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Study: Certain prostate cancer medications linked to cardiac death risk

A new study has found that certain prostate cancer medications are linked with an increased risk of dying from heart-related causes in men with congestive heart failure or prior heart attacks. Published in BJU International, the findings will help doctors and patients weigh the benefits and risks of the drugs.

30 Oct 2014

New standard of care for pediatric AML patients who receive umbilical cord transplants

A new standard of care for children facing acute myeloid leukemia (AML) may be clear, following a multi-year study published in the latest edition of the New England Journal of Medicine.

30 Oct 2014

UCSD researchers develop novel ultrasound technology to diagnose two heart conditions

Engineers at the University of California, San Diego have determined for the first time the impact of a ring-shaped vortex on transporting blood flow in normal and abnormal ventricles within the human heart. They worked with cardiologists at the Non-Invasive Cardiology Laboratory at Gregorio Marañon Hospital, in Madrid, Spain.

29 Oct 2014

Mayo Clinic orthopedic surgeon explains how scoliosis affects Baby Boomers

For many adults, the word scoliosis conjures up childhood memories of lining up in gym class for an examination by the school nurse. But scoliosis isn't just a pediatric condition. Curvature of the spine can develop in adults too, and the osteoporosis that can accompany menopause is a risk factor.

29 Oct 2014

Rapamycin and dasatinib combination may be beneficial in treating breast cancer, say scientists

The uncontrolled growth of cancer cells arises from their ability to hijack the cell’s normal growth program and checkpoints. Usually after therapy, a second cancer-signaling pathway will open after the primary one shuts down — creating an ingenious escape route for the cancer cell to survive. The answer, say Case Western Reserve researchers, is to anticipate and block that back-up track by prescribing two drugs from the start.

29 Oct 2014

Royal Holloway-led researchers to develop novel spinal cord injury treatment

Dr Rafael Yáñez-Muñoz, from the School of Biological Sciences at Royal Holloway, University of London, is leading a team of researchers working to develop a novel treatment for spinal cord injury - which leaves sufferers with devastating, life-long effects including paralysis.

29 Oct 2014

New data demonstrates improved outcomes in psoriasis patients treated with Daivobet gel

Interim results from one of the largest and longest clinical trials ever conducted for a topical treatment in psoriasis showed that after eight weeks of treatment with calcipotriol/betamethasone dipropionate (Daivobet gel), the treatment was highly efficacious, preferred by patients and improved patients' and the physicians’ assessments of disease severity.

29 Oct 2014

Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

The classic description of game theory was described by the prisoner's dilemma, which is a situation in which two players have two options where the outcome depends on the simultaneous choice made by the other.

29 Oct 2014

Generic aromatase inhibitors increase breast cancer treatment adherence by 50%

Although oral hormonal therapy is known to substantially reduce breast cancer recurrence in women with hormone receptor-positive tumors, about one-half of patients fail to take their medications as directed. A new study by Columbia University Medical Center researchers has found that the introduction of generic aromatase inhibitors (the most common type of hormone therapy), which are considerably less expensive than their brand name counterparts, increased treatment adherence by 50 percent.

28 Oct 2014

Pre-treatment pain intensity predicts survival of patients with head and neck cancer

Pre-treatment pain intensity is an independent survival predictor for patients with head and neck cancer, according to new research published in The Journal of Pain, the peer-reviewed publication of the American Pain Society.

28 Oct 2014

Study: Obese youths with ALL have worse outcomes than lean counterparts

Obese youths with acute lymphoblastic leukemia (ALL) are known to have worse outcomes than their lean counterparts. To find out why, investigators at Children's Hospital Los Angeles studied patients who were obese at the time of their diagnosis with ALL to determine if body mass index (BMI) impacted response to initial chemotherapy. This response to initial chemotherapy (or induction therapy) is measured by the absence of leukemia cells in the bone marrow.

28 Oct 2014

Influential colleagues convince doctors to try new therapies

Doctors are more likely to try a new therapy when they are persuaded to do so by an influential colleague, reports a new Northwestern University study whose findings on adopting innovations also have relevance for business, education and research.

28 Oct 2014

Lowering 'bad' cholesterol may help prevent aortic valve disease, study finds

An international research team led by the Research Institute of the McGill University Health Centre and Lund University has provided new evidence that aortic valve disease may be preventable.

28 Oct 2014

Patients who receive chest radiation for Wilms tumor face breast cancer risk later in life

A new study has found that patients who received chest radiation for Wilms tumor, a rare childhood cancer, face an increased risk of developing breast cancer later in life due to their radiation exposure.

28 Oct 2014

New research suggests that TEM5 protein may be a good target for cancer therapy

Do blood vessels that feed tumors differ from other blood vessels? Fourteen years ago, experiments designed to answer that question led to the discovery of several genes that are more active in tumor-associated blood vessels than in normal blood vessels. New research now reveals the normal function of one of those genes and suggests it could be a good target for anticancer drug therapy.

28 Oct 2014

Myriad's Prolaris test included in NCCN Guidelines for men with localized prostate cancer

Myriad Genetics, Inc. today announced that its Prolaris test has been included in the National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology (NCCN Guidelines) for all men with localized prostate cancer, regardless of their risk category.

28 Oct 2014

EMA's CHMP adopts final opinion on ARIAD Pharmaceuticals' Iclusig (ponatinib)

ARIAD Pharmaceuticals, Inc. today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted its final opinion on Iclusig (ponatinib) following the recommendations made by the Pharmacovigilance Risk Assessment Committee earlier this month.

27 Oct 2014

Bortezomib drug effective against chronic GVHD

Researchers at UC Davis have found that the drug bortezomib effectively treats chronic graft-versus-host disease (GVHD), a common and debilitating side effect from allogeneic hematopoietic stem cell transplants.

27 Oct 2014

Salk Institute scientists identify promising target for HIV/AIDS treatment

Like a slumbering dragon, HIV can lay dormant in a person's cells for years, evading medical treatments only to wake up and strike at a later time, quickly replicating itself and destroying the immune system.

27 Oct 2014

Study shows that obese children may mistake asthma symptoms, overuse rescue medications

New research shows obese children with asthma may mistake symptoms of breathlessness for loss of asthma control leading to high and unnecessary use of rescue medications. The study was published online in the Journal of Allergy and Clinical Immunology, the official scientific journal of the American Association of Allergy, Asthma and Immunology.

27 Oct 2014

Therapy News and Research

Study: Certain prostate cancer medications linked to cardiac death risk

New standard of care for pediatric AML patients who receive umbilical cord transplants

UCSD researchers develop novel ultrasound technology to diagnose two heart conditions

Mayo Clinic orthopedic surgeon explains how scoliosis affects Baby Boomers

Rapamycin and dasatinib combination may be beneficial in treating breast cancer, say scientists

Royal Holloway-led researchers to develop novel spinal cord injury treatment

New data demonstrates improved outcomes in psoriasis patients treated with Daivobet gel

Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

Generic aromatase inhibitors increase breast cancer treatment adherence by 50%

Pre-treatment pain intensity predicts survival of patients with head and neck cancer

Study: Obese youths with ALL have worse outcomes than lean counterparts

Influential colleagues convince doctors to try new therapies

Lowering 'bad' cholesterol may help prevent aortic valve disease, study finds

Patients who receive chest radiation for Wilms tumor face breast cancer risk later in life

New research suggests that TEM5 protein may be a good target for cancer therapy

Myriad's Prolaris test included in NCCN Guidelines for men with localized prostate cancer

EMA's CHMP adopts final opinion on ARIAD Pharmaceuticals' Iclusig (ponatinib)

Bortezomib drug effective against chronic GVHD

Salk Institute scientists identify promising target for HIV/AIDS treatment

Study shows that obese children may mistake asthma symptoms, overuse rescue medications

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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