Animal Model News and Research

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Ocular melanoma - potential new treatment options

Ocular melanoma is rarely detected before it has grown large enough to impair vision or to metastasize.

20 Feb 2008

Transplanted cells can cure hemophilia

Scientists at the Albert Einstein College of Medicine of Yeshiva University have shown for the first time that transplanted cells can cure hemophilia A (the most common form of the disease) in an animal model.

18 Feb 2008

Two-way cell talk provides clues about neuromuscular disease

It's a scientific given that neurons tell other cells what to do, but new evidence suggests that, like with any good relationship, these target cells also have much to contribute, scientists say.

17 Feb 2008

Researchers use embryonic stem cells to develop functioning immune system blood cells

For the first time, researchers have used embryonic stem cells to develop functioning immune system blood cells -- an important step in eventually using embryonic stem cells as an alternative source of cells for traditional bone marrow transplantations.

14 Feb 2008

Some cases of autism may be traced to the immune system of mothers during pregnancy

New research from the UC Davis M.I.N.D. Institute and Center for Children's Environmental Health has found that antibodies in the blood of mothers of children with autism bind to fetal brain cells, potentially interrupting healthy brain development.

12 Feb 2008

Advances in age-related macular degeneration treatment

A new study of age-related macular degeneration (AMD), a disease that affects more than nine million Americans, will pave the way for the biopharmaceutical industry to develop better treatments and cures, according to the Foundation Fighting Blindness, which partially funded the research.

4 Feb 2008

Carbon monoxide causes direct damage to the heart muscle

Lack of oxygen isn't the only way that carbon monoxide (CO) damages the heart, say researchers at Rhode Island Hospital.

30 Jan 2008

Stem-cell transplantation improves muscles in MD animal model

Using embryonic stem cells from mice, UT Southwestern Medical Center researchers have prompted the growth of healthy - and more importantly, functioning - muscle cells in mice afflicted with a human model of Duchenne muscular dystrophy.

21 Jan 2008

Smallest particles from vehicle emissions may promote hardening of the arteries

Patients prone to heart disease may one day be told by physicians to avoid not only fatty foods and smoking but air pollution too.

18 Jan 2008

An emerging candidate for protecting patients from liver injury after abdomen surgery

Many patients worldwide are going to receive major abdomen surgery or intestine transplantation every year and expect to be afflicted with liver injury afterwards.

17 Jan 2008

Mouse model shows potential efficacy of HIV prevention strategy

A new kind of laboratory mouse can be used to test the efficacy of much-needed methods to prevent transmission of HIV, the virus that causes AIDS, according to research by J. Victor Garcia and colleagues at the University of Texas Southwestern Medical Center in Dallas.

15 Jan 2008

Trichloroethylene exposure linked to Parkinsonism

Industrial workers who worked with trichloroethylene (TCE) may face a greater risk for parkinsonism, a study by a team of University of Kentucky researchers shows.

10 Jan 2008

Peptide hormone found in the body prevents obesity and diabetes

A new study finds that a chemical found in the body is capable of promoting weight loss, improving insulin resistance and reversing diabetes in an animal model.

4 Jan 2008

Daily alcohol use causes changes in sexual behavior

A team of researchers at Penn Sate has used an animal model to reveal, for the first time, a physiological basis for the effect of alcohol on male sexual behavior, including increased sexual arousal and decreased sexual inhibition.

4 Jan 2008

New drug targets may fight tuberculosis and other bacterial infections in novel way

Over the course of the 20th Century, doctors waged war against infectious bacterial illness with the best new weapon they had: antibiotics.

28 Dec 2007

Cardiac stem cell therapy research

Since the year 2000, much has been learned about the potential for using transplanted cells in therapeutic efforts to treat varieties of cardiac disorders.

28 Dec 2007

Paradigm shift in TB: virulence factors, not antibiotics

Over the course of the 20th Century, doctors waged war against infectious bacterial illness with the best new weapon they had: antibiotics.

27 Dec 2007

Researchers prevent muscle weakness caused by myasthenia gravis

Severe muscle weakness caused by myasthenia gravis - a highly debilitating autoimmune disorder - can be prevented or reversed by blocking a key step in the immune response that brings on the disease, researchers at the Saint Louis University School of Medicine have found.

20 Dec 2007

The blood-brain barrier: A misunderstood key to finding life-saving cures to brain disease

An international team of scientists that includes a Saint Louis University researcher suggest several strategies to propel research for treatments of brain diseases that include multiple sclerosis, Alzheimer's disease, obesity and stroke in the January issue of the Lancet Neurology.

20 Dec 2007