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Diet based on UK health guidelines could reduce CVD risk

Men and women who adapt their daily diet to meet current UK dietary guidelines could reduce their risk of a heart attack or a stroke by up to a third, according to a new study by King's College London.

18 Mar 2015

Selten Pharma's SPI-026 granted FDA Orphan Drug Designation for treatment of PAH

Selten Pharma, Inc., a privatively held biopharmaceutical company focused on the development and commercialization of therapies for the treatment of rare diseases, announced today that its lead compound tacrolimus (SPI-026) has been granted Orphan Drug Designation by the U.S. Food & Drug Administration for the treatment of pulmonary arterial hypertension (PAH).

18 Mar 2015

Genetic markers may help decide who benefits from aspirin, NSAIDs in lowering risk of colorectal cancer

An Indiana University cancer researcher and her colleagues have identified genetic markers that may help determine who benefits from regular use of aspirin and other nonsteroidal anti-inflammatory drugs for lowering one's risk of developing colorectal cancer.

18 Mar 2015

Finding could improve global efforts to prevent HIV transmission, save lives

People who recently have been infected with HIV may not be as highly infectious as previously believed, a finding that could improve global efforts to prevent HIV transmission and save lives. In particular, the finding bolsters the strategy of treating patients with antiretroviral drugs before the onset of AIDS to prevent transmission.

18 Mar 2015

Researchers discover new metabolic mechanisms linked to macrophage polarization

A group of researchers from Washington University in St. Louis, Agios Pharmaceuticals and ITMO University has discovered new metabolic mechanisms that regulate macrophage polarization - the unique ability of these immune cells to change their specialization depending on the required task.

18 Mar 2015

Researchers reveal how omega-3 fatty acids inhibit growth of prostate cancer cells

Washington State University researchers have found a mechanism by which omega-3 fatty acids inhibit the growth and spread of prostate cancer cells. The findings, which are at odds with a 2013 study asserting that omega-3s increase the risk of prostate cancer, point the way to more effective anti-cancer drugs.

18 Mar 2015

Gentronix signs three-year technology access deal with SIMM

UK based Gentronix Limited, the specialist genetic toxicology company, today announced it has signed a three year technology access deal with one of China's most prestigious research intensive institutes, Shanghai Institute Materia Medica, Chinese Academy of Sciences.

18 Mar 2015

Young children, teens at risk for unintentional medicine poisoning

Nearly half of the 1.34 million calls to poison centers for children each year are related to medicine. In fact, every day, there are more than 1,100 calls about a young child getting into medicine or getting too much medicine.

18 Mar 2015

Pharmalink AB acquires anti-inflammatory drug candidate from Synartro AB

Pharmalink AB, a specialty pharma company, announces that it has acquired a novel product candidate in development for treating inflammation from Synartro AB. No financial details are disclosed.

18 Mar 2015

NCCN panelists discuss on evidence-based decision-making at bedside

On Friday, March 13, 2015, as part of its 20th Annual Conference: Advancing the Standard of Cancer Care, the National Comprehensive Cancer Network hosted its second roundtable, Value-Based Decision-Making at the Bedside, which reflected on the tools available to oncology clinicians, such as clinical practice guidelines and pathways, and how the use of these tools has impacted bedside evidence-based decision-making for both physicians and patients, the criteria used to assess shared decision-making, and the relationship between outcomes and cost when determining value.

18 Mar 2015

Students attending Brainworks program to learn how regular exercise may help improve brain health

About 140 seventh- and eighth-graders attending Cedars-Sinai's Brainworks program March 23 will learn how hopping, skipping, jumping and other elements of a regular exercise routine may help improve brain health. An exercise station - a new feature of the 17-year-old program - will be one of nine areas where students will interact with Cedars-Sinai neurosurgeons, neurologists, neuroscientists and other health professionals.

18 Mar 2015

Scientists identify how mRNA deciphers critical information within genetic code

Case Western Reserve scientists have discovered that speed matters when it comes to how messenger RNA (mRNA) deciphers critical information within the genetic code — the complex chain of instructions critical to sustaining life. The investigators' findings, which appear in the March 12 journal Cell, give scientists critical new information in determining how best to engage cells to treat illness — and, ultimately, keep them from emerging in the first place.

18 Mar 2015

Physicians, researchers to discuss advances in cancer immunotherapies at UChicago symposium

The Ben May Department for Cancer Research at the University of Chicago will hold a day-long symposium on cancer immunotherapy for physicians and researchers.

18 Mar 2015

New study finds that prices of leading cancer drugs increased by 10% annually since 1995

The prices of leading cancer drugs have risen at rates far outstripping inflation over the last two decades, according to a new study co-authored by an MIT economist -- but the exact reasons for the cost increases are unclear.

18 Mar 2015

Sildenafil drug may effectively relieve nerve damage in men with long-term diabetes

New animal studies at Henry Ford Hospital found that sildenafil, a drug commonly used to treat erectile dysfunction, may be effective in relieving painful and potentially life-threatening nerve damage in men with long-term diabetes.

18 Mar 2015

Simultaneous use of hormones and statins can protect women from heart disease after menopause

Hormones may not protect women from heart disease or stroke after menopause, but when combined with cholesterol-lowering statin drugs, they may help protect women from these killers, shows a population study from Sweden to be published in the April issue of Menopause, the journal of The North American Menopause Society.

18 Mar 2015

Anesthetics interfere with certain proteins in excitatory neurons that transmit signals

Anesthetics have been used in surgical procedures for more than 150 years, but the mechanisms by which inhaled anesthesia actually work are poorly understood. Now, researchers at Johns Hopkins Medicine have discovered that anesthetics bind to and interfere with certain proteins in excitatory neurons, which are necessary for these neurons to transmit signals involved in anesthesia and the perception of pain.

18 Mar 2015

International researchers reveal significance of water for functional protein dynamics

An international team of researchers from the CEA, the CNRS, the Institut Laue-Langevin, the Jülich Centre for Neutron Science, the University of California Irvine, the Australian Institute of Science and Technology Organisation, the Max Planck Institute Mülheim and the University of Perugia has shed light on the molecular mechanism behind the importance of water for functional protein dynamics.

18 Mar 2015

New drug fails to prevent irreversible injury to the heart after angioplasty

Patients who received the new drug Bendavia before undergoing angioplasty or receiving a stent to clear blocked arteries after a heart attack showed no significant reduction in scarring as compared to patients given a placebo, according to a study presented at the American College of Cardiology's 64th Annual Scientific Session.

18 Mar 2015

Global breast cancer therapeutics market estimated to reach $13.38 billion in 2018

Despite the availability of approximately 25 drugs for the treatment of breast cancer, the unmet need in the global market is vast. To address this drawback, pharmaceutical companies have established a robust pipeline that currently has about 52 drugs in development. While chemotherapy remains the most important class of drugs for breast cancer treatment, the trend toward targeted drugs is on the rise.

17 Mar 2015

Drugs News and Research

Diet based on UK health guidelines could reduce CVD risk

Selten Pharma's SPI-026 granted FDA Orphan Drug Designation for treatment of PAH

Genetic markers may help decide who benefits from aspirin, NSAIDs in lowering risk of colorectal cancer

Finding could improve global efforts to prevent HIV transmission, save lives

Researchers discover new metabolic mechanisms linked to macrophage polarization

Researchers reveal how omega-3 fatty acids inhibit growth of prostate cancer cells

Gentronix signs three-year technology access deal with SIMM

Young children, teens at risk for unintentional medicine poisoning

Pharmalink AB acquires anti-inflammatory drug candidate from Synartro AB

NCCN panelists discuss on evidence-based decision-making at bedside

Students attending Brainworks program to learn how regular exercise may help improve brain health

Scientists identify how mRNA deciphers critical information within genetic code

Physicians, researchers to discuss advances in cancer immunotherapies at UChicago symposium

New study finds that prices of leading cancer drugs increased by 10% annually since 1995

Sildenafil drug may effectively relieve nerve damage in men with long-term diabetes

Simultaneous use of hormones and statins can protect women from heart disease after menopause

Anesthetics interfere with certain proteins in excitatory neurons that transmit signals

International researchers reveal significance of water for functional protein dynamics

New drug fails to prevent irreversible injury to the heart after angioplasty

Global breast cancer therapeutics market estimated to reach $13.38 billion in 2018

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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