Immune System News and Research

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Naturally occurring antifungal agent in saliva kills oral pathogen responsible for most HIV-related oral infections

Oral biologists at the University at Buffalo have shown for the first time how histatin, the naturally occurring antifungal agent in saliva, kills the oral pathogen Candida albicans, the fungus responsible for most HIV-related oral infections.

14 Mar 2005

Discovery may provide a new target to treat sepsis

Part of the immune system's pro-inflammatory response to bacterial invasion is to increase nitric oxide levels with an enzyme called inducible nitric oxide synthase.

14 Mar 2005

New way of looking at MicroRNA and how it controls gene expression

A group of scientists at The Scripps Research Institute is reporting a discovery that sheds light on an area of research fundamental to everything from the normal processes that govern the everyday life of human cells to the aberrant mechanisms that underlie many diseases, including cancer and septic shock.

13 Mar 2005

China trials new HIV vaccine on humans

China which has 840,000 people with HIV, a conservative estimate say experts, will carry out the very first trials of a new virus on human guinea pigs.

13 Mar 2005

Protopic and Elidel may cause cancer

Protopic and Elidel, two treatments for eczema approved in 2000 and 2001, have now been found to cause cancer in three different animal species.

13 Mar 2005

Biologists discover why 10% of Europeans are safe from HIV infection

Scientists have known for some time that these individuals carry a genetic mutation (known as CCR5-Ä32) that prevents the virus from entering the cells of the immune system but have been unable to account for the high levels of the gene in Scandinavia and relatively low levels in areas bordering the Mediterranean.

9 Mar 2005

Computerized order entry systems can increase the risk of medication errors

A new study suggests that computerized order entry systems which are implemented in part to reduce prescribing errors can actually increase the risk of medication errors in certain situations, according to a study in the current issue of JAMA.

9 Mar 2005

Progress toward development of a breast cancer vaccine

Progress toward development of a breast cancer vaccine has been reported by researchers at Washington University School of Medicine and the Siteman Cancer Center in St. Louis.

8 Mar 2005

New system for growing human embryonic stem cells could make therapies utilising the cells safer for patients

A new system for growing human embryonic stem cells could make therapies utilising the cells safer for patients, concludes a study published online by The Lancet (Tuesday, March 8, 2005).

8 Mar 2005

Two chemicals boost immune cells' ability to fight HIV without gene therapy

A UCLA AIDS Institute study has discovered that two chemical compounds may help the immune systems of HIV-infected persons fight the disease without invasive gene therapy.

7 Mar 2005

Thalidomide may have a new lease of life as a cancer treatment

The drug thalidomide may have a new lease of life as a cancer treatment. A small study published in Gut suggests that it slows down the weight loss and wasting associated with advanced disease in patients with pancreatic cancer.

7 Mar 2005

Study looks at the ability of some monkey species to resist developing AIDS

The Tulane National Primate Research Center received a five-year grant of more than $2 million from the National Institute of Allergy and Infectious Diseases to study the ability of some monkey species to resist developing AIDS.

7 Mar 2005

Air Genome Project to sample air using whole genome shotgun sequencing

The J. Craig Venter Institute is launching a pilot project to better understand the diversity of microbes in urban air. In addition to more deeply characterizing the microbes we breathe every day, researchers anticipate that the results will provide information vital to designing systems that detect potentially dangerous biological substances in the air.

7 Mar 2005

WHO says countries should stockpile H5N1 vaccine

The World Health Organization is about to advise countries to stockpile the influenza vaccine strain known as H5N1, responsible for the deadly birdflu outbreak in Southeast Asia.

7 Mar 2005

New therapeutic targets in liver diseases

Many patients with liver diseases often encounter difficulties with therapy and ultimately require liver transplant to survive. Since many acute and chronic liver diseases are driven by immune-mediated mechanisms, there is a necessity to find new therapies that can inhibit these immune-based triggers and block liver damage.

6 Mar 2005

Abnormal brain structure tied to spatial, numerical thinking problems when children lack part of chromosome

Certain genetic diseases affect children's educational abilities in a distinctive pattern: impairing their numerical abilities more than their verbal skills. New research sheds light on this split in abilities by investigating how differences in brain structures may influence how the mind works.

3 Mar 2005

Liquorice - the black stuff we love to eat, may help prevent cancer

Liquorice - the black stuff we love to eat, contains a compound - glycyrrhizic acid which may stop people with a herpes virus from developing cancer.A research team at New York University found the compound - glycyrrhizic acid - possibly has the ability to stop the virus triggering a form of cancer called Kaposi sarcoma.

2 Mar 2005

Molecule from South American tree Quillaja, helps battle disease

The first synthesis of QS-21A, a medicinally important molecule that helps the body battle disease, has been achieved by chemists at the University of Illinois at Urbana-Champaign.

1 Mar 2005

alpha-defensin-1, a protein found in immune cells, can control HIV infection

Theresa Chang and colleagues at Mount Sinai School of Medicine analyzed how alpha-defensin-1 inhibits HIV infection in white blood cells (CD4+ T cells). Defensins have been shown to have anti-HIV activity. The body attempts to protect itself from HIV infection via the innate immune system.

1 Mar 2005

U.S. cancer researchers launch first American-Israeli cancer conference

Leading cancer researchers from Baltimore, Miami and New Jersey have organized the first Joint American-Israeli Conference on Cancer. The meeting, scheduled for March 16 through 18 in Jerusalem, seeks to foster collaboration among physicians and scientists in the two countries.

1 Mar 2005