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Scientists hypothesize SARS-CoV-2 cryptically circulating among humans before the current outbreak

As nations begin to recover, researchers from the National Taiwan University and Academia Sinica in Taipei have been looking to identify the changes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) underwent over the course of the pandemic in order to better understand why the disease showed such virulence.

20 Sep 2021

Early treatment with ACE inhibitors improves cardiac outcomes of patients with Becker muscular dystrophy

There is no consensus on when to introduce cardioprotective treatment in patients with Becker muscular dystrophy (BMD), and practice varies widely.

20 Sep 2021

Role of host gene variants in COVID-19 severity

A new study discusses the importance of common, rare, and intermediate variants of several host genes to the clinical severity of infection with SARS-CoV-2.

20 Sep 2021

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

Researchers from the University of Southern California investigated mutations in the N-terminal and RBD domains of the spike protein.

20 Sep 2021

Characterizing the flexibility of SARS-CoV-2 variant of concern spike proteins

A novel protein modeling method assesses changes to the conformation of the SARS-CoV-2 spike protein that have been encountered by mutation.

19 Sep 2021

Analysis of 2021 Ebola outbreak reveals long-term dormant infections

Guinea recently experienced its second outbreak of the Ebola virus disease within the last decade.

19 Sep 2021

A variant analysis approach for SARS-CoV-2 in wastewater samples

A recent study proposes a simple and specific method for the enhanced detection of the SARS-CoV-2 VOCs in wastewater samples.

19 Sep 2021

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

In a recent study, Swiss researchers use improved techniques to understand the biological significance behind the Delta variant.

19 Sep 2021

Pairing bacteriophages with antibiotics to fight drug-resistant pathogens

Mycobacterium abscessus, a relative of the bacteria that cause tuberculosis and leprosy, is responsible for particularly severe damage to human lungs and can be resistant to many standard antibiotics, making infections extremely challenging to treat.

18 Sep 2021

Research reveals a possible new treatment approach for pediatric rhabdomyosarcoma

Scientists at St. Jude Children's Research Hospital have revealed how the tumor suppressor gene PTEN plays a more important role in pediatric rhabdomyosarcoma than was previously appreciated.

18 Sep 2021

New discovery elucidates the link between inflammation and pancreatic cancer development

A new discovery from researchers at The University of Texas MD Anderson Cancer Center has clarified the long-established connection between inflammation and pancreatic cancer development.

16 Sep 2021

Study looks at drug resistance in BRAF-mutated gliomas

Looking to understand why some brain tumors with a specific mutation can start to reject drugs commonly used to treat them, CU Cancer Center member Jean Mulcahy Levy, MD, led researchers from institutions around the country - including several from the University of Colorado School of Medicine - to study samples of brain tumors before and after being treated with the drug.

16 Sep 2021

Therapeutic potential of clinical-grade ACE2 for blocking SARS-CoV-2 variants

According to new research by an international team of scientists, all SARS-CoV-2 variants, including variants of concern (VOC) Alpha, Beta, Gamma, and Delta, exhibit enhanced affinity toward recombinant human soluble ACE2.

16 Sep 2021

Evolved SARS-CoV-2 viruses gain higher infectivity and cause more rapid infection spread

Viruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strains that show attenuated virulence. Such strains may act as vaccines if the attenuated virus can produce immunity without serious disease.

16 Sep 2021

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Researchers from The University of Texas MD Anderson Cancer Center have discovered that grouping epidermal growth factor receptor (EGFR) mutations by structure and function provide an accurate framework to match patients with non-small cell lung cancer (NSCLC) to the right drugs.

16 Sep 2021

Study looks at exposure to different SARS-CoV-2 variants and immune response

Researchers compared the responses against several SARS-CoV-2 VoCs in sera from individuals exposed to variant infection, vaccination, or both.

15 Sep 2021

Single protein is a key player in two very common forms of dementia, study reveals

Dementia has many faces, and because of the wide range of ways in which it can develop and affect patients, it can be very challenging to treat.

15 Sep 2021

SARS-CoV-2 variants show substantial differences in spike structure

To investigate the impact of these mutations, researchers performed cryo-electron microscopy analysis on the variants spike proteins to determine any structural changes.

15 Sep 2021

New automated approach to detecting SARS-CoV-2 variants with increased growth rates

Researchers in the United States have developed a new automated approach to detecting variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – that have increased growth rates over other lineages.

15 Sep 2021

Study reveals role of globalization and zoonosis in the emergence and spread of SARS-CoV-2 variants

A recent study aimed to use their own classification of different SARS-CoV-2 lineages that would help monitor their genetic features and geographical origins.

14 Sep 2021

Mutation News and Research

Scientists hypothesize SARS-CoV-2 cryptically circulating among humans before the current outbreak

Early treatment with ACE inhibitors improves cardiac outcomes of patients with Becker muscular dystrophy

Role of host gene variants in COVID-19 severity

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

Characterizing the flexibility of SARS-CoV-2 variant of concern spike proteins

Analysis of 2021 Ebola outbreak reveals long-term dormant infections

A variant analysis approach for SARS-CoV-2 in wastewater samples

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

Pairing bacteriophages with antibiotics to fight drug-resistant pathogens

Research reveals a possible new treatment approach for pediatric rhabdomyosarcoma

New discovery elucidates the link between inflammation and pancreatic cancer development

Study looks at drug resistance in BRAF-mutated gliomas

Therapeutic potential of clinical-grade ACE2 for blocking SARS-CoV-2 variants

Evolved SARS-CoV-2 viruses gain higher infectivity and cause more rapid infection spread

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Study looks at exposure to different SARS-CoV-2 variants and immune response

Single protein is a key player in two very common forms of dementia, study reveals

SARS-CoV-2 variants show substantial differences in spike structure

New automated approach to detecting SARS-CoV-2 variants with increased growth rates

Study reveals role of globalization and zoonosis in the emergence and spread of SARS-CoV-2 variants

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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