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Researchers develop first animal model simulating eye complications linked with Graves' disease

Researchers have developed the first animal model simulating the eye complications associated with the thyroid condition Graves' disease, a breakthrough that could pave the way for better treatments, according to a recent study accepted for publication in The Endocrine Society's journal Endocrinology.

3 Sep 2013

Omecamtiv mecarbil fails to achieve primary endpoint in phase II ATOMIC-AHF study

Omecamtiv mecarbil, a cardiac myosin-activator, did not achieve its primary efficacy endpoint in reducing dyspnoea (shortness of breath) in patients with acute heart failure, according to the results of the phase II ATOMIC-AHF (Acute Treatment with Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure) study.

3 Sep 2013

Study assesses relationship between BMI and CV events in hypertensive patients with diabetes

Low BMI is a risk factor for CVD in hypertensive patients with diabetes, according to research presented at the ESC Congress today by Dr Takanori Nagahiro from Japan. The findings provide evidence for an obesity paradox in hypertensive patients with glucose intolerance.

3 Sep 2013

Research: Male sexual development less stable than other genetic programs

The idea that men and women are fundamentally different from each other is widely accepted. And throughout the world, this has created distinct ideas about which social and physical characteristics are necessary in each gender to maintain healthy human development.

3 Sep 2013

Women are 25% less likely to die post TAVI than men, says doctor

Dr Sherif said: "Earlier studies on the impact of gender on outcome after transcatheter aortic valve implantation (TAVI) have had conflicting results. A Canadian study reported in 641 consecutive patients that female sex is associated with a better long-term and short-term survival after TAVI.1 An Italian study of 305 high risk patients found no gender differences in composite safety and efficacy endpoints at 30 days and one year after TAVI."2

2 Sep 2013

TAVI is safe therapeutic option than redo cardiac surgery

Use of bioprosthetic heart valves has dramatically increased (from 18% in 1991 to 59% in 2003), mainly in older patients with comorbidities. This is due to the increased risk of bleeding complications associated with lifelong use of anticoagulation for mechanical prostheses.

2 Sep 2013

2013 Multicultural Health Week: Working together for safe, quality care

Enhancing communication about medication safety in languages other than English is at the very heart of Multicultural Health Week, Minister for Health Jillian Skinner and Minister for Citizenship and Communities Victor Dominello said today.

2 Sep 2013

DE-MRI before ablation can stage atrial fibrosis and help predict success treatment

In patients with atrial fibrillation, delayed enhancement magnetic resonance imaging (DE-MRI) performed before ablative treatment can stage the degree of damaged heart tissue (atrial fibrosis) and help predict whether treatment will be successful or not, according to results of Delayed Enhancement - MRI determinant of successful Catheter Ablation of Atrial Fibrillation (DECAAF) trial.

2 Sep 2013

Each daily minute of higher-intensity activity lowers odds of obesity

To win the war against weight gain, it turns out that every skirmish matters - as long as the physical activity puts your heart and lungs to work.

2 Sep 2013

Leisure-time physical activity might reduce risk of SCD among men with low CRF

Dr Laukkanen said: "Sudden cardiac death (SCD) accounts for approximately 50% of deaths from coronary heart disease. SCD typically occurs shortly after the onset of symptoms, leaving little time for effective medical interventions, and most cases occur outside hospital with few or no early warning signs. Finding ways to identify individuals at elevated risk of SCD would allow early interventions on risk factors to be implemented."

2 Sep 2013

Pacemakers implanted for slow heart rhythm restore life expectancy to normal levels

Pacemakers implanted for slow heart rhythm restore life expectancy to normal levels, reveals research presented at ESC Congress 2013 today by Dr Erik O. Udo from the Netherlands. The findings provide a new reference point for the prognosis of modern pacemaker patients.

2 Sep 2013

Being overweight but metabolically healthy is not linked with increased risk of heart attack

Metabolically healthy women have the same cardiovascular disease risk regardless of their BMI, according to research presented at the ESC Congress today by Dr S-ren Sk-tt Andersen and Dr Michelle Schmiegelow from Denmark.

2 Sep 2013

Mass screening programme of 75-76 year olds to identify undiagnosed AF

Stroke is the second cause of death worldwide. Atrial fibrillation is the most common clinically relevant cardiac arrhythmia in Europe, affecting approximately 1.5-2% of the general population.1 Prevalence is estimated to double in the next 50 years as the population ages.

2 Sep 2013

Anti-diabetic drug alogliptin meets primary endpoint in EXAMINE trial

Patients with type 2 diabetes and high cardiovascular risk due to recent acute coronary syndromes had similar rates of cardiovascular events when treated with the anti-diabetic agent alogliptin compared to placebo according to results of the Examination of Cardiovascular Outcomes with Alogliptin versus Standard of Care trial presented at the European Society of Cardiology Congress.

2 Sep 2013

Use of anticoagulant does not reduce ischemic events among patients undergoing PCI

Use of the novel anticoagulant otamixaban did not reduce ischemic events compared with unfractionated heparin plus eptifibatide but increased bleeding among patients with non-ST-segment elevation acute coronary syndromes undergoing a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), according to a study published by JAMA.

2 Sep 2013

Effectiveness of community-based rehabilitation programme for cardiovascular prevention

With a growing incidence of cardiovascular disease in Asia, lifestyle modification such as weight loss and routine exercise plays an important role in early primary cardiovascular disease prevention.

2 Sep 2013

Despite living with highest risk factors for heart disease, people in high income countries suffer less

Despite living with the highest risk factors for heart disease, people in high income countries suffer less from serious cardiovascular disease, says an international study by the global PURE (Prospective Urban Rural Epidemiology ) collaboration and led by McMaster University researchers.

2 Sep 2013

Research: General practitioners undertreat women with atrial fibrillation

General practitioners (GPs) undertreat women with atrial fibrillation (AF), according to research presented at ESC Congress 2013 today by Dr Pierre Sabouret from France. The analysis of more than 15,000 patients showed that women were undertreated with antithrombotic medications compared to men regardless of their stroke risk and comorbidities.

2 Sep 2013

Aortic stenosis doubles in patients with family history of the condition

Aortic stenosis is the most common heart valve disease in the elderly. It is associated with congenital bicuspid aortic valve and previous rheumatic heart disease, but is also often caused by calcification of a normal valve. Calcification of a normal valve may be associated with atherosclerotic changes in the portion of the aorta closest to the valve.

2 Sep 2013

Study examines impact of stopping smoking on risk of cardiovascular events

Dr Min said: "Smoking is an established risk factor for cardiovascular disease. Studies have identified that quitting smoking can reduce heart attacks and death but have not examined the relationship of this salutary effect on the presence and severity of coronary artery disease. Our study aimed to find out what impact stopping smoking had on the risk of cardiovascular events, death and the severity of CAD."

2 Sep 2013

Heart News and Research

Researchers develop first animal model simulating eye complications linked with Graves' disease

Omecamtiv mecarbil fails to achieve primary endpoint in phase II ATOMIC-AHF study

Study assesses relationship between BMI and CV events in hypertensive patients with diabetes

Research: Male sexual development less stable than other genetic programs

Women are 25% less likely to die post TAVI than men, says doctor

TAVI is safe therapeutic option than redo cardiac surgery

2013 Multicultural Health Week: Working together for safe, quality care

DE-MRI before ablation can stage atrial fibrosis and help predict success treatment

Each daily minute of higher-intensity activity lowers odds of obesity

Leisure-time physical activity might reduce risk of SCD among men with low CRF

Pacemakers implanted for slow heart rhythm restore life expectancy to normal levels

Being overweight but metabolically healthy is not linked with increased risk of heart attack

Mass screening programme of 75-76 year olds to identify undiagnosed AF

Anti-diabetic drug alogliptin meets primary endpoint in EXAMINE trial

Use of anticoagulant does not reduce ischemic events among patients undergoing PCI

Effectiveness of community-based rehabilitation programme for cardiovascular prevention

Despite living with highest risk factors for heart disease, people in high income countries suffer less

Research: General practitioners undertreat women with atrial fibrillation

Aortic stenosis doubles in patients with family history of the condition

Study examines impact of stopping smoking on risk of cardiovascular events

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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