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HIV-1 and influenza antivirals not effective for treating mild-to-moderate COVID-19 cases

An exploratory randomized, controlled study on the safety and efficacy of either lopinavir/ritonavir (LPV/r) or Arbidol--antivirals that are used in some countries against HIV-1 and to treat influenza , respectively--as treatments for COVID-19, the disease caused by the novel coronavirus SARS-CoV-2, suggests that neither drug improves the clinical outcome of patients hospitalized with mild-to-moderate cases of the disease over supportive care.

20 Apr 2020

Hydroxychloroquine and azithromycin treatment in 80 COVID-19 patients: short-term outcomes

The COVID-19 pandemic is still spreading around the world and affecting nearly 2.4 million people, with over 164,000 dead so far. With neither vaccine nor proven therapeutic drug being available so far, the need of the hour is for effective treatment. Now, a new study reports the potential usefulness of a combination of hydroxychloroquine and azithromycin as a treatment in mild cases of COVID-19 infection and urges the need for further evaluation and widespread use if its findings are confirmed.

19 Apr 2020

Study shows huge effect of obesity on pancreatic cancer development

Pancreatic cancer is expected to become the second-deadliest cancer in the United States by 2030, driven in part by rising obesity rates.

17 Apr 2020

Pregnancy and fetal outcomes with COVID-19

A new study published preprint in the non-peer-reviewed journal medRxiv in April 2020 provides a systematic review of maternal and fetal outcomes in pregnancy affected by COVID-19, as well as the risk of vertical transmission of the virus.

16 Apr 2020

Novel 3D fusion imaging improves diagnosis of coronary artery disease

Coronary artery disease is the most common type of heart disease, according to the Centers for Disease Control and Prevention. About 18.2 million adults in the United States have coronary artery disease.

16 Apr 2020

Analyzing structure of the nipple to understand and fight breast cancer

Nipple-sparing mastectomy is gaining ground as a treatment or preventive measure for breast cancer, given the understandable desire among patients to preserve natural appearance as much as possible.

16 Apr 2020

3D fusion imaging improves coronary artery disease diagnosis

Researchers have overcome limitations of combining CT and MRI with a 3D imaging method for diagnosing coronary artery disease.

16 Apr 2020

Researchers develop a faster, more accurate COVID-19 test

Millions of people have been tested for the novel coronavirus, most using a kit that relies on the polymerase chain reaction.

15 Apr 2020

China with the world: COVID-19 experts dialogues - the 4th talk transcript

Q (Prof. Singer): What do you think about the comorbidities and the age of the patients in the treatment of COVID-19? Is the mortality higher in elderly patients as it is reported from recent papers?

From Mindray 15 Apr 2020

China with the world: COVID-19 experts dialogues - the 2nd talk transcript

Q: Starting from the patient admission to the hospital, what is your rule for ventilation? Do you start from HFNC, CPAP, NIV or go directly to intubation and invasive ventilation when the conventional oxygen therapy fails?

From Mindray 15 Apr 2020

In shutting out threat, seniors in continuing care communities feel shut in

With tight restrictions in place at their continuing care retirement community, Tom and Janice Showler are getting on each other's nerves.

14 Apr 2020

Study shows variability in Medicare coverage for transgender hormone therapies

A new study has shown substantial variability in access to guideline-recommended hormone therapies for older transgender individuals insured through Medicare.

13 Apr 2020

Mayo Clinic highlights the impact of false-negative COVID-19 test results

As COVID-19 testing becomes more widely available, it's vital that health care providers and public health officials understand its limits and the impact false results can have on efforts to curb the pandemic.

9 Apr 2020

New guidance on treating COVID-19 patients with heart attack signs

Much remains unknown about COVID-19, but many studies already have indicated that people with cardiovascular disease are at greater risk of COVID-19.

9 Apr 2020

Chinese newborns experienced mild form of COVID-19

A new paper published by Dr. Zhi-Jiang Zhang and colleagues from Wuhan University in the European Respiratory Journal in April 2020 reports that COVID-19 apparently left little impact on newborns born to infected mothers at the height of the epidemic.

9 Apr 2020

Visualizing 3D microanatomy of human nipple to understand and fight breast cancer

Nipple-sparing mastectomy is gaining ground as a treatment or preventive measure for breast cancer, given the understandable desire among patients to preserve natural appearance as much as possible. But the precise risk of preserving the nipple is not known as the cancer can spread along mammary ducts and to the nipple.

8 Apr 2020

New Fleischner Society statement on chest imaging and management of COVID-19 published

A multinational consensus statement from the Fleischner Society on the role of chest imaging in the management of patients with COVID-19 was jointly published today in the journals Radiology and Chest.

7 Apr 2020

Study highlights a new way to identify antibiotic resistance genes

Apes in U.S. zoos host bacterial communities in their intestinal tracts that are more similar to those of people who eat a non-Western diet than to the gut makeup of their wild ape cousins, according to a new study from Washington University in St. Louis.

7 Apr 2020

Immunosuppressant shows promise in addressing COVID-19 symptoms for patients with blood cancers

A case study of a patient in Wuhan, China, suggests that the immunosuppressant tocilizumab may be an effective COVID-19 treatment for very ill patients who also have multiple myeloma and other blood cancers.

5 Apr 2020

Researchers identify the most common characteristics of fatal COVID-19 cases

In a new study, researchers identified the most common characteristics of 85 COVID-19 patients who died in Wuhan, China in the early stages of the coronavirus pandemic.

3 Apr 2020