Clinical Trial News and Research

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Combining health data with whole genome sequence data in cancer patients can help doctors provide more tailored care

Researchers evaluated the impact of integrating whole-genome sequencing data with clinical outcomes across 13,880 tumors from 33 cancer types, assessing precision care potentials within the UK NHS through the 100,000 Genomes Cancer Programme.

16 Jan 2024

Paxlovid treatment in 20% of COVID-19 patients could avert 850,000 hospitalizations, save up to $170 billion

A study in the Emerging Infectious Diseases journal shows treating 20% of COVID-19 patients with Paxlovid could save up to 0.85 million lives and reduce the economic burden by US $170.17 billion in the US.

14 Jan 2024

Planning prompts show promise in improving prescribing safety

Physicians who are notified that a patient has died of a drug overdose are more judicious in issuing controlled substances if the notification includes a plan for what to do during subsequent patient visits, according to a study published today in Nature Communications.

13 Jan 2024

New study offers hope for reducing malaria in pregnant women living with HIV

In women living with HIV, preventive treatment with DHA-PPQ is a safe and effective strategy to prevent malaria during pregnancy, according to the final results of MAMAH, a clinical trial funded by the European & Developing Countries Clinical Trials Partnership (EDCTP) and coordinated by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation.

12 Jan 2024

FDA-approved drug may help to decrease pain after surgery, study finds

Researchers in the Department of Anesthesia and Perioperative Medicine at the Medical University of South Carolina (MUSC) have found that an FDA-approved drug may help to decrease pain after surgery.

12 Jan 2024

Urinary incontinence associated with higher odds of future disability

If you are one of the 30% to 50% of women experiencing urinary incontinence, new research suggests that it could turn into a bigger health issue.

12 Jan 2024

Drinkable, carbon monoxide-infused foam supercharges cancer therapy

Did smokers do better than non-smokers in a clinical trial for an experimental cancer treatment? That was the intriguing question that led University of Iowa researchers and their colleagues to develop a drinkable, carbon monoxide-infused foam that boosted the effectiveness of the therapy, known as autophagy inhibition, in mice and human cells.

12 Jan 2024

UK's maternal mortality rate hits 20-year high

The latest set of data presented by the MBRRACE-UK Collaboration investigation into maternal deaths in the UK shows that the mortality rate for women who died during or soon after pregnancy has increased to levels not seen since 2003-05.

11 Jan 2024

University of Oxford launches first-in-human trial of the ChAdOx1 NipahB vaccine

The University of Oxford has launched a new clinical trial to test a vaccine to protect people against deadly Nipah virus.

11 Jan 2024

Extended liver preservation technique shows promise for daytime transplants

Phase II clinical trial evaluates the safety and feasibility of prolonged DHOPE for extending human donor liver preservation to 20 hours, showing potential for facilitating daytime liver transplantation.

11 Jan 2024

Glioblastoma tumor cells mimic neurons to evade treatment

Certain cancers are more difficult to treat because they contain cells that are highly skilled at evading drugs or our immune systems by disguising themselves as healthy cells.

11 Jan 2024

Study: Low-dose calcium equally effective as high-dose in preventing preeclampsia

To help prevent preeclampsia and preterm birth - common complications in pregnancy that can be fatal to women and newborns - low-dose calcium supplementation (equivalent to one 500-milligram pill per day) may be as effective as the World Health Organization (WHO)'s recommended high-dose calcium supplementation (equivalent to three 500-milligram pills taken throughout each day), according to a new study led by Harvard T.H. Chan School of Public Health and collaborators in India and Tanzania.

10 Jan 2024

Carvedilol improves heart health marker in childhood cancer survivors

Physicians at City of Hope, one of the largest cancer research and treatment organizations in the United States, in cooperation with the Children's Oncology Group (COG), have conducted the largest clinical trial to date seeking to reduce the risk of people who have survived childhood cancer from developing heart failure.

9 Jan 2024

Smartphone app offers relief for debilitating tinnitus

An international research team has shown that the debilitating impact of tinnitus can be effectively reduced in just weeks by a training course and sound therapy delivered via a smartphone app.

9 Jan 2024

CRISPR cures on the horizon: Breakthrough center aims to heal rare, deadly genetic diseases

Children and adults with rare, deadly genetic diseases have fresh hope for curative therapies, thanks to a new collaboration between the Innovative Genomics Institute (IGI) and Danaher Corporation, a global life sciences and diagnostics innovator.

9 Jan 2024

Children with neuroblastomas may benefit from new drug cocktail

Children who develop neuroblastomas, a rare form of cancer which develops in nerve cells, may benefit from receiving certain anti-tumor drugs as well as chemotherapy, a new trial has found.

9 Jan 2024

Ginseng's hidden gems: Rare ginsenosides emerge as potent players in the future of medicine

Review in the Journal of Advanced Research summarizes the properties, applications, and production of rare ginsenosides (RGs), highlighting their potential in treating various diseases including cancer and cardiovascular ailments.

8 Jan 2024

Measuring airborne grass allergen levels could be key to controlling hay fever symptoms

Measuring airborne grass allergen levels instead of pollen counts will be more beneficial for hay fever sufferers as new research shows grass allergen levels are more consistently associated with hay fever symptoms than grass pollen counts.

8 Jan 2024

AI-enabled digital stethoscope could improve the diagnosis of peripartum cardiomyopathy

New research from Mayo Clinic suggests that artificial intelligence (AI) could improve the diagnosis of peripartum cardiomyopathy, a potentially life-threatening and treatable condition that weakens the heart muscle of women during pregnancy or in the months after giving birth.

8 Jan 2024

Combining immunotherapy and radiation to tackle aggressive triple-negative breast cancer

Cedars-Sinai Cancer investigators have analyzed the cells within triple-negative breast cancer tumors before and after radiation therapy with immunotherapy, identifying three patient groups with different responses to the treatment.

8 Jan 2024

Clinical Trial News and Research

Combining health data with whole genome sequence data in cancer patients can help doctors provide more tailored care

Paxlovid treatment in 20% of COVID-19 patients could avert 850,000 hospitalizations, save up to $170 billion

Planning prompts show promise in improving prescribing safety

New study offers hope for reducing malaria in pregnant women living with HIV

FDA-approved drug may help to decrease pain after surgery, study finds

Urinary incontinence associated with higher odds of future disability

Drinkable, carbon monoxide-infused foam supercharges cancer therapy

UK's maternal mortality rate hits 20-year high

University of Oxford launches first-in-human trial of the ChAdOx1 NipahB vaccine

Extended liver preservation technique shows promise for daytime transplants

Glioblastoma tumor cells mimic neurons to evade treatment

Study: Low-dose calcium equally effective as high-dose in preventing preeclampsia

Carvedilol improves heart health marker in childhood cancer survivors

Smartphone app offers relief for debilitating tinnitus

CRISPR cures on the horizon: Breakthrough center aims to heal rare, deadly genetic diseases

Children with neuroblastomas may benefit from new drug cocktail

Ginseng's hidden gems: Rare ginsenosides emerge as potent players in the future of medicine

Measuring airborne grass allergen levels could be key to controlling hay fever symptoms

AI-enabled digital stethoscope could improve the diagnosis of peripartum cardiomyopathy

Combining immunotherapy and radiation to tackle aggressive triple-negative breast cancer

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