, Medivation announce topline results from enzalutamide Phase 2 STRIVE trial

Omeros announces commercial availability of Omidria in U.S.

Scientists develop computer model to predict how liver stores fat

Registration opens for inaugural Stanford Medicine X|ED conference

LA BioMed scientist awarded $80,000 to study effectiveness of pulmonary rehab in treating COPD

Purdue researchers identify new class of chemical insecticides to control mosquitoes

Novel molecule inhibits cancer-causing transcription factors

Old leukemia drug may help in fight against cancer

Long-term effects of using cognitive-enhancing drugs by healthy people need to be determined

Low doses of imatinib drug can push immune system to combat bacterial infections

Scientists isolate energy-burning 'beige' fat from adult humans

Intensive therapy needed in paediatric triiodothyronine-predominant Graves' disease

University of York student helps develop new drug release gel

Uganda Newborn Study explores ways to improve child mortality rates

Johns Hopkins researchers find link between premature aging of telomere and lung diseases

Johns Hopkins researchers find link between premature aging of telomere and lung diseases

NIH awards $2.1 million grant to counter antibiotic resistance in Gram-negative bacteria

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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