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Minigenes produced by CRISPR combat liver disease in mice

A new gene-editing technique based on CRISPR was used to successfully avoid the development of a liver disease that can be caused by hundreds of mutations, as well as to ease the symptoms in mice. This proof-of-concept study was published online in the journal Science Advances in February 2020.

12 Feb 2020

Exploring common tech-related injuries

Nearly half of all U.S. adults say they can't live without their smartphones, according to the Pew Research Center. But what happens when our fondness for the latest electronic gadgets creates more pain than gain?

12 Feb 2020

Vitamin D deficiency in postmenopausal women linked to disc degeneration and lower back pain

Lumbar disc degeneration and resulting lower back pain become greater concerns with age and disproportionately affect women more than men, likely as a result of decreasing estrogen levels during menopause.

12 Feb 2020

Accumulated brain protein affects genes in Alzheimer's disease

A new study published in February 2020 in the journal Cell Reports shows how the build-up of specific brain cell proteins are linked to altered gene expression that causes the symptoms of Alzheimer's disease (AD).

11 Feb 2020

Heroin use increasing among American adults

Earlier studies have shown a startling sevenfold increase in illnesses and deaths directly traceable to heroin use in the USA over less than 20 years. Along with this epidemic, HIV and hepatitis infections acquired by injections of drugs have also broken out in large clusters in many places. Yet, the extent of heroin use itself has been neglected. The current study looked at this overlooked area of research.

11 Feb 2020

Nerve insulation renewed to create long-term learning

A new study published in February 2020, in the journal Nature Neuroscience, shows that short-term learning occurs rapidly, but for it to become a long-term memory, brain cells must form more myelin, an insulating fatty material.

10 Feb 2020

Research uncovers protective role of astrocytes in sporadic motor neuron disease

Support cells in the nervous system help protect motor neurons in the early-stages of sporadic motor neuron disease, according to new research from the Crick and UCL.

10 Feb 2020

Novel method to monitor residual disease after treatment in high-risk neuroblastoma patients

A research group led by Professor NISHIMURA Noriyuki (Graduate School of Health Sciences, Kobe University) has developed a new method to monitor the residual disease after treatment in high-risk neuroblastoma patients.

9 Feb 2020

Researchers examine the effects of yoga, tai chi, and qigong on chronic low back pain

It's a pain. About 80 percent of adults in the United States will experience lower back pain at some point. Treating back pain typically involves medication, including opioids, surgery, therapy and self-care options.

6 Feb 2020

New technology distinguishes between two progressive neurodegenerative diseases

Scientists have found a way to distinguish between two progressive neurodegenerative diseases, Parkinson's disease and multiple system atrophy, using a technology developed by a researcher at The University of Texas Health Science Center at Houston.

6 Feb 2020

Gut bacteria help regulate contraction and relaxation of colon muscles

Micro-organisms in the gut support healthy digestion by helping nerve cells within the intestine to regulate the contraction and relaxation of the muscle wall of the colon, according to new research from the Crick and Bern University.

5 Feb 2020

Age-linked cognitive decline could be slowed by immune activation

A new study published in February 2020 in the Journal of Experimental Medicine (JEM), reports that activating a specific type of immune cell found in the brain could delay reduced cognition often found in older people, and even prevent neurologic degeneration of age.

5 Feb 2020

Study sheds new light on genetic relationship between three mood disorders

Researchers shed new light on the genetic relationship between three mood disorders associated with depression--major depression and bipolar disorder types 1 and 2, in a new study in the journal Biological Psychiatry, published by Elsevier.

5 Feb 2020

Advanced X-ray combination technique aids tuberculosis and osteoporosis research

With an advanced X-ray combination technique, scientists have traced nanocarriers for tuberculosis drugs within cells with very high precision.

4 Feb 2020

Making it all work: brain-dependent immune activation in embryos

How does the immune system develop its functionality? This has been an ongoing area of research for biologists. Now, a new study published in the journal NPJ Regenerative Medicine in February 2020 shows that in very early fetal life the brain must signal directions to the developing immune system to help it defend the body from infectious agents. This signaling markedly improves the capability of the embryo to survive when faced with bacterial infection.

4 Feb 2020

People with ASD have cellular abnormality that impairs myelin production, study reveals

People with autism spectrum disorder appear to suffer malfunctions in a cell that produces a special coating around nerve fibers that facilitates efficient electrical communication across the brain.

4 Feb 2020

Many older people in Australia are missing out on shingles vaccination

Many older Australians are missing out on the chance to get vaccinated against shingles, according to the latest edition of Australian Prescriber.

3 Feb 2020

Reduced scar formation in the central nervous system

Neural stem and progenitor cells, from the so-called subventricular zone, can help to repair a brain damaged by central nervous system disorders.

3 Feb 2020

Increased brain growth, mutations and autism linked in new study

Salk Institute researchers have now found a pattern of DNA damage that is unique to brain cells derived from individuals with a single form of autism spectrum disorder (ASD) called macrocephalic ASD. The study, published in the journal Cell Stem Cell in January 2020, may offer an explanation about the developmental misstep that caused this disease.

30 Jan 2020

Gene-editing taken to advanced levels in human stem cells

A new study published in the journal Stem Cell Reports in January 2020 reports the use of an adaptation to a commonly used gene editing technology to achieve a more than 900% increase in efficiency.

30 Jan 2020