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Study sheds light on role of antibodies in vaccine protection against COVID-19 variants

Efforts to contain the Covid-19 pandemic have largely focused on vaccine development and deployment. But how exactly do our immune systems respond to COVID-19 vaccines?

13 Nov 2023

Exploring the use of psychedelics as novel treatments for psychiatric disorders

Psychedelic compounds such as psilocybin, a substance found in various mushroom species, are garnering more research support as novel treatments for psychiatric disorders, but questions remain concerning who they may help the most.

13 Nov 2023

Pioneering study finds predictive biomarker in lung adenocarcinoma

The potential of the transcriptome of tumor-adjacent normal lung tissue in predicting the prognosis of lung cancer.

13 Nov 2023

Changing environment can have long-term, significant effects on the brain

Changes in a person's environment can have long-term, significant effects on the brain, whether it's the inhalation of wildfire smoke or the experience of childhood trauma.

13 Nov 2023

SELECT trial: Semaglutide reduces cardiovascular events by 20% in overweight or obese patients without diabetes

Findings from a multi-center, international clinical trial reported by a Cleveland Clinic physician show that semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease who do not have diabetes.

13 Nov 2023

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

13 Nov 2023

Australian study shows combined genomic screening for major hereditary diseases is cost-effective and health-saving

In an Australian study published in EClinicalMedicine, researchers evaluated the impact of a combined genomic screening program for hereditary breast and ovarian cancer, Lynch syndrome, and familial hypercholesterolemia in young adults. The program proved to be cost-effective, reducing healthcare costs and averting numerous health events, while emphasizing the need for further optimization and equitable access within public healthcare systems.

12 Nov 2023

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

Researchers reveal mechanism by which MAF protein increases metastasis risk in breast cancer patients

Breast cancer is the most common form of cancer among women, with more than 2 million new cases diagnosed each year. In cases where the tumour remains localised in the breast, survival rates are remarkably high, at around 90%.

9 Nov 2023

New hope for preventing preterm births: IL-6R blockade reduces neonatal mortality

The role of interleukin (IL)-6 and IL-1α in sterile intraamniotic inflammation (SIAI), a condition associated with preterm birth (PTB).

9 Nov 2023

Study links lower testosterone levels with increased arthritis risk

The relationship between serological testosterone levels and arthritis among United States (US) adults.

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Cannabis and derivatives show promise in reducing weight and waist circumference, with nuanced effects on body fat

The study in the International Journal of Obesity reports that cannabis and its derivatives may influence weight and waist circumference, with different effects on body fat, suggesting potential as a therapeutic aid in obesity management.

8 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

Patients with advanced HER2-positive breast cancer live longer if treated with pyrotinib, trial shows

Patients with HER2-positive breast cancer that has started to spread to other parts of the body survive for longer if they are treated with a new drug called pyrotinib, according to results from the longest follow-up of the PHOEBE randomized clinical trial in China.

8 Nov 2023

Study compares the immunogenicity and safety of two SARS-CoV-2 vaccines

The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019. Since then, extensive efforts have been made to develop and evaluate vaccines to combat the virus.

8 Nov 2023

Gamma delta T cells engineered to be more potent and long-lasting against cancer

UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for "off-the-shelf" cell therapy to treat challenging cancers.

8 Nov 2023

Pharmacogenomics holds promise for personalized dementia therapies

Pharmacogenomics-based studies in the research for personalized therapeutics for dementia

8 Nov 2023

Immune imprinting: The crux of waning COVID-19 booster effectiveness against new variants

The study in Nature Microbiology reviews the concept of immune imprinting and its influence on antibody responses to SARS-CoV-2, highlighting challenges for COVID-19 booster vaccination efficacy against emerging variants. Researchers suggest that understanding immune imprinting is crucial for developing vaccines that elicit broad and lasting immune protection.

7 Nov 2023

CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

New research at ACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus while maintaining a robust response to vaccines.

7 Nov 2023

Receptor News and Research

Study sheds light on role of antibodies in vaccine protection against COVID-19 variants

Exploring the use of psychedelics as novel treatments for psychiatric disorders

Pioneering study finds predictive biomarker in lung adenocarcinoma

Changing environment can have long-term, significant effects on the brain

SELECT trial: Semaglutide reduces cardiovascular events by 20% in overweight or obese patients without diabetes

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

Australian study shows combined genomic screening for major hereditary diseases is cost-effective and health-saving

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Researchers reveal mechanism by which MAF protein increases metastasis risk in breast cancer patients

New hope for preventing preterm births: IL-6R blockade reduces neonatal mortality

Study links lower testosterone levels with increased arthritis risk

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Cannabis and derivatives show promise in reducing weight and waist circumference, with nuanced effects on body fat

Cannabis use alters DNA methylation, with implications beyond smoking effects

Patients with advanced HER2-positive breast cancer live longer if treated with pyrotinib, trial shows

Study compares the immunogenicity and safety of two SARS-CoV-2 vaccines

Gamma delta T cells engineered to be more potent and long-lasting against cancer

Pharmacogenomics holds promise for personalized dementia therapies

Immune imprinting: The crux of waning COVID-19 booster effectiveness against new variants

CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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